PMID- 33376375 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220419 IS - 1178-7007 (Print) IS - 1178-7007 (Electronic) IS - 1178-7007 (Linking) VI - 13 DP - 2020 TI - Association of Daily Home-Based Hot Water Bathing and Glycemic Control in Ambulatory Japanese Patients with Type 2 Diabetes Mellitus During the COVID-19 Pandemic: A Multicenter Cross-Sectional Study. PG - 5059-5069 LID - 10.2147/DMSO.S279270 [doi] AB - PURPOSE: To clarify the relationship between daily hot water bathing (HWB) at home and glycemic control in middle-aged and elderly ambulatory patients with type 2 diabetes mellitus (T2DM). METHODS: We defined hemoglobin A1c (HbA1c) as the main outcome. We set 7.0% based on the mean value of the dependent variable as the cut-off point for analysis. Frequency of HWB was an explanatory variable. A two-sample t-test was used to compare between groups with continuous variables. Multiple logistic regression analysis was performed for frequency, adjusted age, sex, BMI, T2DM duration (Model 1), and other confounding factors (Model 2). Odds ratio (OR) and 95% confidence interval (95% CI) were calculated. RESULTS: Among 838 patients, there was a significant difference (p<0.001) in age between males (n=528, 62.8+/-8.7 years) and females (n=310, 65.0+/-8.1 years). In Model 1, compared with participants who used HWB more than seven times a week, those with poorly controlled HbA1c were significantly associated with low frequency of HWB: four to six times a week (OR 1.32, 95% CI 0.87-1.99) and less than three times a week (OR 1.43, 95% CI 0.98-2.10); p-value for overall trend was 0.041. In Model 2, p-value for overall trend was 0.138. CONCLUSION: A higher frequency of HWB was moderately associated with a decreased risk of poor glycemic control in middle-aged and elderly ambulatory patients with T2DM. CI - (c) 2020 Kamioka et al. FAU - Kamioka, Hiroharu AU - Kamioka H AD - Faculty of Regional Environment Science, Tokyo University of Agriculture, Tokyo, Japan. FAU - Mori, Yasunori AU - Mori Y AD - Mie Prefecture Health and Environment Research Institute, Yokkaichi, Mie, Japan. FAU - Horiuchi, Takahiko AU - Horiuchi T AUID- ORCID: 0000-0002-1770-1087 AD - Department of Internal Medicine, Kyushu University Beppu Hospital, Beppu, Oita, Japan. FAU - Hayashi, Takahito AU - Hayashi T AD - Department of Legal Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan. FAU - Ohmura, Koichiro AU - Ohmura K AD - Department of Rheumatology and Clinical Immunology, Kyoto University Graduate School of Medicine, Kyoto, Japan. FAU - Yamaguchi, Satoru AU - Yamaguchi S AD - Department of Oriental Medicine, Saitama Medical University, Saitama, Japan. FAU - Kato, Mitsutoshi AU - Kato M AD - Kato Clinic of Internal Medicine, Tokyo, Japan. LA - eng PT - Journal Article DEP - 20201222 PL - New Zealand TA - Diabetes Metab Syndr Obes JT - Diabetes, metabolic syndrome and obesity : targets and therapy JID - 101515585 PMC - PMC7764630 OTO - NOTNLM OT - hemoglobin A1c OT - hot water bathing OT - middle-aged and elderly ambulatory patients OT - type 2 diabetes COIS- The authors have no conflicts of interest to disclose for this work. EDAT- 2020/12/31 06:00 MHDA- 2020/12/31 06:01 PMCR- 2020/12/22 CRDT- 2020/12/30 05:20 PHST- 2020/09/12 00:00 [received] PHST- 2020/12/07 00:00 [accepted] PHST- 2020/12/30 05:20 [entrez] PHST- 2020/12/31 06:00 [pubmed] PHST- 2020/12/31 06:01 [medline] PHST- 2020/12/22 00:00 [pmc-release] AID - 279270 [pii] AID - 10.2147/DMSO.S279270 [doi] PST - epublish SO - Diabetes Metab Syndr Obes. 2020 Dec 22;13:5059-5069. doi: 10.2147/DMSO.S279270. eCollection 2020.