PMID- 33348075
OWN - NLM
STAT- MEDLINE
DCOM- 20210514
LR  - 20210514
IS  - 1873-1597 (Electronic)
IS  - 1572-1000 (Linking)
VI  - 33
DP  - 2021 Mar
TI  - Biosynthesis of silver capped magnesium oxide nanocomposite using Olea cuspidata 
      leaf extract and their photocatalytic, antioxidant and antibacterial activity.
PG  - 102153
LID - S1572-1000(20)30507-X [pii]
LID - 10.1016/j.pdpdt.2020.102153 [doi]
AB  - Green chemistry is a modern area of research which covers synthesis of 
      nanomaterials through useful, environmentally, economically friendly techniques 
      and their use in different fields. The synthesis involves the formation of 
      bimetallic nanomaterials to enhance their synergistic relationship and achieve 
      special modulated properties. That's why bimetallic nanomaterials are extremely 
      important and gaining interest among researchers in the field of medicinal 
      chemistry for the treatment of various diseases. In this particular study, 
      bimetallic nanoparticles synthesis was done by reduction procedure using leaf 
      extract of Olea cuspidata. The phytochemicals in leaf extract act as stabilizing 
      and capping agent in reduction of precursor's salts. The characterization of 
      green synthesized Ag@MgO nanocomposite was done through several analytical 
      techniques such as ultraviolet-visible (UV-vis) spectroscopy, X-ray diffraction 
      (XRD), Fourier-transform infrared spectroscopy (FTIR), Scanning electron 
      microscope (SEM), High resolution transmission electron microscope (HRTEM) and 
      Zeta potential. To explore the biological potential of synthesized nanocomposite, 
      antibacterial activities against gram negative (Escherichia coli) bacteria and 
      gram positive (Staphylococcus aureus) has been evaluated. The photocatalytic 
      activity in contrary to methylene blue (MB) decomposition was seen efficiently. 
      Moreover, the antioxidant nature of green synthesized Ag@MgO nanocomposite was 
      analyzed by destabilizing and scavenging maximum percentage (93 %) of dangerous 
      and harmful 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical. The best and 
      surprising results provided the information for the presence of essential and 
      vital components in Olea Cuspidata in the form of organic acids (Citrus Acid) 
      aids in stabilizing the entire structure with enhanced properties. Up to the best 
      of our knowledge, the facts and results obtained regarding the structure of 
      Ag@MgO nanocomposite clearly illustrates the uniqueness of green chemistry and 
      also its role in future developing multifunctional nanoparticles in the field of 
      nanobiotechnology.
CI  - Copyright (c) 2020 Elsevier B.V. All rights reserved.
FAU - Khan, Afaq Ullah
AU  - Khan AU
AD  - State Key Laboratory of Chemical Resource Engineering, Beijing University of 
      Chemical Technology, Beijing, 100029, PR China.
FAU - Khan, Arif Ullah
AU  - Khan AU
AD  - State Key Laboratory of Chemical Resource Engineering, Beijing University of 
      Chemical Technology, Beijing, 100029, PR China; Beijing Advaced Innovation Centre 
      for Soft Matter Science and Engineering, Beijing University of Chemical 
      Technology, Beijing, 100029, PR China. Electronic address: khanbuct@gmail.com.
FAU - Li, Baoshan
AU  - Li B
AD  - State Key Laboratory of Chemical Resource Engineering, Beijing University of 
      Chemical Technology, Beijing, 100029, PR China. Electronic address: 
      bsli@mail.buct.edu.cn.
FAU - Mahnashi, Mater H
AU  - Mahnashi MH
AD  - Department of Pharmaceutical Chemistry, College of Pharmacy, Najran University, 
      Najran, Saudi Arabia.
FAU - Alyami, Bandar A
AU  - Alyami BA
AD  - Department of Pharmaceutical Chemistry, College of Pharmacy, Najran University, 
      Najran, Saudi Arabia.
FAU - Alqahtani, Yahya S
AU  - Alqahtani YS
AD  - Department of Pharmaceutical Chemistry, College of Pharmacy, Najran University, 
      Najran, Saudi Arabia.
FAU - Alqarni, Ali O
AU  - Alqarni AO
AD  - Department of Pharmaceutical Chemistry, College of Pharmacy, Najran University, 
      Najran, Saudi Arabia.
FAU - Khan, Zia Ul Haq
AU  - Khan ZUH
AD  - Department of Environmental Sciences, COMSATS University, Vehari, 61100 Pakistan.
FAU - Ullah, Sami
AU  - Ullah S
AD  - COMSATS University Islamabad, Abbottabad Campus, Pakistan.
FAU - Wasim, Muhammad
AU  - Wasim M
AD  - PGR Medicine Group b Dermatology Saidu Group of Teaching Hospital Swat, KPK, 
      Pakistan.
FAU - Khan, Qudrat Ullah
AU  - Khan QU
AD  - College of Physics and Optoelectronics, Shenzhen University, Nanhai Ave, 3688, 
      Shenzhen, Guangdong, 518060, PR China.
FAU - Ahmad, Waqas
AU  - Ahmad W
AD  - State Key Laboratory of Chemical Resource Engineering, Beijing University of 
      Chemical Technology, Beijing, 100029, PR China.
LA  - eng
PT  - Journal Article
DEP - 20201225
PL  - Netherlands
TA  - Photodiagnosis Photodyn Ther
JT  - Photodiagnosis and photodynamic therapy
JID - 101226123
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Antioxidants)
RN  - 0 (Photosensitizing Agents)
RN  - 0 (Plant Extracts)
RN  - 3A3U0GI71G (Magnesium Oxide)
RN  - 3M4G523W1G (Silver)
SB  - IM
MH  - Anti-Bacterial Agents/pharmacology
MH  - Antioxidants/pharmacology
MH  - Magnesium Oxide
MH  - *Metal Nanoparticles
MH  - *Nanocomposites
MH  - *Olea
MH  - *Photochemotherapy/methods
MH  - Photosensitizing Agents
MH  - Plant Extracts/pharmacology
MH  - Silver
OTO - NOTNLM
OT  - Ag@MgO nanocomposites
OT  - Cytotoxicity
OT  - Olea cuspidata
OT  - Photodegradation of methylene blue
EDAT- 2020/12/22 06:00
MHDA- 2021/05/15 06:00
CRDT- 2020/12/21 20:11
PHST- 2020/09/13 00:00 [received]
PHST- 2020/12/04 00:00 [revised]
PHST- 2020/12/07 00:00 [accepted]
PHST- 2020/12/22 06:00 [pubmed]
PHST- 2021/05/15 06:00 [medline]
PHST- 2020/12/21 20:11 [entrez]
AID - S1572-1000(20)30507-X [pii]
AID - 10.1016/j.pdpdt.2020.102153 [doi]
PST - ppublish
SO  - Photodiagnosis Photodyn Ther. 2021 Mar;33:102153. doi: 
      10.1016/j.pdpdt.2020.102153. Epub 2020 Dec 25.