PMID- 33380979
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220419
IS  - 1556-3316 (Print)
IS  - 1556-3324 (Electronic)
IS  - 1556-3316 (Linking)
VI  - 16
IP  - Suppl 2
DP  - 2020 Dec
TI  - Validating the VR-12 Physical Function Instrument After Anterior Cervical 
      Discectomy and Fusion with SF-12, PROMIS, and NDI.
PG  - 443-451
LID - 10.1007/s11420-020-09817-w [doi]
AB  - BACKGROUND: Development and validation of Veterans RAND 12-item (VR-12) physical 
      component survey (PCS) has been established among civilian and veteran 
      populations but it has not been examined among anterior cervical discectomy and 
      fusion (ACDF) patients. PURPOSES/QUESTIONS: We sought to validate legacy 
      patient-reported outcome measures (PROMs) with VR-12 PCS among patients 
      undergoing ACDF procedures. METHODS: A prospectively collected surgical registry 
      was retrospectively evaluated for elective single or multi-level ACDFs performed 
      for degenerative spinal pathologies from January 2014 to August 2019. Exclusion 
      criteria included missing pre-operative surveys and surgery for trauma, 
      metastasis, or infection. Demographic variables, baseline pathologies, and 
      peri-operative variables were collected. A paired t test evaluated the change 
      from the pre-operative score to each post-operative timepoint for VR-12 PCS, the 
      12-item Short-Form Survey (SF-12) PCS, Patient-Reported Outcomes 
      Measurement Information System physical function (PROMIS-PF), and Neck Disability 
      Index (NDI). Minimal clinically important difference (MCID) achievement was 
      calculated at each timepoint. Correlation was evaluated with a Pearson's 
      correlation coefficient and time-independent partial correlation. RESULTS: Of the 
      202 patients who underwent ACDF, 41.1% were female and the average age was 
      49.5 years. All PROMs had statistically significantly increased from baseline 
      when compared with post-operative timepoints (12 weeks, 6 months, 1 year, and 
      2 years). MCID achievement rates increased through 2 years. All timepoints 
      revealed strong VR-12 PCS correlations with SF-12 PCS, PROMIS-PF, and NDI scores. 
      CONCLUSION: VR-12 PCS was strongly correlated with the well-validated SF-12 PCS 
      and NDI metrics as well as with the more recent PROMIS-PF. All PROMs demonstrated 
      statistically significant improvement in patients post-operatively. VR-12 PCS is 
      a valid measure of physical function among patients undergoing ACDF.
CI  - (c) Hospital for Special Surgery 2020.
FAU - Jenkins, Nathaniel W
AU  - Jenkins NW
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. 
      Harrison St. Suite #300, Chicago, IL 60612 USA. GRID: grid.240684.c. ISNI: 0000 
      0001 0705 3621
FAU - Parrish, James M
AU  - Parrish JM
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. 
      Harrison St. Suite #300, Chicago, IL 60612 USA. GRID: grid.240684.c. ISNI: 0000 
      0001 0705 3621
FAU - Nolte, Michael T
AU  - Nolte MT
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. 
      Harrison St. Suite #300, Chicago, IL 60612 USA. GRID: grid.240684.c. ISNI: 0000 
      0001 0705 3621
FAU - Hrynewycz, Nadia M
AU  - Hrynewycz NM
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. 
      Harrison St. Suite #300, Chicago, IL 60612 USA. GRID: grid.240684.c. ISNI: 0000 
      0001 0705 3621
FAU - Brundage, Thomas S
AU  - Brundage TS
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. 
      Harrison St. Suite #300, Chicago, IL 60612 USA. GRID: grid.240684.c. ISNI: 0000 
      0001 0705 3621
FAU - Singh, Kern
AU  - Singh K
AUID- ORCID: 0000-0002-6118-7273
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. 
      Harrison St. Suite #300, Chicago, IL 60612 USA. GRID: grid.240684.c. ISNI: 0000 
      0001 0705 3621
LA  - eng
PT  - Journal Article
DEP - 20201109
PL  - United States
TA  - HSS J
JT  - HSS journal : the musculoskeletal journal of Hospital for Special Surgery
JID - 101273938
PMC - PMC7749899
OTO - NOTNLM
OT  - ACDF
OT  - anterior cervical discectomy and fusion
OT  - cervical surgery
OT  - patient-reported outcomes
OT  - physical function
COIS- Conflict of InterestNathaniel W. Jenkins, MS, James M. Parrish, MPH, Michael T. 
      Nolte, MD, Nadia M. Hrynewycz, BS, and Thomas S. Brundage, BS, declare that they 
      have no conflicts of interest. Kern Singh, MD, reports personal fees and 
      royalties from Zimmer Biomet, royalties from Stryker, RTI Surgical, and 
      Lippincott Williams and Wilkins, stock ownership from Avaz Surgical LLC, stock 
      ownership and board membership from Vital 5 LLC, personal fees from K2M, 
      non-financial support and board membership from TDi LLC, non-financial support 
      from Minimally Invasive Spine Study Group, Contemporary Spine Surgery, 
      Orthopedics Today, and Vertebral Columns, and grants from Cervical Spine Research 
      Society, outside the submitted work.
EDAT- 2021/01/01 06:00
MHDA- 2021/01/01 06:01
PMCR- 2021/12/01
CRDT- 2020/12/31 05:24
PHST- 2020/04/15 00:00 [received]
PHST- 2020/09/29 00:00 [accepted]
PHST- 2020/12/31 05:24 [entrez]
PHST- 2021/01/01 06:00 [pubmed]
PHST- 2021/01/01 06:01 [medline]
PHST- 2021/12/01 00:00 [pmc-release]
AID - 9817 [pii]
AID - 10.1007/s11420-020-09817-w [doi]
PST - ppublish
SO  - HSS J. 2020 Dec;16(Suppl 2):443-451. doi: 10.1007/s11420-020-09817-w. Epub 2020 
      Nov 9.