PMID- 33442083
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220419
IS  - 0857-1074 (Print)
IS  - 2308-118X (Electronic)
IS  - 0857-1074 (Linking)
VI  - 32
IP  - 1
DP  - 2017
TI  - Efficacy of Magnesium Supplementation on Glycemic Control in Type 2 Diabetes 
      Patients: A Meta-analysis.
PG  - 38-45
LID - 10.15605/jafes.032.01.07 [doi]
AB  - OBJECTIVE: To evaluate if magnesium supplementation, in addition to standard 
      therapy, improves fasting blood sugar (FBS) and/or glycosylated hemoglobin 
      (HbA1c) in patients with type 2 diabetes mellitus (T2DM) compared to placebo or 
      other comparator. METHODOLOGY: We searched MEDLINE/PubMed, Cochrane Library, Acta 
      Medica Philippina, Health Research and Development Information Network (HERDIN) 
      and references of reviewed journals from 1966 to July 2015 using the following 
      search terms: "magnesium" OR "magnesium supplementation" OR "magnesium 
      replacement", AND randomized controlled trial AND diabetes OR diabetes mellitus 
      OR non-insulin dependent diabetes mellitus OR diabetic OR diab* (with MeSH, where 
      available). Studies were retrieved and rated independently using the standards 
      provided by The Cochrane Collaboration. High quality trials were included in a 
      systematic review and meta-analysis. RESULTS: Of the 689 records screened, 10 
      studies were included in the qualitative synthesis and 7 studies in the 
      meta-analysis. Pooled data showed a non-significant trend towards improvement in 
      glycemic control in the magnesium-treated group (mean difference -0.19, CI -0.58 
      to 0.21). There was a stronger but still non-significant trend in T2DM patients 
      with hypomagnesemia (mean difference -1.16, CI -2.92 to 0.6). CONCLUSION: Routine 
      magnesium supplementation for improvement in glycemic control in T2DM patients 
      cannot be recommended based on data from included studies in this meta-analysis.
CI  - (c) 2017 Journal of the ASEAN Federation of Endocrine Societies.
FAU - Chua, Francis Bryant
AU  - Chua FB
AD  - Section of Endocrinology and Metabolism, Department of Medicine, The Medical 
      City, Pasig City, Philippines.
FAU - Cinco, Jude Erric
AU  - Cinco JE
AD  - Section of Cardiology, Department of Medicine, The Medical City, Pasig City, 
      Philippines.
FAU - Paz-Pacheco, Elizabeth
AU  - Paz-Pacheco E
AD  - Section of Endocrinology and Metabolism, Department of Medicine, The Medical 
      City, Pasig City, Philippines.
LA  - eng
PT  - Journal Article
DEP - 20170505
PL  - Philippines
TA  - J ASEAN Fed Endocr Soc
JT  - Journal of the ASEAN Federation of Endocrine Societies
JID - 8608483
PMC - PMC7784187
OTO - NOTNLM
OT  - diabetes
OT  - glycemic control
OT  - magnesium
OT  - meta-analysis
OT  - supplementation
COIS- The authors have declared no conflict of interest.
EDAT- 2017/01/01 00:00
MHDA- 2017/01/01 00:01
PMCR- 2017/01/01
CRDT- 2021/01/14 05:46
PHST- 2016/05/04 00:00 [received]
PHST- 2016/07/13 00:00 [accepted]
PHST- 2021/01/14 05:46 [entrez]
PHST- 2017/01/01 00:00 [pubmed]
PHST- 2017/01/01 00:01 [medline]
PHST- 2017/01/01 00:00 [pmc-release]
AID - JAFES-32-1-038 [pii]
AID - 10.15605/jafes.032.01.07 [doi]
PST - ppublish
SO  - J ASEAN Fed Endocr Soc. 2017;32(1):38-45. doi: 10.15605/jafes.032.01.07. Epub 
      2017 May 5.