PMID- 33416196
OWN - NLM
STAT- MEDLINE
DCOM- 20210514
LR  - 20220803
IS  - 1540-8191 (Electronic)
IS  - 0886-0440 (Linking)
VI  - 36
IP  - 3
DP  - 2021 Mar
TI  - Long-term renal function after venoarterial extracorporeal membrane oxygenation.
PG  - 815-820
LID - 10.1111/jocs.15277 [doi]
AB  - BACKGROUND: The utilization of venoarterial extracorporeal membrane oxygenation 
      (VA-ECMO) as a life-supporting therapy has increased exponentially over the last 
      decade. As more patients receive and survive ECMO, there are a number of 
      unanswered clinical questions about their long-term prognosis and organ function 
      including the need for long-term dialysis. METHODS: We aimed to utilize over 208 
      patient-years of follow-up data from our large institutional cohort of VA-ECMO 
      patients to determine the incidence of requiring VA-ECMO support on the need for 
      renal replacement therapy after discharge (LT-dialysis). This retrospective 
      review included all adult VA-ECMO patients at our institution from January 2014 
      to October 2018 (N = 283). RESULTS: Out of the 99 (35%) survivors, 88 (89%) did 
      not require LT-dialysis of any duration after discharge from the index 
      hospitalization. Patients who required VA-ECMO for decompensated cardiogenic 
      shock were more likely to need LT-dialysis (p = .034), and those who required 
      renal replacement therapy during VA-ECMO (N = 27) also had a higher incidence of 
      LT-dialysis (33%). CONCLUSION: Overall, these data suggest there is a low 
      incidence of long-term dialysis dependence among survivors of VA-ECMO support. 
      Worries about the potential long-term detrimental effect of VA-ECMO should not 
      preclude patients from receiving this life-saving support.
CI  - (c) 2021 Wiley Periodicals LLC.
FAU - Ayers, Brian
AU  - Ayers B
AUID- ORCID: 0000-0003-3667-6873
AD  - Division of Cardiac Surgery, University of Rochester Medical Center, Rochester, 
      New York, USA.
FAU - Bjelic, Milica
AU  - Bjelic M
AUID- ORCID: 0000-0003-0468-8511
AD  - Division of Cardiac Surgery, University of Rochester Medical Center, Rochester, 
      New York, USA.
FAU - Kumar, Neil
AU  - Kumar N
AD  - Division of Cardiac Surgery, University of Rochester Medical Center, Rochester, 
      New York, USA.
FAU - Wood, Katherine
AU  - Wood K
AD  - Division of Cardiac Surgery, University of Rochester Medical Center, Rochester, 
      New York, USA.
FAU - Barrus, Bryan
AU  - Barrus B
AD  - Division of Cardiac Surgery, University of Rochester Medical Center, Rochester, 
      New York, USA.
FAU - Prasad, Sunil
AU  - Prasad S
AD  - Division of Cardiac Surgery, University of Rochester Medical Center, Rochester, 
      New York, USA.
FAU - Gosev, Igor
AU  - Gosev I
AD  - Division of Cardiac Surgery, University of Rochester Medical Center, Rochester, 
      New York, USA.
LA  - eng
GR  - Extracorporeal Life Support Organization/
PT  - Journal Article
DEP - 20210108
PL  - United States
TA  - J Card Surg
JT  - Journal of cardiac surgery
JID - 8908809
SB  - IM
CIN - J Card Surg. 2022 Aug;37(8):2493. PMID: 35441725
CIN - J Card Surg. 2022 Sep;37(9):2934. PMID: 35726655
MH  - Adult
MH  - Cohort Studies
MH  - *Extracorporeal Membrane Oxygenation/adverse effects
MH  - Humans
MH  - Renal Dialysis
MH  - Retrospective Studies
MH  - Shock, Cardiogenic/etiology/therapy
OTO - NOTNLM
OT  - ECMO
OT  - VA-ECMO
OT  - dialysis
OT  - kidney function
OT  - long-term outcomes
EDAT- 2021/01/09 06:00
MHDA- 2021/05/15 06:00
CRDT- 2021/01/08 08:37
PHST- 2020/10/24 00:00 [received]
PHST- 2020/12/06 00:00 [revised]
PHST- 2020/12/15 00:00 [accepted]
PHST- 2021/01/09 06:00 [pubmed]
PHST- 2021/05/15 06:00 [medline]
PHST- 2021/01/08 08:37 [entrez]
AID - 10.1111/jocs.15277 [doi]
PST - ppublish
SO  - J Card Surg. 2021 Mar;36(3):815-820. doi: 10.1111/jocs.15277. Epub 2021 Jan 8.