PMID- 33369670
OWN - NLM
STAT- MEDLINE
DCOM- 20210518
LR  - 20211014
IS  - 1524-4040 (Electronic)
IS  - 0148-396X (Linking)
VI  - 88
IP  - 4
DP  - 2021 Mar 15
TI  - Contemporary Analysis of Minimal Clinically Important Difference in the 
      Neurosurgical Literature.
PG  - 713-719
LID - 10.1093/neuros/nyaa490 [doi]
AB  - BACKGROUND: Minimal clinically important difference (MCID) is determined when a 
      patient or physician defines the minimal change that outweighs the costs and 
      untoward effects of a treatment. These measurements are "anchored" to validated 
      quality-of-life instruments or physician-rated, disease-activity indices. To 
      capture the subjective clinical experience in a measurable way, there is an 
      increasing use of MCID. OBJECTIVE: To review the overall concept, method of 
      calculation, strengths, and weaknesses of MCID and its application in the 
      neurosurgical literature. METHODS: Recent articles were reviewed based on PubMed 
      query. To illustrate the strengths and limitations of MCID, studies regarding the 
      measurement of pain are emphasized and their impact on subsequent publications 
      queried. RESULTS: MCID varies by population baseline characteristics and 
      calculation method. In the context of pain, MCID varied based on the quality of 
      pain, chronicity, and treatment options. CONCLUSION: MCID evaluates outcomes 
      relative to whether they provide a meaningful change to patients, incorporating 
      the risks and benefits of a treatment. Using MCID in the process of evaluating 
      outcomes helps to avoid the error of interpreting a small but statistically 
      significant outcome difference as being clinically important.
CI  - (c) Congress of Neurological Surgeons 2020.
FAU - Zervos, Thomas M
AU  - Zervos TM
FAU - Asmaro, Karam
AU  - Asmaro K
FAU - Air, Ellen L
AU  - Air EL
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Systematic Review
PL  - United States
TA  - Neurosurgery
JT  - Neurosurgery
JID - 7802914
SB  - IM
CIN - Neurosurgery. 2021 Jun 15;89(1):E84. PMID: 33825876
CIN - Neurosurgery. 2021 Jun 15;89(1):E82-E83. PMID: 33826735
CIN - Neurosurgery. 2021 Sep 15;89(4):E242-E243. PMID: 34293153
CIN - Neurosurgery. 2021 Sep 15;89(4):E244. PMID: 34293157
MH  - Adult
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Minimal Clinically Important Difference
MH  - Neurosurgical Procedures/*standards/trends
MH  - Outcome Assessment, Health Care/*standards/trends
MH  - Pain Measurement/*standards/trends
MH  - Quality of Life/psychology
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Clinimetrics
OT  - Health-related quality of life
OT  - Minimal clinically important difference
OT  - Outcome measures
OT  - Patient-reported outcomes
OT  - Quality of life
OT  - Statistical significance
EDAT- 2020/12/29 06:00
MHDA- 2021/05/19 06:00
CRDT- 2020/12/28 13:16
PHST- 2020/01/31 00:00 [received]
PHST- 2020/09/09 00:00 [accepted]
PHST- 2020/12/29 06:00 [pubmed]
PHST- 2021/05/19 06:00 [medline]
PHST- 2020/12/28 13:16 [entrez]
AID - 6053822 [pii]
AID - 10.1093/neuros/nyaa490 [doi]
PST - ppublish
SO  - Neurosurgery. 2021 Mar 15;88(4):713-719. doi: 10.1093/neuros/nyaa490.