PMID- 33388322 OWN - NLM STAT- MEDLINE DCOM- 20210625 LR - 20220109 IS - 1096-0260 (Electronic) IS - 0091-7435 (Linking) VI - 144 DP - 2021 Mar TI - HPV vaccination introduction worldwide and WHO and UNICEF estimates of national HPV immunization coverage 2010-2019. PG - 106399 LID - S0091-7435(20)30430-8 [pii] LID - 10.1016/j.ypmed.2020.106399 [doi] AB - WHO/UNICEF estimates for HPV vaccination coverage from 2010 to 2019 are analyzed against the backdrop of the 90% coverage target for HPV vaccination by 2030 set in the recently approved global strategy for cervical cancer elimination as a public health problem. As of June 2020, 107 (55%) of the 194 WHO Member States have introduced HPV vaccination. The Americas and Europe are by far the WHO regions with the most introductions, 85% and 77% of their countries having already introduced respectively. A record number of introductions was observed in 2019, most of which in low- and middle- income countries (LMIC) where access has been limited. Programs had an average performance coverage of around 67% for the first dose and 53% for the final dose of HPV. LMICs performed on average better than high- income countries for the first dose, but worse for the last dose due to higher dropout. Only 5 (6%) countries achieved coverages with the final dose of more than 90%, 22 countries (21%) achieved coverages of 75% or higher while 35 (40%) had a final dose coverage of 50% or less. When expressed as world population coverage (i.e., weighted by population size), global coverage of the final HPV dose for 2019 is estimated at 15%. There is a long way to go to meet the 2030 elimination target of 90%. In the post-COVID era attention should be paid to maintain the pace of introductions, specially ensuring the most populous countries introduce, and further improving program performance globally. CI - Copyright (c) 2020. Published by Elsevier Inc. FAU - Bruni, Laia AU - Bruni L AD - Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO) - IDIBELL, l'Hospitalet de Llobregat, Spain; Centro de Investigacion Biomedica en Red: Epidemiologia y Salud Publica (CIBERESP CB06/02/0073), Madrid, Spain. Electronic address: lbruni@iconcologia.net. FAU - Saura-Lazaro, Anna AU - Saura-Lazaro A AD - Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO) - IDIBELL, l'Hospitalet de Llobregat, Spain. Electronic address: asaura.lazaro@iconcologia.net. FAU - Montoliu, Alexandra AU - Montoliu A AD - Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO) - IDIBELL, l'Hospitalet de Llobregat, Spain. Electronic address: amontoliu@iconcologia.net. FAU - Brotons, Maria AU - Brotons M AD - Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO) - IDIBELL, l'Hospitalet de Llobregat, Spain; Centro de Investigacion Biomedica en Red: Epidemiologia y Salud Publica (CIBERESP CB06/02/0073), Madrid, Spain. Electronic address: mbrotons@iconcologia.net. FAU - Alemany, Laia AU - Alemany L AD - Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO) - IDIBELL, l'Hospitalet de Llobregat, Spain; Centro de Investigacion Biomedica en Red: Epidemiologia y Salud Publica (CIBERESP CB06/02/0073), Madrid, Spain. Electronic address: lalemany@iconcologia.net. FAU - Diallo, Mamadou Saliou AU - Diallo MS AD - Data and Analytics Unit, Department of Analysis, Planning & Monitoring, UNICEF, New York, USA. Electronic address: mamsdiallo@unicef.org. FAU - Afsar, Oya Zeren AU - Afsar OZ AD - Maternal, Neonatal & Adolescent Health Unit, Health Section, UNICEF, New York, USA. Electronic address: oafsar@unicef.org. FAU - LaMontagne, D Scott AU - LaMontagne DS AD - Center for Vaccine Innovation and Access, PATH, Seattle, USA. Electronic address: slamontagne@path.org. FAU - Mosina, Liudmila AU - Mosina L AD - Division of Country Health Programmes, Vaccine-preventable Diseases and Immunization (VPI), World Health Organization Regional Office for the Europe, Copenhagen, Denmark. Electronic address: mosinal@who.int. FAU - Contreras, Marcela AU - Contreras M AD - Comprehensive Family Immunization Unit, Pan American Health Organization, PAHO/WHO, Washington, DC, USA. Electronic address: contrermar@paho.org. FAU - Velandia-Gonzalez, Martha AU - Velandia-Gonzalez M AD - Comprehensive Family Immunization Unit, Pan American Health Organization, PAHO/WHO, Washington, DC, USA. Electronic address: velandiam@paho.org. FAU - Pastore, Roberta AU - Pastore R AD - Division of Country Health Programmes, Vaccine-preventable Diseases and Immunization (VPI), World Health Organization Regional Office for the Europe, Copenhagen, Denmark. Electronic address: pastorero@who.int. FAU - Gacic-Dobo, Marta AU - Gacic-Dobo M AD - Immunization Analysis & Insights Vaccines and Biologicals, World Health Organization, Geneva, Switzerland,. Electronic address: gacicdobom@who.int. FAU - Bloem, Paul AU - Bloem P AD - Life Course and Integration/ EPI, Department of Immunization, Vaccines and Biologicals, World Health Organization, Geneva, Switzerland. Electronic address: bloemp@who.int. LA - eng GR - 001/WHO_/World Health Organization/International PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20201231 PL - United States TA - Prev Med JT - Preventive medicine JID - 0322116 RN - 0 (Papillomavirus Vaccines) SB - IM EIN - Prev Med. 2022 Feb;155:106925. PMID: 34998610 MH - *COVID-19 MH - Europe MH - Female MH - Humans MH - Immunization Programs MH - *Papillomavirus Infections/prevention & control MH - *Papillomavirus Vaccines MH - SARS-CoV-2 MH - United Nations MH - *Uterine Cervical Neoplasms/prevention & control MH - Vaccination MH - Vaccination Coverage MH - World Health Organization EDAT- 2021/01/04 06:00 MHDA- 2021/06/29 06:00 CRDT- 2021/01/03 20:26 PHST- 2020/08/24 00:00 [received] PHST- 2020/12/28 00:00 [revised] PHST- 2020/12/29 00:00 [accepted] PHST- 2021/01/04 06:00 [pubmed] PHST- 2021/06/29 06:00 [medline] PHST- 2021/01/03 20:26 [entrez] AID - S0091-7435(20)30430-8 [pii] AID - 10.1016/j.ypmed.2020.106399 [doi] PST - ppublish SO - Prev Med. 2021 Mar;144:106399. doi: 10.1016/j.ypmed.2020.106399. Epub 2020 Dec 31.