PMID- 33416011
OWN - NLM
STAT- MEDLINE
DCOM- 20220405
LR  - 20220405
IS  - 1532-4311 (Electronic)
IS  - 0882-0139 (Linking)
VI  - 51
IP  - 3
DP  - 2022 Apr
TI  - Evaluation of Serum Immunoreactivity to Common Indigenous Iranian Inhalation and 
      Food Allergens in Patients with Meniere's Disease.
PG  - 705-714
LID - 10.1080/08820139.2020.1869252 [doi]
AB  - BACKGROUND: A few studies investigated the relationship between allergy and 
      Meniere disease considering complete allergen panel. We aimed to evaluate the 
      serum immunoreactivity in patients with Meniere's disease (MD) compared with 
      healthy people according to common indigenous Iranian inhalation and food 
      allergens. METHODS: Thirty-nine patients with MD referred to Rasoul Akram 
      Hospital (Tehran, Iran) were evaluated and compared with a 41 membered control 
      group. A panel of common inhalation and food allergens (using an immunoblotting 
      method), as well as total immunoglobulin E (IgE) level (using the sandwich 
      enzyme-linked immunosorbent assay method), were checked on the patients' serum. 
      RESULTS: The mean total IgE level was 193.85 +/- 175.43 IU/ml in the patients with 
      MD and 117.61 +/- 138.05 IU/ml in the control group, which was significantly higher 
      than the other subjects in the control group (P = .016). There was a significant 
      difference between the two groups regarding inhalation allergens such as; sweet 
      vernal grass, cultivated rye, cultivated oat, Russian thistle, goosefoot, and 
      rough pigweed (P = .01-0.038). Patients with MD reported more reactive to food 
      allergens such as; rye flour, hazelnut, pepper, citrus mix 2, potato, strawberry, 
      and celery allergens. There was a significant relationship between Meniere and 
      serum immunoreactivity to inhalation and food allergens (both P 
      = .001).Conclusion: Serum total IgE level in patients with MD (in both inhalation 
      and food allergens groups) was higher than the control group, and there was a 
      relationship between MD and immunoreactivity to common indigenous inhalation and 
      food allergens of Iran.
FAU - Roomiani, Maryam
AU  - Roomiani M
AD  - ENT and Head and Neck Research Center, The Five Senses Health Institute, Iran 
      University of Medical Sciences, Tehran, Iran.
FAU - Dehghani Firouzabadi, Fatemeh
AU  - Dehghani Firouzabadi F
AD  - ENT and Head and Neck Research Center, The Five Senses Health Institute, Iran 
      University of Medical Sciences, Tehran, Iran.
FAU - Delbandi, Ali-Akbar
AU  - Delbandi AA
AD  - Immunology Research Center, Immunology and Infectious Disease Institute, Iran 
      University of Medical Sciences, Tehran, Iran.
AD  - Department of Immunology, School of Medicine, Iran University of Medical 
      Sciences, Tehran, Iran.
FAU - Ghalehbaghi, Babak
AU  - Ghalehbaghi B
AD  - ENT and Head and Neck Research Center, The Five Senses Health Institute, Iran 
      University of Medical Sciences, Tehran, Iran.
FAU - Daneshi, Ahmad
AU  - Daneshi A
AD  - ENT and Head and Neck Research Center, The Five Senses Health Institute, Iran 
      University of Medical Sciences, Tehran, Iran.
FAU - Yazdani, Nasrin
AU  - Yazdani N
AD  - Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Amir 
      Alam Hospital, Tehran, Iran.
FAU - Fazeli Delshad, Banafsheh
AU  - Fazeli Delshad B
AD  - Immunology Research Center, Immunology and Infectious Disease Institute, Iran 
      University of Medical Sciences, Tehran, Iran.
FAU - Asghari, Alimohamad
AU  - Asghari A
AD  - Skull Base Research Center, The Five Senses Health Institute, Iran University of 
      Medical Sciences, Tehran, Iran.
LA  - eng
PT  - Journal Article
DEP - 20210108
PL  - England
TA  - Immunol Invest
JT  - Immunological investigations
JID - 8504629
RN  - 0 (Allergens)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Allergens
MH  - *Food Hypersensitivity
MH  - Humans
MH  - Immunoglobulin E
MH  - Iran/epidemiology
MH  - *Meniere Disease
OTO - NOTNLM
OT  - Allergy
OT  - Iran
OT  - food allergen
OT  - immune response
OT  - inhalation allergen
OT  - meniere
EDAT- 2021/01/09 06:00
MHDA- 2022/04/06 06:00
CRDT- 2021/01/08 08:36
PHST- 2021/01/09 06:00 [pubmed]
PHST- 2022/04/06 06:00 [medline]
PHST- 2021/01/08 08:36 [entrez]
AID - 10.1080/08820139.2020.1869252 [doi]
PST - ppublish
SO  - Immunol Invest. 2022 Apr;51(3):705-714. doi: 10.1080/08820139.2020.1869252. Epub 
      2021 Jan 8.