PMID- 33376314
OWN - NLM
STAT- MEDLINE
DCOM- 20210421
LR  - 20220419
IS  - 1178-1998 (Electronic)
IS  - 1176-9092 (Print)
IS  - 1176-9092 (Linking)
VI  - 15
DP  - 2020
TI  - Two-year Outcome of Quality of Life and Health Status for the Elderly with 
      Chronic Limb-threatening Ischemia.
PG  - 2383-2395
LID - 10.2147/CIA.S272078 [doi]
AB  - PURPOSE: In elderly patients with chronic limb-threatening ischemia (CLTI), there 
      is little scientific understanding of the long-term changes of quality of life 
      (QoL) and health status (HS) after treatment. The primary goal of this study was 
      to provide long-term QoL and HS results for elderly CLTI patients after therapy. 
      Treatments consisted of endovascular revascularization, surgical 
      revascularization, or conservative treatment. Furthermore, the aim of this study 
      was to identify the distinctive trajectories of QoL and HS. PATIENTS AND METHODS: 
      CLTI patients aged >/=70 years were included in a prospective observational cohort 
      study with a two-year follow-up. The WHOQOL-BREF was used to asses QoL. The 
      12-Item Short Form Health Survey was used to measure HS. The QoL and HS scores 
      were compared to the scores in the general elderly Dutch population. Latent class 
      trajectory analysis was used. RESULTS: A total of 195 patients were included in 
      this study. After two years, in all treatment groups patients showed 
      significantly higher physical QoL score compared to baseline and there was no 
      significant difference with the corresponding values in the elderly Dutch 
      population. In the latent class trajectory analysis, there were no overlapping 
      risk factors for poorer QoL or HS. CONCLUSION: This study shows that QoL levels 
      in surviving elderly CLTI patients in the long-term do not differ from the 
      corresponding values for elderly in the general population. There were no 
      disparities in sociodemographic, clinical and treatment characteristics 
      associated with poorer QoL and HS. This study was carried out to encourage 
      further analysis of the influence of biopsychosocial characteristics on QoL and 
      HS in elderly CLTI patients.
CI  - (c) 2020 Peters et al.
FAU - Peters, Chloe M L
AU  - Peters CML
AD  - Department of Surgery, Amphia Hospital, Breda, The Netherlands.
FAU - Lodder, Paul
AU  - Lodder P
AD  - Department of Medical and Clinical Psychology, Tilburg University, Tilburg, The 
      Netherlands.
AD  - Department of Methodology and Statistics, Tilburg University, Tilburg, The 
      Netherlands.
FAU - de Vries, Jolanda
AU  - de Vries J
AUID- ORCID: 0000-0003-3002-1323
AD  - Department of Medical and Clinical Psychology, Tilburg University, Tilburg, The 
      Netherlands.
AD  - Department of Medical Psychology, Elisabeth-TweeSteden Hospital Tilburg 
      University, Tilburg, The Netherlands.
FAU - Steunenberg, Stijn L
AU  - Steunenberg SL
AUID- ORCID: 0000-0003-3539-0582
AD  - Department of Surgery, Amphia Hospital, Breda, The Netherlands.
FAU - Veen, Eelco J
AU  - Veen EJ
AD  - Department of Surgery, Amphia Hospital, Breda, The Netherlands.
FAU - de Groot, Hans G W
AU  - de Groot HGW
AUID- ORCID: 0000-0002-1610-7449
AD  - Department of Surgery, Amphia Hospital, Breda, The Netherlands.
FAU - Ho, Gwan H
AU  - Ho GH
AD  - Department of Surgery, Amphia Hospital, Breda, The Netherlands.
FAU - van der Laan, Lijckle
AU  - van der Laan L
AD  - Department of Surgery, Amphia Hospital, Breda, The Netherlands.
AD  - Department of Cardiovascular Science, UZ Leuven - University Hospitals, Leuven, 
      Belgium.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20201222
PL  - New Zealand
TA  - Clin Interv Aging
JT  - Clinical interventions in aging
JID - 101273480
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Chronic Disease
MH  - Female
MH  - *Health Status
MH  - Humans
MH  - Male
MH  - Netherlands
MH  - Peripheral Arterial Disease/psychology/*surgery
MH  - Prospective Studies
MH  - *Quality of Life
MH  - Risk Factors
MH  - Severity of Illness Index
MH  - Socioeconomic Factors
MH  - Treatment Outcome
MH  - Vascular Surgical Procedures/psychology/*statistics & numerical data
PMC - PMC7765754
OTO - NOTNLM
OT  - chronic limb-threatening ischemia
OT  - frail elderly
OT  - health status
OT  - peripheral arterial disease
OT  - quality of life
COIS- The authors report no conflicts of interest in this work.
EDAT- 2020/12/31 06:00
MHDA- 2021/04/22 06:00
PMCR- 2020/12/22
CRDT- 2020/12/30 05:20
PHST- 2020/07/14 00:00 [received]
PHST- 2020/10/28 00:00 [accepted]
PHST- 2020/12/30 05:20 [entrez]
PHST- 2020/12/31 06:00 [pubmed]
PHST- 2021/04/22 06:00 [medline]
PHST- 2020/12/22 00:00 [pmc-release]
AID - 272078 [pii]
AID - 10.2147/CIA.S272078 [doi]
PST - epublish
SO  - Clin Interv Aging. 2020 Dec 22;15:2383-2395. doi: 10.2147/CIA.S272078. 
      eCollection 2020.