PMID- 33379116
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20210108
LR  - 20210108
IS  - 1873-3573 (Electronic)
IS  - 0039-9140 (Linking)
VI  - 224
DP  - 2021 Mar 1
TI  - Covalent coupling fabrication of microporous organic network bonded capillary 
      columns for gas chromatographic separation.
PG  - 121914
LID - S0039-9140(20)31205-4 [pii]
LID - 10.1016/j.talanta.2020.121914 [doi]
AB  - Microporous organic networks (MONs) have shown great promise in separation 
      science recently. Exploring novel, simple and convenient strategy to fabricate 
      MONs coated capillary columns for gas chromatography (GC) still remains 
      challenging but desirable for the development of MONs in chromatographic 
      separation. To extend the potential application of MONs in separation science and 
      to further develop novel method for the fabrication of MONs-based capillary 
      columns, here we demonstrate a novel covalent coupling strategy to fabricate 
      uniform MONs bonded capillary columns for GC separation of position isomers and 
      hydrocarbons. The bare capillary column was firstly modified with 
      (3-bromopropyl)trimethoxysilane to provide bromine sites for coupling with 
      alkynyl monomers. The amino- and hydroxyl-functionalized MONs (MON-NH(2) and 
      MON-OH) were then directly grown onto the inner wall of the brominated capillary 
      columns via the covalent coupling between bromine and alkynyl groups. The uniform 
      MON-NH(2) and MON-OH bonded capillary columns were obtained and showed good 
      resolution for GC separation of dichlorobenzene, chlorotoluene, bromotoluene, and 
      propylbenzene position isomers and many other hydrocarbons including linear 
      alkanes, alkylbenzenes, pinene isomers, cyclohexane and benzene, ketones and 
      aldehydes. The MONs bonded capillary columns also owned good lifetime and 
      precision for dichlorobenzene isomers with the relative standard deviations 
      (RSDs) of 0.2-0.3%, 1.2-2.1%, and 1.7-2.5% for retention time, peak height and 
      peak area, respectively. In addition, the fabricated MON-NH(2) and MON-OH bonded 
      capillary columns offered better resolution than commercial InertCap-1, 
      InertCap-5, InertCap-1701 and InertCap-WAX capillary columns for the separation 
      of chlorotoluene and bromotoluene position isomers. These results revealed the 
      feasibility of covalent coupling strategy to fabricate MONs-based stationary 
      phases in GC, highlighting the potential of MONs in separation science.
CI  - Copyright (c) 2020 Elsevier B.V. All rights reserved.
FAU - Li, Xue
AU  - Li X
AD  - State Key Laboratory of Component-based Chinese Medicine, Tianjin State Key 
      Laboratory of Modern Chinese Medicine & Tianjin Key Laboratory of TCM Chemistry 
      and Analysis, Tianjin University of Traditional Chinese Medicine, Tianjin, 
      301617, China.
FAU - Cui, Yuan-Yuan
AU  - Cui YY
AD  - College of Chemistry, Research Center for Analytical Science, Tianjin Key 
      Laboratory of Biosensing and Molecular Recognition, Nankai University, Tianjin, 
      300071, China.
FAU - Yang, Cheng-Xiong
AU  - Yang CX
AD  - College of Chemistry, Research Center for Analytical Science, Tianjin Key 
      Laboratory of Biosensing and Molecular Recognition, Nankai University, Tianjin, 
      300071, China. Electronic address: cxyang@nankai.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20201123
PL  - Netherlands
TA  - Talanta
JT  - Talanta
JID - 2984816R
SB  - IM
OTO - NOTNLM
OT  - Covalent coupling
OT  - Gas chromatography
OT  - Microporous organic network
OT  - Position isomer
EDAT- 2021/01/01 06:00
MHDA- 2021/01/01 06:01
CRDT- 2020/12/31 01:01
PHST- 2020/09/30 00:00 [received]
PHST- 2020/11/12 00:00 [revised]
PHST- 2020/11/19 00:00 [accepted]
PHST- 2020/12/31 01:01 [entrez]
PHST- 2021/01/01 06:00 [pubmed]
PHST- 2021/01/01 06:01 [medline]
AID - S0039-9140(20)31205-4 [pii]
AID - 10.1016/j.talanta.2020.121914 [doi]
PST - ppublish
SO  - Talanta. 2021 Mar 1;224:121914. doi: 10.1016/j.talanta.2020.121914. Epub 2020 Nov 
      23.