PMID- 33396861
OWN - NLM
STAT- MEDLINE
DCOM- 20210907
LR  - 20210907
IS  - 2072-6643 (Electronic)
IS  - 2072-6643 (Linking)
VI  - 13
IP  - 1
DP  - 2020 Dec 30
TI  - The Mediterranean Diet Benefit on Cardiovascular Hemodynamics and Erectile 
      Function in Chronic Heart Failure Male Patients by Decoding Central and 
      Peripheral Vessel Rheology.
LID - 10.3390/nu13010108 [doi]
LID - 108
AB  - BACKGROUND: Mediterranean diet was evaluated on erectile performance and 
      cardiovascular hemodynamics, in chronic heart failure patients. METHODS: 150 male 
      stable heart failure patients were enrolled in the study (62 +/- 10 years, New York 
      Heart Association (NYHA) classes I-II, ejection fraction </=40%). A detailed 
      echocardiographic evaluation including estimation of the global longitudinal 
      strain of the left ventricle and the systolic tissue doppler velocity of the 
      tricuspid annulus was performed. Erectile dysfunction severity was assessed by 
      the Sexual Health Inventory for Men-5 (SHIM-5) score. Adherence to the 
      Mediterranean diet was evaluated by the MedDietScore. RESULTS: The SHIM-5 score 
      was positively correlated with the MedDietScore (p = 0.006) and augmentation 
      index (p = 0.031) and inversely correlated with age (p = 0.002). MedDietScore was 
      negatively associated with intima-media-thickness (p < 0.001) and serum prolactin 
      levels (p = 0.05). Multi-adjusted analysis revealed that the inverse relation of 
      SHIM-5 and prolactin levels remained significant only among patients with low 
      adherence to the Mediterranean diet (p = 0.012). CONCLUSION: Consumption of 
      Mediterranean diet benefits cardiovascular hemodynamics, while suppressing serum 
      prolactin levels. Such physiology may enhance erectile ability independently of 
      the of the left ventricle ejection fraction.
FAU - Angelis, Athanasios
AU  - Angelis A
AD  - First Cardiology Clinic, Hippokration Hospital, School of Medicine, University of 
      Athens, 11527 Athens, Greece.
FAU - Chrysohoou, Christina
AU  - Chrysohoou C
AUID- ORCID: 0000-0002-6340-3996
AD  - First Cardiology Clinic, Hippokration Hospital, School of Medicine, University of 
      Athens, 11527 Athens, Greece.
FAU - Tzorovili, Evangelia
AU  - Tzorovili E
AUID- ORCID: 0000-0001-7051-5286
AD  - First Cardiology Clinic, Hippokration Hospital, School of Medicine, University of 
      Athens, 11527 Athens, Greece.
FAU - Laina, Aggeliki
AU  - Laina A
AD  - First Cardiology Clinic, Hippokration Hospital, School of Medicine, University of 
      Athens, 11527 Athens, Greece.
FAU - Xydis, Panagiotis
AU  - Xydis P
AD  - First Cardiology Clinic, Hippokration Hospital, School of Medicine, University of 
      Athens, 11527 Athens, Greece.
FAU - Terzis, Ioannis
AU  - Terzis I
AD  - First Cardiology Clinic, Hippokration Hospital, School of Medicine, University of 
      Athens, 11527 Athens, Greece.
FAU - Ioakeimidis, Nikos
AU  - Ioakeimidis N
AD  - First Cardiology Clinic, Hippokration Hospital, School of Medicine, University of 
      Athens, 11527 Athens, Greece.
FAU - Aznaouridis, Konstantinos
AU  - Aznaouridis K
AD  - First Cardiology Clinic, Hippokration Hospital, School of Medicine, University of 
      Athens, 11527 Athens, Greece.
FAU - Vlachopoulos, Charalambos
AU  - Vlachopoulos C
AD  - First Cardiology Clinic, Hippokration Hospital, School of Medicine, University of 
      Athens, 11527 Athens, Greece.
FAU - Tsioufis, Konstantinos
AU  - Tsioufis K
AD  - First Cardiology Clinic, Hippokration Hospital, School of Medicine, University of 
      Athens, 11527 Athens, Greece.
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
DEP - 20201230
PL  - Switzerland
TA  - Nutrients
JT  - Nutrients
JID - 101521595
RN  - 9002-62-4 (Prolactin)
SB  - IM
MH  - Aged
MH  - *Carotid Intima-Media Thickness
MH  - Chronic Disease
MH  - *Diet, Mediterranean
MH  - *Echocardiography
MH  - *Heart Failure/blood/diagnostic imaging/diet therapy/physiopathology
MH  - *Hemorheology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Penile Erection
MH  - Prolactin/*blood
PMC - PMC7824543
OTO - NOTNLM
OT  - chronic heart failure
OT  - erectile function
OT  - mediterranean diet
OT  - prolactin
COIS- The authors declare no conflict of interest.
EDAT- 2021/01/06 06:00
MHDA- 2021/09/08 06:00
PMCR- 2020/12/30
CRDT- 2021/01/05 01:18
PHST- 2020/11/11 00:00 [received]
PHST- 2020/12/20 00:00 [revised]
PHST- 2020/12/27 00:00 [accepted]
PHST- 2021/01/05 01:18 [entrez]
PHST- 2021/01/06 06:00 [pubmed]
PHST- 2021/09/08 06:00 [medline]
PHST- 2020/12/30 00:00 [pmc-release]
AID - nu13010108 [pii]
AID - nutrients-13-00108 [pii]
AID - 10.3390/nu13010108 [doi]
PST - epublish
SO  - Nutrients. 2020 Dec 30;13(1):108. doi: 10.3390/nu13010108.