PMID- 33413367
OWN - NLM
STAT- MEDLINE
DCOM- 20210701
LR  - 20240330
IS  - 1746-6148 (Electronic)
IS  - 1746-6148 (Linking)
VI  - 17
IP  - 1
DP  - 2021 Jan 7
TI  - Epidemiological investigation of porcine circovirus type 2 and its coinfection 
      rate in Shandong province in China from 2015 to 2018.
PG  - 17
LID - 10.1186/s12917-020-02718-4 [doi]
LID - 17
AB  - BACKGROUND: Porcine circovirus type 2 (PCV2) is one of the crucial swine viral 
      pathogens, caused porcine circovirus associated diseases (PCVAD). Shandong 
      province is one of the most important pork producing areas and bears a 
      considerable economic loss due to PCVAD. However, there is limited information on 
      epidemiology and coinfection rate of PCV2 with other critical swine diseases in 
      this area, such as porcine reproductive and respiratory syndrome virus (PRRSV), 
      classical swine fever virus (CSFV), Pseudorabies virus (PRV), and porcine 
      epidemic diarrhea virus (PEDV). RESULTS: Overall, 89.59% serum samples and 36.98% 
      tissue samples were positive for PCV2 specified ELISA and PCR positive for PCV2, 
      respectively. The coinfection rates of PCV2 with PRRSV, PRV, CSFV, and PEDV were 
      26.73%, 18.37%, 13.06%, and 3.47%, respectively. Moreover, genetic characteristic 
      of PCV2 were analyzed based on the cap genes showing that PCV2d is the dominant 
      sub-genotype circulating in the province. CONCLUSIONS: Our findings reveal that 
      PCV2d, as the dominant strain, is prevailing in pig farms in Shandong province at 
      high levels. There was a high frequency of coinfection of PCV2 and PRRSV.
FAU - Ma, Zicheng
AU  - Ma Z
AD  - College of Animal Science and Veterinary Medicine, Shandong Agricultural 
      University, 271018, Taian, China.
FAU - Liu, Mengda
AU  - Liu M
AD  - Laboratory of Zoonoses, Animal Health and Epidemiology Center, 266032, Qingdao, 
      China.
FAU - Liu, Zhaohu
AU  - Liu Z
AD  - College of Animal Science and Veterinary Medicine, Shandong Agricultural 
      University, 271018, Taian, China.
FAU - Meng, Fanliang
AU  - Meng F
AD  - College of Animal Science and Veterinary Medicine, Shandong Agricultural 
      University, 271018, Taian, China.
FAU - Wang, Hongyu
AU  - Wang H
AD  - College of Animal Science and Veterinary Medicine, Shandong Agricultural 
      University, 271018, Taian, China.
FAU - Cao, Longlong
AU  - Cao L
AD  - College of Animal Science and Veterinary Medicine, Shandong Agricultural 
      University, 271018, Taian, China.
FAU - Li, Yan
AU  - Li Y
AD  - College of Animal Science and Veterinary Medicine, Shandong Agricultural 
      University, 271018, Taian, China.
FAU - Jiao, Qiulin
AU  - Jiao Q
AD  - College of Animal Science and Veterinary Medicine, Shandong Agricultural 
      University, 271018, Taian, China.
FAU - Han, Zifeng
AU  - Han Z
AD  - Emergency Centre for the Control of Transboundary Animal Diseases, Food and 
      Agriculture Organization of the United Nations (FAO), 100600, Beijing, China. 
      alex_hzf@hotmail.com.
FAU - Liu, Sidang
AU  - Liu S
AUID- ORCID: 0000-0001-8400-2764
AD  - College of Animal Science and Veterinary Medicine, Shandong Agricultural 
      University, 271018, Taian, China. liusid@sdau.edu.cn.
LA  - eng
GR  - 2017YFD0500600/National Key Research and Development Program of China/
PT  - Journal Article
DEP - 20210107
PL  - England
TA  - BMC Vet Res
JT  - BMC veterinary research
JID - 101249759
SB  - IM
MH  - Animals
MH  - China/epidemiology
MH  - Circoviridae Infections/epidemiology/*veterinary
MH  - Circovirus
MH  - Classical Swine Fever/*epidemiology
MH  - Classical Swine Fever Virus/physiology
MH  - Coinfection/epidemiology/*veterinary/virology
MH  - Coronavirus Infections/epidemiology/*veterinary
MH  - Herpesvirus 1, Suid/physiology
MH  - Porcine Reproductive and Respiratory Syndrome/*epidemiology
MH  - Porcine epidemic diarrhea virus/physiology
MH  - Porcine respiratory and reproductive syndrome virus/physiology
MH  - Pseudorabies/*epidemiology
MH  - Swine
MH  - Swine Diseases/*epidemiology/virology
PMC - PMC7792206
OTO - NOTNLM
OT  - Coinfection
OT  - Phylogenetic analysis
OT  - Porcine circovirus
OT  - Shandong province
OT  - Veterinary epidemiology
COIS- The authors declare that they have no competing interests.
EDAT- 2021/01/09 06:00
MHDA- 2021/07/02 06:00
PMCR- 2021/01/07
CRDT- 2021/01/08 05:44
PHST- 2020/05/22 00:00 [received]
PHST- 2020/12/09 00:00 [accepted]
PHST- 2021/01/08 05:44 [entrez]
PHST- 2021/01/09 06:00 [pubmed]
PHST- 2021/07/02 06:00 [medline]
PHST- 2021/01/07 00:00 [pmc-release]
AID - 10.1186/s12917-020-02718-4 [pii]
AID - 2718 [pii]
AID - 10.1186/s12917-020-02718-4 [doi]
PST - epublish
SO  - BMC Vet Res. 2021 Jan 7;17(1):17. doi: 10.1186/s12917-020-02718-4.