PMID- 33380992
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220419
IS  - 1556-3316 (Print)
IS  - 1556-3324 (Electronic)
IS  - 1556-3316 (Linking)
VI  - 16
IP  - Suppl 2
DP  - 2020 Dec
TI  - Reporting Clinical Significance in Hip Arthroscopy: Where Are We Now?
PG  - 527-533
LID - 10.1007/s11420-020-09759-3 [doi]
AB  - BACKGROUND: Although p values are standard for reporting statistical significance 
      of patient-reported outcome measures (PROMs), the shift toward clinically 
      important outcome values, including minimal clinically important difference 
      (MCID) and substantial clinical benefit (SCB), necessitates re-evaluation of the 
      current literature. QUESTIONS/PURPOSES: We sought to answer two questions 
      regarding studies on primary hip arthroscopy performed for the treatment of 
      femoroacetabular impingement syndrome (FAIS). (1) Do such studies reporting 
      statistical significance on common PROMs meet published MCID/SCB thresholds? (2) 
      What proportion of such studies report both statistical and clinical 
      significance? METHODS: We identified four papers published in two journals 
      defining MCID/SCB values on the modified Harris Hip Score (mHHS), Hip Outcome 
      Score-Activities of Daily Living (HOS-ADL), Hip Outcome Score-Sport (HOS-Sport), 
      international Hip Outcome Tool (iHOT-33), and its short version (iHOT-12) for 
      different groups of FAIS patients undergoing hip arthroscopy. We reviewed these 
      two journals from the dates of publication to the present to identify papers 
      reporting changes in post-operative PROMs. The difference in pre- and 
      post-operative scores on each PROM was calculated and compared to MCID/SCB 
      thresholds. RESULTS: Twelve studies were included. Ten studies (83%) evaluated 
      mHHS (90% met MCID, 50% met SCB), seven (58%) evaluated HOS-ADL (100% met 
      MCID/SCB) and HOS-Sport (100% met MCID, 57% met SCB), and one (8%) evaluated 
      iHOT-33 (met MCID/SCB) and iHOT-12 (met MCID). Most studies met MCID and SCB at 
      both 1- and 2-year timepoints. Of the studies evaluated, 50% reported clinical 
      relevance. CONCLUSIONS: Nearly all studies evaluated met MCID, while fewer met 
      SCB. Only half discussed these clinical measures. It is proposed that all future 
      studies report both statistical and clinical significance as standard best 
      practice.
CI  - (c) Hospital for Special Surgery 2020.
FAU - Polascik, Breanna A
AU  - Polascik BA
AD  - Hospital for Special Surgery, Healthcare Research Institute, 535 East 70th 
      Street, New York, NY 10021 USA. GRID: grid.239915.5. ISNI: 0000 0001 2285 8823
FAU - Peck, Jeffrey
AU  - Peck J
AD  - Hospital for Special Surgery, Sports Medicine Institute, New York, NY 10021 USA. 
      GRID: grid.239915.5. ISNI: 0000 0001 2285 8823
FAU - Cepeda, Nicholas
AU  - Cepeda N
AD  - Hospital for Special Surgery, Sports Medicine Institute, New York, NY 10021 USA. 
      GRID: grid.239915.5. ISNI: 0000 0001 2285 8823
FAU - Lyman, Stephen
AU  - Lyman S
AD  - Hospital for Special Surgery, Healthcare Research Institute, 535 East 70th 
      Street, New York, NY 10021 USA. GRID: grid.239915.5. ISNI: 0000 0001 2285 8823
AD  - Department of Healthcare Policy and Research, Weill Cornell Medical College, New 
      York, NY 10021 USA. GRID: grid.5386.8. ISNI: 000000041936877X
FAU - Ling, Daphne
AU  - Ling D
AD  - Hospital for Special Surgery, Sports Medicine Institute, New York, NY 10021 USA. 
      GRID: grid.239915.5. ISNI: 0000 0001 2285 8823
AD  - Department of Healthcare Policy and Research, Weill Cornell Medical College, New 
      York, NY 10021 USA. GRID: grid.5386.8. ISNI: 000000041936877X
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20200412
PL  - United States
TA  - HSS J
JT  - HSS journal : the musculoskeletal journal of Hospital for Special Surgery
JID - 101273938
PMC - PMC7749910
OTO - NOTNLM
OT  - femoroacetabular impingement syndrome
OT  - hip arthroscopy
OT  - minimal clinically important difference
OT  - patient-reported outcome measures
OT  - substantial clinical benefit
COIS- Conflict of InterestBreanna A. Polascik, BS, Jeffrey Peck, MD, Nicholas Cepeda, 
      BS, and Daphne Ling PhD, declare that they have no conflicts of interest. Stephen 
      Lyman, PhD, reports grants from National Institutes of Health/National Institute 
      of Arthritis and Musculoskeletal and Skin Diseases, as well as personal fees from 
      Journal of Bone and Joint Surgery, Japanese Orthopaedic Society of Knee, 
      Arthroscopy, and Sports Medicine, Omni, Inc., and Universal Research Solutions, 
      outside the submitted work.
EDAT- 2021/01/01 06:00
MHDA- 2021/01/01 06:01
PMCR- 2021/12/01
CRDT- 2020/12/31 05:24
PHST- 2019/12/31 00:00 [received]
PHST- 2020/03/12 00:00 [accepted]
PHST- 2020/12/31 05:24 [entrez]
PHST- 2021/01/01 06:00 [pubmed]
PHST- 2021/01/01 06:01 [medline]
PHST- 2021/12/01 00:00 [pmc-release]
AID - 9759 [pii]
AID - 10.1007/s11420-020-09759-3 [doi]
PST - ppublish
SO  - HSS J. 2020 Dec;16(Suppl 2):527-533. doi: 10.1007/s11420-020-09759-3. Epub 2020 
      Apr 12.