PMID- 33433840 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20210320 IS - 1935-973X (Print) IS - 1935-9748 (Electronic) IS - 1935-9748 (Linking) VI - 14 IP - 1 DP - 2021 Feb TI - Minimal Clinically Important Difference, Substantial Clinical Benefit, and Patient Acceptable Symptom State of Outcome Measures Relating to Shoulder Pathology and Surgery: a Systematic Review. PG - 27-46 LID - 10.1007/s12178-020-09684-2 [doi] AB - PURPOSE OF THE REVIEW: To provide a comprehensive summary of available literature on the minimal clinically important difference (MCID), substantial clinical benefit (SCB), and patient acceptable symptom state (PASS) of patient-reported outcome measures (PROMs) for various shoulder conditions and outcomes and to identify factors that influence these metrics. RECENT FINDINGS: Over the past 2 years, there has been an increasing interest in utilizing MCID, SCB, and PASS as a gauge to evaluate the success of an intervention for shoulder conditions. Efforts at calculating these thresholds have yielded multiple and inconsistent values and are further compounded by the proliferation of different PROMs in the shoulder literature. The MCID, SCB, and PASS values of shoulder PROMs vary widely with study-specific characteristics, including patient demographics, shoulder pathology, treatment, shoulder instrument, study methodology, and calculation method. The differences in these factors are not inconsequential and could lead to large discrepancies in threshold values. It is crucial that clinicians are mindful of these variables when designing future studies to calculate these metrics or when utilizing previously published values to determine the success of an intervention. FAU - Su, Favian AU - Su F AUID- ORCID: 0000-0002-1170-0665 AD - Department of Orthopaedic Surgery, University of California, San Francisco, San Francisco, CA, USA. FAU - Allahabadi, Sachin AU - Allahabadi S AUID- ORCID: 0000-0002-1185-3039 AD - Department of Orthopaedic Surgery, University of California, San Francisco, San Francisco, CA, USA. FAU - Bongbong, Dale N AU - Bongbong DN AD - School of Medicine, University of California, San Diego, San Diego, CA, USA. FAU - Feeley, Brian T AU - Feeley BT AUID- ORCID: 0000-0002-4215-9664 AD - Department of Orthopaedic Surgery, University of California, San Francisco, San Francisco, CA, USA. FAU - Lansdown, Drew A AU - Lansdown DA AUID- ORCID: 0000-0001-8086-6776 AD - Department of Orthopaedic Surgery, University of California, San Francisco, San Francisco, CA, USA. Drew.Lansdown@ucsf.edu. LA - eng PT - Journal Article PT - Review DEP - 20210112 PL - United States TA - Curr Rev Musculoskelet Med JT - Current reviews in musculoskeletal medicine JID - 101317803 PMC - PMC7930136 OTO - NOTNLM OT - Minimal clinical important difference OT - Outcomes OT - Patient acceptable symptom state OT - Shoulder OT - Substantial clinical benefit COIS- Favian Su, Sachin Allahabadi, and Dale Bongbong declare that they have no conflict of interest. Brian T Feeley has the following disclosures: Consultant for Kaliber, Inc.; hospitality and educational payments from Zimmer Biomet, Inc.; American Orthopedic Society for Sports Medicine: Board or committee member; Current Reviews in Musculoskeletal Medicine: Editorial or governing board; Journal of Shoulder and Elbow Surgery: Editorial or governing board; Orthopedic Research Society: Board or committee member. Drew A Lansdown has the following disclosures: Received fellowship-related research/education funding from Arthrex, Inc. and Smith & Nephew; educational support from Medwest; hospitality payments from Wright Medical; Arthroscopy Association of North America: Board or committee member, American Orthopedic Society for Sports Medicine: Board or committee member. EDAT- 2021/01/13 06:00 MHDA- 2021/01/13 06:01 PMCR- 2021/01/12 CRDT- 2021/01/12 12:24 PHST- 2020/12/17 00:00 [accepted] PHST- 2021/01/13 06:00 [pubmed] PHST- 2021/01/13 06:01 [medline] PHST- 2021/01/12 12:24 [entrez] PHST- 2021/01/12 00:00 [pmc-release] AID - 10.1007/s12178-020-09684-2 [pii] AID - 9684 [pii] AID - 10.1007/s12178-020-09684-2 [doi] PST - ppublish SO - Curr Rev Musculoskelet Med. 2021 Feb;14(1):27-46. doi: 10.1007/s12178-020-09684-2. Epub 2021 Jan 12.