PMID- 33384404
OWN - NLM
STAT- MEDLINE
DCOM- 20210520
LR  - 20210520
IS  - 1643-3750 (Electronic)
IS  - 1234-1010 (Print)
IS  - 1234-1010 (Linking)
VI  - 27
DP  - 2021 Jan 1
TI  - Comparison of Oncoplastic Breast-Conserving Therapy and Standard 
      Breast-Conserving Therapy in Early-Stage Breast Cancer Patients.
PG  - e927015
LID - 10.12659/MSM.927015 [doi]
AB  - BACKGROUND The aim of this study was to compare the efficacy and safety of 
      oncoplastic breast-conserving therapy (OBCT) and SBCT (standard breast-conserving 
      therapy) in breast cancer surgery. MATERIAL AND METHODS We enrolled 192 breast 
      cancer patients who underwent breast-conserving surgery during January 2015 to 
      April 2018. The surgery strategies of OBCT and SBCT were performed according to 
      the patients' condition. For measurement of surgical cosmetic effects, the Harris 
      scale, the modified objective scores, and the subjective evaluation were all 
      used. The basic clinical characteristics, intraoperative indices, postoperative 
      complications, metastasis, and recurrence during the 2-year follow-up were 
      recorded. RESULTS The mean surgical time was remarkably longer and the resected 
      volume was markedly larger in the OBCT group than in the SBCT group. The 
      excellent and good ratios of Harris scale, the modified objective scores, and the 
      ratio of very satisfied and satisfied patients by subjective scale were all 
      significantly higher in the OBCT group than in the SBCT group. The occurrence 
      rates of seroma and poor incision healing were remarkably lower in the OBCT 
      group. No significant difference was found for metastasis and recurrence. 
      CONCLUSIONS OBCT had better cosmetic effects, fewer complications, and no adverse 
      effects on metastasis and recurrence.
FAU - Zhou, Yuan
AU  - Zhou Y
AD  - Department of General Surgery, The Affiliated Hospital of Jiaxing University and 
      The First Hospital of Jiaxing, Jiaxing, Zhejiang, China (mainland).
FAU - Liu, Yixiao
AU  - Liu Y
AD  - Department of Stomatology, The Affiliated Hospital of Jiaxing University and The 
      First Hospital of Jiaxing, Jiaxing, Zhejiang, China (mainland).
FAU - Wang, Yu
AU  - Wang Y
AD  - Department of Burn and Plastic Surgery, The Affiliated Hospital of Jiaxing 
      University and The First Hospital of Jiaxing, Jiaxing, Zhejiang, China 
      (mainland).
FAU - Wu, Yanfei
AU  - Wu Y
AD  - College of Foreign Studies, Jiaxing University Jiaxing, Jiaxing, Zhejiang, China 
      (mainland).
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20210101
PL  - United States
TA  - Med Sci Monit
JT  - Medical science monitor : international medical journal of experimental and 
      clinical research
JID - 9609063
SB  - IM
MH  - Breast Neoplasms/*pathology/*surgery
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Intraoperative Care
MH  - Kaplan-Meier Estimate
MH  - *Mastectomy, Segmental/adverse effects
MH  - Middle Aged
MH  - Neoplasm Metastasis
MH  - Neoplasm Recurrence, Local/pathology
MH  - Neoplasm Staging
MH  - Postoperative Care
MH  - Postoperative Complications/etiology
MH  - Reference Standards
MH  - Surgery, Plastic
PMC - PMC7784144
COIS- Conflicts of interest None.
EDAT- 2021/01/02 06:00
MHDA- 2021/05/21 06:00
PMCR- 2020/01/01
CRDT- 2021/01/01 05:17
PHST- 2021/01/01 05:17 [entrez]
PHST- 2021/01/02 06:00 [pubmed]
PHST- 2021/05/21 06:00 [medline]
PHST- 2020/01/01 00:00 [pmc-release]
AID - 927015 [pii]
AID - 10.12659/MSM.927015 [doi]
PST - epublish
SO  - Med Sci Monit. 2021 Jan 1;27:e927015. doi: 10.12659/MSM.927015.