PMID- 33409107
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210111
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 12
IP  - 12
DP  - 2020 Dec 31
TI  - Colon Capsule Endoscopy in Detecting Colonic Diverticula in a Japanese 
      Population.
PG  - e12393
LID - 10.7759/cureus.12393 [doi]
LID - e12393
AB  - Objective The assessment of colonic diverticula with colon capsule endoscopy 
      (CCE) in a Japanese population provided unclear results. In this study, we 
      retrospectively reviewed a cohort of Japanese patients who had undergone CCE to 
      assess its safety and usefulness in the diagnosis of colonic diverticula. Methods 
      In this study, 175 consecutive Japanese patients who had their entire colon 
      observed via CCE from November 2013 to July 2018 were included. Patients were 
      retrospectively stratified according to age, gender, colonic segment, and 
      symptoms involvement. A multivariable regression analysis was performed to 
      investigate the presence of any correlation among variables. The safety of CCE 
      was assessed in terms of the incidence of adverse events (AEs). Results Colonic 
      diverticula were observed in 42.3% of all cases; of those; 36.5% were 
      right-sided, 31.1% were left-sided, and 32.4% were bilateral. Moreover, one to 
      two colonic diverticula were observed in 35.1%, while three or more diverticula 
      were seen in 64.9%. Multivariable analysis showed that age (>/=70 years) was 
      positively associated with colonic diverticula, while male gender and the 
      presence of colonic polyps were negatively associated with colonic diverticula. 
      No correlation was found between colonic diverticula and symptoms. There was no 
      significant difference between groups with and without colonic diverticula in the 
      incidence of AEs. AEs were mild in severity, with no severe AE-related bowel 
      preparation and capsule ingestion reported. Conclusion CCE was well-tolerated by 
      the participants, and the incidence of colonic diverticula was 42.3%, with one to 
      two and three or more diverticula being found in 35.1% and 64.9%, respectively. 
      There was little difference in the frequency of colonic diverticula formation on 
      the right side, left side, and on both sides. Age was a positive association 
      factor, while male gender and the presence of colorectal polyps were negative 
      association factors. No correlation was found between diverticula and symptoms.
CI  - Copyright (c) 2020, Nakaji et al.
FAU - Nakaji, Konosuke
AU  - Nakaji K
AD  - Internal Medicine: Gastroenterology, Endoscopy Center, Aishinkai Nakae Hospital, 
      Wakayama-Shi, JPN.
LA  - eng
PT  - Journal Article
DEP - 20201231
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC7779143
OTO - NOTNLM
OT  - colon capsule endoscopy
OT  - colonic diverticula
OT  - epidemiology
COIS- The authors have declared that no competing interests exist.
EDAT- 2021/01/08 06:00
MHDA- 2021/01/08 06:01
PMCR- 2020/12/31
CRDT- 2021/01/07 06:07
PHST- 2021/01/07 06:07 [entrez]
PHST- 2021/01/08 06:00 [pubmed]
PHST- 2021/01/08 06:01 [medline]
PHST- 2020/12/31 00:00 [pmc-release]
AID - 10.7759/cureus.12393 [doi]
PST - epublish
SO  - Cureus. 2020 Dec 31;12(12):e12393. doi: 10.7759/cureus.12393.