PMID- 33442091
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210115
IS  - 0857-1074 (Print)
IS  - 2308-118X (Electronic)
IS  - 0857-1074 (Linking)
VI  - 32
IP  - 2
DP  - 2017
TI  - Bone Metabolism and Fracture Risk in Diabetes Mellitus.
PG  - 90-99
LID - 10.15605/jafes.032.02.14 [doi]
AB  - Individuals with Type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus 
      (T2DM) are at increased risk for fragility fractures. Bone mineral density (BMD) 
      is decreased in T1DM but often normal or even elevated in T2DM when compared with 
      age-matched non-DM populations. However, bone turnover is decreased in both T1DM 
      and T2DM. The pathophysiologic mechanisms leading to bone fragility is 
      multifactorial, and potentially leads to reduced bone formation, altered bone 
      microstructure and decreased bone strength. Interestingly, different antidiabetic 
      treatments may influence fracture risk due to effects on glycemic control, 
      triggering of hypoglycemic events or osteoblastogenesis.
CI  - (c) 2017 Journal of the ASEAN Federation of Endocrine Societies.
FAU - Puspitasari, Melisa
AU  - Puspitasari M
AD  - Department of Internal Medicine, Faculty of Medicine University of Indonesia, 
      Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
FAU - Purnamasari, Dyah
AU  - Purnamasari D
AD  - Division of Metabolism and Endocrinology, Department of Internal Medicine, 
      Faculty of Medicine University of Indonesia, Cipto Mangunkusumo Hospital, 
      Jakarta, Indonesia.
FAU - Setyohadi, Bambang
AU  - Setyohadi B
AD  - Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine 
      University of Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
FAU - Isbagio, Harry
AU  - Isbagio H
AD  - Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine 
      University of Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20171015
PL  - Philippines
TA  - J ASEAN Fed Endocr Soc
JT  - Journal of the ASEAN Federation of Endocrine Societies
JID - 8608483
PMC - PMC7784240
OTO - NOTNLM
OT  - biomarkers
OT  - bone metabolism
OT  - bone remodeling
OT  - diabetes mellitus
COIS- The authors declared no conflict of interest.
EDAT- 2017/01/01 00:00
MHDA- 2017/01/01 00:01
PMCR- 2017/01/01
CRDT- 2021/01/14 05:46
PHST- 2017/08/28 00:00 [received]
PHST- 2017/09/30 00:00 [accepted]
PHST- 2021/01/14 05:46 [entrez]
PHST- 2017/01/01 00:00 [pubmed]
PHST- 2017/01/01 00:01 [medline]
PHST- 2017/01/01 00:00 [pmc-release]
AID - JAFES-32-2-090 [pii]
AID - 10.15605/jafes.032.02.14 [doi]
PST - ppublish
SO  - J ASEAN Fed Endocr Soc. 2017;32(2):90-99. doi: 10.15605/jafes.032.02.14. Epub 
      2017 Oct 15.