PMID- 33431910
OWN - NLM
STAT- MEDLINE
DCOM- 20210805
LR  - 20210805
IS  - 2045-2322 (Electronic)
IS  - 2045-2322 (Linking)
VI  - 11
IP  - 1
DP  - 2021 Jan 11
TI  - Impacts of monocular, binocular, and functional visual acuity on vision-related 
      quality of life in patients with type 2 diabetes.
PG  - 298
LID - 10.1038/s41598-020-79483-9 [doi]
LID - 298
AB  - Although the association between visual acuity (VA) and vision-related quality of 
      life (VRQoL) has been well reported in patients with type 2 diabetes mellitus 
      (T2DM), little is known about how unilateral and bilateral VA affects daily 
      performance in such patients. For this cross-sectional study, patients were 
      recruited from the Diabetes Shared Care Network of the Division of Endocrinology 
      and Metabolism, Zhong-Xiao Branch, Taipei City Hospital in Taiwan. Ninety 
      patients with T2DM (51 men and 39 women) with a mean age of 60.3 +/- 10.5 (standard 
      deviation) years, 47% of whom had diabetic retinopathy, were included. The 
      purposes were to compare the impacts of VA in the better eye, both eyes, and 
      three forms of functional acuity scores (FAS) on VRQoL in patients with T2DM. 
      VRQoL and corrected VA were assessed with the 25-item National Eye Institute 
      Visual Function Questionnaire (NEI VFQ-25) and Early Treatment Diabetic 
      Retinopathy Study (ETDRS) chart, respectively. Three FAS algorithms proposed by 
      Colenbrander and the American Medical Association were used to assess FAS. 
      Regression analyses were performed to determine the correlations among the five 
      types of VA, the original composite scores, and the Rasch-calibrated composite 
      scores of the NEI VFQ-25 on all patients with T2DM and on the same patients 
      stratified by diabetic retinopathy (DR) and no-DR. The VA of both eyes had a 
      higher impact on VRQoL and revealed a lower reduction estimated by the two forms 
      of composite scores than did the VA of the better eye and three FAS algorithms 
      (compared with binocular VA beta estimates, - 14.5%, - 15.8%, - 29.3%, and - 11.8% 
      for original composite scores, and - 16.1%, - 14.0%, - 24.6%, and 10.3% for 
      Rasch-calibrated composite scores). When the T2DM group was stratified into DR 
      and no-DR groups, significant associations between VA and VRQoL were observed 
      only in the DR group. The VA of both eyes also had the greatest impact and 
      reduction after stratification. The results indicated that unilateral better-eye 
      VA and VA estimated by the three FAS algorithms seems to underestimate the impact 
      of visual impairment on self-report VRQoL in patients with T2DM. This study 
      provides empirical support for the importance of binocular VA assessment in 
      regular clinical diabetes eye care.
FAU - Liao, Kuo-Meng
AU  - Liao KM
AD  - Division of Endocrinology and Metabolism, Department of Internal Medicine, 
      Zhong-Xiao Branch, Taipei City Hospital, Taipei, Taiwan.
FAU - Wu, Wei-Chi
AU  - Wu WC
AD  - Department of Ophthalmology, Chang Gung Memorial Hospital and Chang Gung 
      University, School of Medicine, Taoyuan, Taiwan.
FAU - Jang, Yuh
AU  - Jang Y
AD  - School of Occupational Therapy, College of Medicine, National Taiwan University, 
      4F, No. 17, Xuzhou Rd., Zhongzheng Dist., Taipei, 100, Taiwan.
FAU - Su, Fan-Ya
AU  - Su FY
AD  - Department of Psychiatry, Taipei Medical University-Shuang Ho Hospital, New 
      Taipei City, Taiwan.
FAU - Tsai, Li-Ting
AU  - Tsai LT
AD  - School of Occupational Therapy, College of Medicine, National Taiwan University, 
      4F, No. 17, Xuzhou Rd., Zhongzheng Dist., Taipei, 100, Taiwan. 
      tingwind718@gmail.com.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20210111
PL  - England
TA  - Sci Rep
JT  - Scientific reports
JID - 101563288
SB  - IM
MH  - Adult
MH  - Aged
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus, Type 2/*physiopathology
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Quality of Life
MH  - Surveys and Questionnaires
MH  - *Vision, Binocular
MH  - *Visual Acuity
PMC - PMC7801718
COIS- The authors declare no competing interests.
EDAT- 2021/01/13 06:00
MHDA- 2021/08/06 06:00
PMCR- 2021/01/11
CRDT- 2021/01/12 06:03
PHST- 2020/09/05 00:00 [received]
PHST- 2020/12/09 00:00 [accepted]
PHST- 2021/01/12 06:03 [entrez]
PHST- 2021/01/13 06:00 [pubmed]
PHST- 2021/08/06 06:00 [medline]
PHST- 2021/01/11 00:00 [pmc-release]
AID - 10.1038/s41598-020-79483-9 [pii]
AID - 79483 [pii]
AID - 10.1038/s41598-020-79483-9 [doi]
PST - epublish
SO  - Sci Rep. 2021 Jan 11;11(1):298. doi: 10.1038/s41598-020-79483-9.