PMID- 33400109
OWN - NLM
STAT- MEDLINE
DCOM- 20210331
LR  - 20210331
IS  - 1614-7499 (Electronic)
IS  - 0944-1344 (Linking)
VI  - 28
IP  - 14
DP  - 2021 Apr
TI  - Dissipation kinetics and safety evaluation of pyraclostrobin and its desmethoxy 
      metabolite BF 500-3 in a cucumber greenhouse agroecosystem.
PG  - 17712-17723
LID - 10.1007/s11356-020-11798-6 [doi]
AB  - Pyraclostrobin (PYR), a fungicide of the strobilurin class, is used to control 
      many different kinds of fungal diseases in greenhouses and on agricultural 
      fields. In the present study, an efficient method was established for 
      simultaneously determining PYR and its metabolite BF 500-3 in cucumber fruits, 
      leaves, and soil matrices using QuEChERS pretreatment coupled with 
      ultra-high-performance liquid chromatography-tandem mass spectrometry 
      (UHPLC-MS/MS). The residue levels and dissipation kinetics of PYR were determined 
      under greenhouse conditions. The recoveries ranged from 89.8 to 103.6% with 
      relative standard deviations (RSDs) of 3.6-7.5% at three spiking levels. The 
      results demonstrated that PYR dissipated quickly in the cucumber field with 
      half-lives (DT(50)) of 2.14-4.17 days on different sites and in different 
      matrices. The residue of its metabolite BF 500-3 was very low and showed a trend 
      of first increasing and then decreasing. The degradation rate of PYR in soil was 
      the fastest, followed by that on cucumber fruits and leaves. The terminal residue 
      of PYR at an application rate of 150 g a.i. ha(-1) (the maximum recommended rate) 
      in cucumber fruits was below the maximum residue limit (MRL) of 0.5 mg/kg 
      established in China. However, the application of the fungicide at 225 g a.i. 
      ha(-1) (1.5x the maximum recommended rate) resulted in residues that were above 
      the MRL 1 day after the final application, which is an unacceptable risk. 
      Therefore, the application dosage of PYR at the recommended rates was safe to 
      human beings and animals.
FAU - He, Lifei
AU  - He L
AD  - Key Laboratory of Pesticide Toxicology and Application Technique, College of 
      Plant Protection, Shandong Agricultural University, Tai'an,, Shandong, 271018, 
      People's Republic of China.
FAU - He, Falin
AU  - He F
AD  - Key Laboratory of Pesticide Toxicology and Application Technique, College of 
      Plant Protection, Shandong Agricultural University, Tai'an,, Shandong, 271018, 
      People's Republic of China.
FAU - Yang, Song
AU  - Yang S
AD  - Research Center of Pesticide Environmental Toxicology, Shandong Agricultural 
      University, Tai'an, Shandong, 271018, People's Republic of China.
FAU - Gao, Yangyang
AU  - Gao Y
AD  - Key Laboratory of Pesticide Toxicology and Application Technique, College of 
      Plant Protection, Shandong Agricultural University, Tai'an,, Shandong, 271018, 
      People's Republic of China.
FAU - Li, Beixing
AU  - Li B
AD  - Key Laboratory of Pesticide Toxicology and Application Technique, College of 
      Plant Protection, Shandong Agricultural University, Tai'an,, Shandong, 271018, 
      People's Republic of China.
FAU - Liu, Feng
AU  - Liu F
AD  - Key Laboratory of Pesticide Toxicology and Application Technique, College of 
      Plant Protection, Shandong Agricultural University, Tai'an,, Shandong, 271018, 
      People's Republic of China.
AD  - Research Center of Pesticide Environmental Toxicology, Shandong Agricultural 
      University, Tai'an, Shandong, 271018, People's Republic of China.
FAU - Mu, Wei
AU  - Mu W
AD  - Key Laboratory of Pesticide Toxicology and Application Technique, College of 
      Plant Protection, Shandong Agricultural University, Tai'an,, Shandong, 271018, 
      People's Republic of China. muwei@sdau.edu.cn.
AD  - Research Center of Pesticide Environmental Toxicology, Shandong Agricultural 
      University, Tai'an, Shandong, 271018, People's Republic of China. 
      muwei@sdau.edu.cn.
LA  - eng
GR  - 2017YFD0200307/National Key Research Development Program of China/
GR  - 2017YFD0201901/National Key Research Development Program of China/
PT  - Journal Article
DEP - 20210105
PL  - Germany
TA  - Environ Sci Pollut Res Int
JT  - Environmental science and pollution research international
JID - 9441769
RN  - 0 (Pesticide Residues)
RN  - 0 (Soil Pollutants)
RN  - 0 (Strobilurins)
RN  - DJW8M9OX1H (pyrachlostrobin)
SB  - IM
MH  - China
MH  - *Cucumis sativus
MH  - Half-Life
MH  - Humans
MH  - Kinetics
MH  - *Pesticide Residues/analysis
MH  - *Soil Pollutants/analysis
MH  - Strobilurins/analysis
MH  - Tandem Mass Spectrometry
OTO - NOTNLM
OT  - Cucumber
OT  - Dissipation kinetics
OT  - Metabolite
OT  - Pyraclostrobin
OT  - QuEChERS
OT  - UHPLC-MS/MS
EDAT- 2021/01/06 06:00
MHDA- 2021/04/01 06:00
CRDT- 2021/01/05 12:16
PHST- 2020/06/18 00:00 [received]
PHST- 2020/11/23 00:00 [accepted]
PHST- 2021/01/06 06:00 [pubmed]
PHST- 2021/04/01 06:00 [medline]
PHST- 2021/01/05 12:16 [entrez]
AID - 10.1007/s11356-020-11798-6 [pii]
AID - 10.1007/s11356-020-11798-6 [doi]
PST - ppublish
SO  - Environ Sci Pollut Res Int. 2021 Apr;28(14):17712-17723. doi: 
      10.1007/s11356-020-11798-6. Epub 2021 Jan 5.