PMID- 33439453 OWN - NLM STAT- MEDLINE DCOM- 20210929 LR - 20210929 IS - 1741-0444 (Electronic) IS - 0140-0118 (Linking) VI - 59 IP - 2 DP - 2021 Feb TI - An enhanced deep image model for glaucoma diagnosis using feature-based detection in retinal fundus. PG - 333-353 LID - 10.1007/s11517-020-02307-5 [doi] AB - This paper proposes a deep image analysis-based model for glaucoma diagnosis that uses several features to detect the formation of glaucoma in retinal fundus. These features are combined with most extracted parameters like inferior, superior, nasal, and temporal region area, and cup-to-disc ratio that overall forms a deep image analysis. This proposed model is exercised to investigate the various aspects related to the prediction of glaucoma in retinal fundus images that help the ophthalmologist in making better decisions for the human eye. The proposed model is presented with the combination of four machine learning algorithms that provide the classification accuracy of 98.60% while other existing models like support vector machine (SVM), K-nearest neighbors (KNN), and Naive Bayes provide individually with accuracies of 97.61%, 90.47%, and 95.23% respectively. These results clearly demonstrate that this proposed model offers the best methodology to an early diagnosis of glaucoma in retinal fundus. FAU - Singh, Law Kumar AU - Singh LK AD - Department of Computer Science and Engineering, School of Engineering and Technology, Sharda University, Knowledge Park III, Greater Noida, India. AD - Department of Computer Science and Engineering, Hindustan College of Science and Technology, Mathura, India. FAU - Pooja AU - Pooja AD - Department of Computer Science and Engineering, School of Engineering and Technology, Sharda University, Knowledge Park III, Greater Noida, India. FAU - Garg, Hitendra AU - Garg H AD - Department of Computer Engineering and Applications, GLA University, Mathura, India. FAU - Khanna, Munish AU - Khanna M AD - Department of Computer Science and Engineering, Hindustan College of Science and Technology, Mathura, India. FAU - Bhadoria, Robin Singh AU - Bhadoria RS AUID- ORCID: 0000-0002-6314-4736 AD - Department of Computer Science and Engineering, Birla Institute of Applied Sciences (BIAS), Bhimtal, Uttarakhand, India. robin19@ieee.org. LA - eng PT - Journal Article DEP - 20210113 PL - United States TA - Med Biol Eng Comput JT - Medical & biological engineering & computing JID - 7704869 SB - IM MH - Algorithms MH - Bayes Theorem MH - Fundus Oculi MH - *Glaucoma/diagnosis MH - Humans MH - Image Interpretation, Computer-Assisted OTO - NOTNLM OT - Cup-to-disc ratio OT - Glaucoma diagnosis OT - Inferior superior nasal temporal (ISNT) regions OT - Machine learning OT - Retinal fundus image EDAT- 2021/01/14 06:00 MHDA- 2021/09/30 06:00 CRDT- 2021/01/13 12:14 PHST- 2020/05/25 00:00 [received] PHST- 2020/12/26 00:00 [accepted] PHST- 2021/01/14 06:00 [pubmed] PHST- 2021/09/30 06:00 [medline] PHST- 2021/01/13 12:14 [entrez] AID - 10.1007/s11517-020-02307-5 [pii] AID - 10.1007/s11517-020-02307-5 [doi] PST - ppublish SO - Med Biol Eng Comput. 2021 Feb;59(2):333-353. doi: 10.1007/s11517-020-02307-5. Epub 2021 Jan 13.