PMID- 33450409 OWN - NLM STAT- MEDLINE DCOM- 20210819 LR - 20210819 IS - 1526-3231 (Electronic) IS - 0749-8063 (Linking) VI - 37 IP - 6 DP - 2021 Jun TI - Establishing Clinically Significant Outcomes for Patient-Reported Outcomes Measurement Information System After Biceps Tenodesis. PG - 1731-1739 LID - S0749-8063(21)00010-4 [pii] LID - 10.1016/j.arthro.2020.12.236 [doi] AB - PURPOSE: To establish thresholds for improvement in patient-reported outcome scores that correspond with clinically significant outcomes (CSOs) including the minimal clinically important difference (MCID), substantial clinical benefit (SCB), and patient acceptable symptomatic state (PASS) for Patient-Reported Outcomes Measurement Information System (PROMIS) upper extremity (UE) computer adaptive testing (CAT) and pain interference (PIF) CAT after biceps tenodesis (BT) and to assess patient variables that are associated with achieving these outcomes. METHODS: After institutional review board approval was obtained, a prospectively maintained institutional database was queried for patients undergoing BT between December 2017 and August 2019. Patients undergoing BT in isolation or BT in conjunction with rotator cuff debridement, SLAP repair, subacromial decompression, or distal clavicle excision were included in the analysis. Anchor- and distribution-based methods were used to calculate the MCID whereas an anchor-based method was used to calculate SCB and the PASS for PROMIS UE CAT and PIF CAT. RESULTS: A total of 112 patients (86.8% follow-up) who underwent BT were included for analysis. The MCID, net SCB, absolute SCB, and PASS for PROMIS UE CAT were 4.02, 9.25, 43.4, and 41.1, respectively. The MCID, net SCB, absolute SCB, and PASS for PROMIS PIF CAT were -4.12, -10.7, 52.4, and 52.4, respectively. Higher preoperative UE CAT and PIF CAT scores, preoperative opioid use, depression, and living alone were negative predictors of CSO achievement. Male sex and regular participation in exercise were positive predictors of CSO achievement. CONCLUSIONS: Patients with higher preoperative UE scores were less likely to achieve the MCID (odds ratio [OR], 0.84), whereas patients with higher preoperative PIF scores were less likely to achieve absolute SCB and the PASS (OR, 0.83-0.89). Most patients achieved the MCID for PIF CAT (70.5%) and UE CAT (62.5%) at final follow-up. Male sex (OR, 4.38-9.15) and regular exercise participation (OR, 6.45-18.94) positively predicted CSO achievement, whereas preoperative opioid use (OR, 0.06), depression (OR, 0.23), and living alone (OR, 0.90) were negative predictors of CSO achievement. LEVEL OF EVIDENCE: Level IV, case series. CI - Copyright (c) 2021. Published by Elsevier Inc. FAU - Forlenza, Enrico M AU - Forlenza EM AD - Rush University Medical Center, Chicago, Illinois, U.S.A. FAU - Lu, Yining AU - Lu Y AD - Rush University Medical Center, Chicago, Illinois, U.S.A. FAU - Cohn, Matthew R AU - Cohn MR AD - Rush University Medical Center, Chicago, Illinois, U.S.A. FAU - Baker, James AU - Baker J AD - Rush University Medical Center, Chicago, Illinois, U.S.A. FAU - Lavoie-Gagne, Ophelie AU - Lavoie-Gagne O AD - Rush University Medical Center, Chicago, Illinois, U.S.A. FAU - Yanke, Adam B AU - Yanke AB AD - Rush University Medical Center, Chicago, Illinois, U.S.A. FAU - Cole, Brian J AU - Cole BJ AD - Rush University Medical Center, Chicago, Illinois, U.S.A. FAU - Verma, Nikhil N AU - Verma NN AD - Rush University Medical Center, Chicago, Illinois, U.S.A. FAU - Forsythe, Brian AU - Forsythe B AD - Rush University Medical Center, Chicago, Illinois, U.S.A.. Electronic address: brian.forsythe@rushortho.com. LA - eng PT - Journal Article DEP - 20210113 PL - United States TA - Arthroscopy JT - Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association JID - 8506498 SB - IM MH - Arthroscopy MH - Humans MH - Information Systems MH - Male MH - Minimal Clinically Important Difference MH - Patient Reported Outcome Measures MH - *Tenodesis MH - Treatment Outcome EDAT- 2021/01/16 06:00 MHDA- 2021/08/20 06:00 CRDT- 2021/01/15 20:10 PHST- 2020/06/05 00:00 [received] PHST- 2020/12/28 00:00 [revised] PHST- 2020/12/29 00:00 [accepted] PHST- 2021/01/16 06:00 [pubmed] PHST- 2021/08/20 06:00 [medline] PHST- 2021/01/15 20:10 [entrez] AID - S0749-8063(21)00010-4 [pii] AID - 10.1016/j.arthro.2020.12.236 [doi] PST - ppublish SO - Arthroscopy. 2021 Jun;37(6):1731-1739. doi: 10.1016/j.arthro.2020.12.236. Epub 2021 Jan 13.