PMID- 33429645
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210112
IS  - 2373-9878 (Electronic)
IS  - 2373-9878 (Linking)
VI  - 3
IP  - 8
DP  - 2017 Aug 14
TI  - Controlled Hydrophobic Biosurface of Bacterial Cellulose Nanofibers through 
      Self-Assembly of Natural Zein Protein.
PG  - 1595-1604
LID - 10.1021/acsbiomaterials.7b00116 [doi]
AB  - A novel, highly biocompatible bacterial cellulose (BC)-zein composite nanofiber 
      with a controlled hydrophobic biosurface was successfully developed through a 
      simple and green solution impregnation method, followed by evaporation-induced 
      self-assembly (EISA) of adsorbed zein protein. The surface hydrophobicity of the 
      zein-modified BC nanofibers could be controlled by simply changing the zein 
      concentration, which is able to tune the morphology of self-assembled zein 
      structures after EISA, thus affecting the surface roughness of composite 
      membranes. Zein self-assembly at low concentrations (5 mg/mL) resulted in the 
      formation of hierarchical zein structures (spheres and bicontinuous sponges) on 
      the BC surface, thus increasing the surface roughness and leading to high 
      hydrophobicity (the water contact angle reached 110.5 degrees ). However, at high zein 
      concentrations, these large zein spheres assembled into a flat zein film, which 
      decreased the surface roughness and hydrophobicity of membranes. The homogeneous 
      incorporation of zein structures on the BC surface by hydrogen bonding did not 
      significantly change the internal structure and mechanical performance of BC 
      nanofibers. In comparison with pure BC, the BC-zein nanofibers had a better 
      biocompatibility, showing a significantly increased adhesion and proliferation of 
      fibroblast cells. This is probably due to the rough surface structure of BC-zein 
      nanofibers as well as the high biocompatibility of natural zein protein. The 
      novel BC-zein composite nanofibers with controlled surface roughness and 
      hydrophobicity could be of particular interest for the design of BC-based 
      biomaterials and biodevices that require specific surface properties and 
      adhesion.
FAU - Wan, Zhili
AU  - Wan Z
AD  - Research and Development Center of Food Proteins, Department of Food Science and 
      Technology, South China University of Technology, 381 Wushan Road, Tianhe 
      District, Guangzhou 510640, People's Republic of China.
FAU - Wang, Liying
AU  - Wang L
AD  - Research and Development Center of Food Proteins, Department of Food Science and 
      Technology, South China University of Technology, 381 Wushan Road, Tianhe 
      District, Guangzhou 510640, People's Republic of China.
FAU - Ma, Lulu
AU  - Ma L
AD  - Research and Development Center of Food Proteins, Department of Food Science and 
      Technology, South China University of Technology, 381 Wushan Road, Tianhe 
      District, Guangzhou 510640, People's Republic of China.
FAU - Sun, Yingen
AU  - Sun Y
AD  - Research and Development Center of Food Proteins, Department of Food Science and 
      Technology, South China University of Technology, 381 Wushan Road, Tianhe 
      District, Guangzhou 510640, People's Republic of China.
FAU - Yang, Xiaoquan
AU  - Yang X
AUID- ORCID: 0000-0002-4016-9834
AD  - Research and Development Center of Food Proteins, Department of Food Science and 
      Technology, South China University of Technology, 381 Wushan Road, Tianhe 
      District, Guangzhou 510640, People's Republic of China.
AD  - Guangdong Province Key Laboratory for Green Processing of Natural Products and 
      Product Safety, South China University of Technology, 381 Wushan Road, Tianhe 
      District, Guangzhou 510640, People's Republic of China.
LA  - eng
PT  - Journal Article
DEP - 20170621
PL  - United States
TA  - ACS Biomater Sci Eng
JT  - ACS biomaterials science & engineering
JID - 101654670
SB  - IM
OTO - NOTNLM
OT  - bacterial cellulose nanofibers
OT  - cell adhesion
OT  - controlled self-assembly
OT  - hydrophobic biointerface
OT  - surface modification
OT  - zein
EDAT- 2017/08/14 00:00
MHDA- 2017/08/14 00:01
CRDT- 2021/01/12 01:00
PHST- 2021/01/12 01:00 [entrez]
PHST- 2017/08/14 00:00 [pubmed]
PHST- 2017/08/14 00:01 [medline]
AID - 10.1021/acsbiomaterials.7b00116 [doi]
PST - ppublish
SO  - ACS Biomater Sci Eng. 2017 Aug 14;3(8):1595-1604. doi: 
      10.1021/acsbiomaterials.7b00116. Epub 2017 Jun 21.