PMID- 33350296
OWN - NLM
STAT- MEDLINE
DCOM- 20211231
LR  - 20211231
IS  - 1303-6165 (Electronic)
IS  - 1300-0144 (Print)
IS  - 1300-0144 (Linking)
VI  - 51
IP  - 4
DP  - 2021 Aug 30
TI  - Pediatric extracorporeal cardiopulmonary resuscitation: single-center study.
PG  - 1733-1737
LID - 10.3906/sag-2002-10 [doi]
AB  - BACKGROUND/AIM: Extracorporeal cardiopulmonary resuscitation (ECPR) is defined as 
      the venoarterial extracorporeal membrane oxygenation (VA-ECMO) support in a 
      patient who experienced a sudden pulseless condition attributable to cessation of 
      cardiac mechanical activity and circulation. We aimed to evaluate the clinical 
      outcomes of our ECPR experience in a pediatric patient population. MATERIALS AND 
      METHODS: Between September 2014 and November 2017, 15 children were supported 
      with ECPR following in-hospital cardiac arrest (IHCA) in our hospitals. VA-ECMO 
      setting was established for all patients. Pediatric cerebral performance category 
      (PCPC) scales and long-term neurological prognosis of the survivors were 
      assessed. RESULTS: The median age of the study population was 60 (4-156) months. 
      The median weight was 18 (4.8-145) kg, height was 115 (63-172) cm, and body 
      surface area was 0.73 (0.27-2.49) m2. The cause of cardiac arrest was a cardiac 
      and circulatory failure in 12 patients (80%) and noncardiac causes in 20%. 
      Dysrhythmia was present in 46%, septic shock in 13%, bleeding in 6%, low cardiac 
      output syndrome in 13%, and airway disease in 6% of the study population. Median 
      low-flow time was 95 (range 20-320) min. Central VA- ECMO cannulation was placed 
      in only 2 (13.3%) cases. However, the return of spontaneous circulation (ROSC) 
      was obtained in 10 (66.6%) patients, and 5 (50%) of them survived. Overall, 5 
      patients were discharged from the hospital. Finally, survival following ECPR was 
      33.3%, and all survivors were neurologically intact at hospital-discharge. 
      CONCLUSION: ECPR can be a life-saving therapeutic strategy using a promising 
      technology in the pediatric IHCA population. Early initiation and a 
      well-coordinated, skilled, and dedicated ECMO team are the mainstay for better 
      survival rates.
CI  - This work is licensed under a Creative Commons Attribution 4.0 International 
      License.
FAU - Kendirli, Tanil
AU  - Kendirli T
AUID- ORCID: 0000-0001-9458-2803
AD  - Department of Pediatric Critical care Medicine, Faculty of Medicine, Ankara 
      University, Ankara, Turkey
FAU - Ozcan, Serhan
AU  - Ozcan S
AUID- ORCID: 0000-0003-4465-6063
AD  - Department of Pediatric Critical care Medicine, Faculty of Medicine, Ankara 
      University, Ankara, Turkey
FAU - Havan, Merve
AU  - Havan M
AUID- ORCID: 0000-0002-8199-0530
AD  - Department of Pediatric Critical care Medicine, Faculty of Medicine, Ankara 
      University, Ankara, Turkey
FAU - Baran, Cagdas
AU  - Baran C
AUID- ORCID: 0000-0003-3431-7906
AD  - Department of Cardiovascular Surgery, Faculty of Medicine, Ankara University, 
      Ankara, Turkey
FAU - Cakici, Mehmet
AU  - Cakici M
AUID- ORCID: 0000-0002-9687-1147
AD  - Department of Cardiovascular Surgery, Faculty of Medicine, Ankara University, 
      Ankara, Turkey
FAU - Arici, Burcu
AU  - Arici B
AUID- ORCID: 0000-0002-9824-9220
AD  - Department of Cardiovascular Surgery, Faculty of Medicine, Ankara University, 
      Ankara, Turkey
FAU - Selvi Can, Ozlem
AU  - Selvi Can O
AUID- ORCID: 0000-0002-1927-9238
AD  - Department of Anesthesiology and Reanimation, Faculty of Medicine, Ankara 
      University, Ankara, Turkey
FAU - Eyileten, Zeynep
AU  - Eyileten Z
AUID- ORCID: 0000-0003-3405-7139
AD  - Department of Cardiovascular Surgery, Faculty of Medicine, Ankara University, 
      Ankara, Turkey
FAU - Ucar, Tayfun
AU  - Ucar T
AUID- ORCID: 0000-0003-3386-0691
AD  - Department of Pediatric Cardiology, Faculty of Medicine, Ankara University, 
      Ankara, Turkey
FAU - Tutar, Ercan
AU  - Tutar E
AUID- ORCID: 0000-0003-0795-0810
AD  - Department of Pediatric Cardiology, Faculty of Medicine, Ankara University, 
      Ankara, Turkey
FAU - Akar, Ahmet Ruchan
AU  - Akar AR
AUID- ORCID: 0000-0002-5191-5505
AD  - Department of Cardiovascular Surgery, Faculty of Medicine, Ankara University, 
      Ankara, Turkey
LA  - eng
PT  - Journal Article
DEP - 20210830
PL  - Turkey
TA  - Turk J Med Sci
JT  - Turkish journal of medical sciences
JID - 9441758
SB  - IM
MH  - *Cardiopulmonary Resuscitation
MH  - Child, Preschool
MH  - *Extracorporeal Membrane Oxygenation
MH  - Female
MH  - Heart Arrest/mortality/*therapy
MH  - Humans
MH  - Infant
MH  - Male
MH  - Retrospective Studies
MH  - Survival Rate
MH  - Treatment Outcome
PMC - PMC8569742
OTO - NOTNLM
OT  - Extracorporeal cardiopulmonary resuscitation
OT  - extracorporeal membrane oxygenation
OT  - children
COIS- CONFLICT OF INTEREST: The authors of this manuscript have no conflicts of 
      interest to disclose, as described by the Turkish Journal of Medical Sciences.
EDAT- 2020/12/23 06:00
MHDA- 2022/01/01 06:00
PMCR- 2021/08/30
CRDT- 2020/12/22 07:31
PHST- 2020/02/02 00:00 [received]
PHST- 2020/12/21 00:00 [accepted]
PHST- 2020/12/22 07:31 [entrez]
PHST- 2020/12/23 06:00 [pubmed]
PHST- 2022/01/01 06:00 [medline]
PHST- 2021/08/30 00:00 [pmc-release]
AID - 10.3906/sag-2002-10 [doi]
PST - epublish
SO  - Turk J Med Sci. 2021 Aug 30;51(4):1733-1737. doi: 10.3906/sag-2002-10.