PMID- 33424508
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210112
IS  - 1551-6776 (Print)
IS  - 2331-348X (Electronic)
IS  - 1551-6776 (Linking)
VI  - 26
IP  - 1
DP  - 2021
TI  - A Distinctive Approach to Venous Thromboembolism Treatment in a Pediatric, 
      Hemodialysis Patient: A Case Report.
PG  - 104-106
LID - 10.5863/1551-6776-26.1.104 [doi]
AB  - Enoxaparin is a low molecular weight heparin (LMWH) that is the mainstay for 
      treatment of pediatric patients with a venous thromboembolism, which provides 
      better compliance compared with the use of unfractionated heparin (UFH) in 
      long-term anticoagulation. Although data are limited in pediatric patients with 
      renal insufficiency, enoxaparin can be used in this population. Data related to 
      its use in hemodialysis (HD) pediatric patients is almost non-existent. A major 
      concern for enoxaparin use in patients with renal insufficiency or for those on 
      HD is bleeding. A few studies in adults showed an increased risk of bleeding, but 
      the risk was similar to that of UFH when the two were compared. This case report 
      describes the use of enoxaparin in an 8-year-old female who is on hemodialysis, 
      without any bleeding or clotting complications. Although systematic trials are 
      needed to support the safety and efficacy of LMWH in pediatric patients with 
      renal dysfunction or on HD, this case will provide limited information for 
      enoxaparin use in this population.
CI  - Copyright Pediatric Pharmacy Association. All rights reserved. For permissions, 
      email: mhelms@pediatricpharmacy.org 2021.
FAU - Koury, Jason
AU  - Koury J
FAU - Schnakenberg, Cintia
AU  - Schnakenberg C
FAU - Villasenor, Charlotte
AU  - Villasenor C
FAU - Abraham, Shirley
AU  - Abraham S
LA  - eng
PT  - Case Reports
DEP - 20210104
PL  - United States
TA  - J Pediatr Pharmacol Ther
JT  - The journal of pediatric pharmacology and therapeutics : JPPT : the official 
      journal of PPAG
JID - 101089851
PMC - PMC7792142
OTO - NOTNLM
OT  - Enoxaparin
OT  - pediatric
OT  - renal dialysis
OT  - venous thromboembolism
COIS- Disclosure. The authors declare no conflicts or financial interest in any product 
      or service mentioned in the manuscript, including grants, equipment, medications, 
      employment, gifts, and honoraria. The authors had full access to all patient 
      information in this report and take responsibility for the integrity and accuracy 
      of the report.
EDAT- 2021/01/12 06:00
MHDA- 2021/01/12 06:01
PMCR- 2021/01/01
CRDT- 2021/01/11 05:35
PHST- 2020/06/10 00:00 [accepted]
PHST- 2021/01/11 05:35 [entrez]
PHST- 2021/01/12 06:00 [pubmed]
PHST- 2021/01/12 06:01 [medline]
PHST- 2021/01/01 00:00 [pmc-release]
AID - 10.5863/1551-6776-26.1.104 [doi]
PST - ppublish
SO  - J Pediatr Pharmacol Ther. 2021;26(1):104-106. doi: 10.5863/1551-6776-26.1.104. 
      Epub 2021 Jan 4.