PMID- 33453709 OWN - NLM STAT- MEDLINE DCOM- 20211213 LR - 20240402 IS - 1303-6165 (Electronic) IS - 1300-0144 (Print) IS - 1300-0144 (Linking) VI - 51 IP - 3 DP - 2021 Jun 28 TI - Prognostic value of the C-reactive protein to albumin ratio in patients undergoing primary percutaneous coronary intervention for ST-segment elevation myocardial infarction. PG - 1281-1288 LID - 10.3906/sag-2003-188 [doi] AB - BACKGROUND/AIM: This study investigated whether baseline serum level of C-reactive protein (CRP)/albumin ratio is associated with infarct localization, number of vascular lesions, and in-hospital mortality in patients undergoing primary percutaneous coronary intervention (PCI) for acute ST elevation myocardial infarction (STEMI). METHODS: The study population consisted of 116 patients diagnosed with STEMI. The CRP/albumin ratio at first admission, cardiac troponin-I (cTnI), PCI results, and clinical outcomes were recorded. RESULTS: The mean CRP/albumin ratio, cTnI level, and mean number of vascular lesions were significantly higher in non-survivors than in survivors (p = 0.006, p = 0.004, and p = 0.007, respectively). Multivariate logistic regression analysis demonstrated that the CRP/ albumin ratio and number of coronary artery lesions were independent predictors of mortality in STEMI patients. According to these analyses, the presence of >/= 2 vessel lesions was the most important predictor of mortality, with an odds ratio of 2.009 (95% confidence interval: 1.191-3.387, p = 0.009). CONCLUSION: This study demonstrates the potential utility of the CRP/albumin ratio for predicting the clinical outcome of patients with STEMI. In addition, the presence of >/= 2 vascular lesions contributed to a 2-fold increase in mortality rate in STEMI patients. CI - This work is licensed under a Creative Commons Attribution 4.0 International License. FAU - Sogut, Ozgur AU - Sogut O AUID- ORCID: 0000-0003-3365-3713 AD - Department of Emergency Medicine, Haseki Training and Research Hospital, University of Health Sciences, Istanbul, Turkey FAU - Akdemir, Tarik AU - Akdemir T AUID- ORCID: 0000-0003-1178-2274 AD - Department of Emergency Medicine, Haseki Training and Research Hospital, University of Health Sciences, Istanbul, Turkey FAU - Can, Mehmet Mustafa AU - Can MM AUID- ORCID: 0000-0002-7786-5198 AD - Department of Cardiology, Haseki Training and Research Hospital, University of Health Sciences, Istanbul, Turkey LA - eng PT - Journal Article DEP - 20210628 PL - Turkey TA - Turk J Med Sci JT - Turkish journal of medical sciences JID - 9441758 RN - 9007-41-4 (C-Reactive Protein) SB - IM MH - C-Reactive Protein MH - Hospital Mortality MH - Humans MH - *Percutaneous Coronary Intervention MH - Prognosis MH - *ST Elevation Myocardial Infarction/surgery PMC - PMC8283510 OTO - NOTNLM OT - CRP/albumin ratio OT - ST-elevation myocardial infarction OT - infarction localization OT - prognosis OT - vascular lesion number COIS- The authors have no conflicts of interest to declare. No funding support was used to carry out the research. EDAT- 2021/01/18 06:00 MHDA- 2021/12/15 06:00 PMCR- 2021/06/28 CRDT- 2021/01/17 06:40 PHST- 2020/03/22 00:00 [received] PHST- 2021/01/16 00:00 [accepted] PHST- 2021/01/17 06:40 [entrez] PHST- 2021/01/18 06:00 [pubmed] PHST- 2021/12/15 06:00 [medline] PHST- 2021/06/28 00:00 [pmc-release] AID - 10.3906/sag-2003-188 [doi] PST - epublish SO - Turk J Med Sci. 2021 Jun 28;51(3):1281-1288. doi: 10.3906/sag-2003-188.