PMID- 33448636 OWN - NLM STAT- MEDLINE DCOM- 20220124 LR - 20220124 IS - 1520-7560 (Electronic) IS - 1520-7552 (Linking) VI - 37 IP - 3 DP - 2021 Mar TI - A systematic review of factors associated with uncontrolled diabetes and meta-analysis of its prevalence in Saudi Arabia since 2006. PG - e3395 LID - 10.1002/dmrr.3395 [doi] AB - The study aims to systematically review the literature for risk factors associated with poor glycaemic control among type 2 diabetes mellitus (T2DM) patients in Saudi Arabia (SA) and conducts a meta-analysis of its prevalence. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol, we searched the Scopus, PubMed, PsycINFO, Web of Science, and CINAHL Plus databases from May to November 2018. The search terms were T2DM, glycaemic control, and SA. The inclusion criteria include the following: observational studies which were conducted in T2DM patients in SA reporting prevalence or/and personal, psychological or behavioural predictors in papers published after 2006. Articles were assessed using a modified Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) tool. Studies included in the meta-analysis defined uncontrolled T2DM as glycated haemoglobin >/=7% (53 mmol/mol), and reported results were based on a random-effects model. Eighteen of the following articles (3 retrospective cohort studies, 1 case-control study, and 14 cross-sectional studies) were included. The quality of the studies (high: 2; moderate: 7, and low: 9) varied. The pooled prevalence of uncontrolled T2DM in SA was 77.7% (95% CI, 71.2-84.2). In the included studies, the most consistent predictors of poor glycaemic control were longer diabetes duration, lack of self-efficacy, and low knowledge of diabetes. However, significant variations in research designs were observed across the studies. A national diabetes prevention and treatment program is needed to lessen the burden of diabetes in SA. Future studies should address the personal, psychological, and behavioural factors of poor glycaemic control in SA at national level. CI - (c) 2020 John Wiley & Sons Ltd. FAU - Alsuliman, Mohammed A AU - Alsuliman MA AUID- ORCID: 0000-0002-9466-2624 AD - School of Community and Environmental Health, Old Dominion University, Norfolk, Virginia, USA. AD - Department of Public Health, College of Health Sciences, Saudi Electronic University, Riyadh, Saudi Arabia. FAU - Alotaibi, Saad A AU - Alotaibi SA AD - School of Community and Environmental Health, Old Dominion University, Norfolk, Virginia, USA. AD - Department of Human Health, College of Applied Medical Sciences, Qassim University, Qassim, Saudi Arabia. FAU - Zhang, Qi AU - Zhang Q AD - School of Community and Environmental Health, Old Dominion University, Norfolk, Virginia, USA. FAU - Durgampudi, Praveen K AU - Durgampudi PK AD - School of Community and Environmental Health, Old Dominion University, Norfolk, Virginia, USA. LA - eng PT - Journal Article PT - Meta-Analysis PT - Systematic Review DEP - 20200908 PL - England TA - Diabetes Metab Res Rev JT - Diabetes/metabolism research and reviews JID - 100883450 SB - IM MH - *Diabetes Mellitus, Type 2/epidemiology MH - Humans MH - *Hyperglycemia/epidemiology MH - Prevalence MH - Risk Factors MH - Saudi Arabia/epidemiology OTO - NOTNLM OT - HbA1c OT - Saudi Arabia OT - T2DM OT - meta-analysis OT - prevalence OT - risk factors EDAT- 2021/01/16 06:00 MHDA- 2022/01/27 06:00 CRDT- 2021/01/15 08:47 PHST- 2020/07/18 00:00 [revised] PHST- 2019/05/17 00:00 [received] PHST- 2020/08/13 00:00 [accepted] PHST- 2021/01/16 06:00 [pubmed] PHST- 2022/01/27 06:00 [medline] PHST- 2021/01/15 08:47 [entrez] AID - 10.1002/dmrr.3395 [doi] PST - ppublish SO - Diabetes Metab Res Rev. 2021 Mar;37(3):e3395. doi: 10.1002/dmrr.3395. Epub 2020 Sep 8.