PMID- 33455544 OWN - NLM STAT- MEDLINE DCOM- 20210713 LR - 20210713 IS - 1944-0057 (Electronic) IS - 1944-0057 (Linking) VI - 38 IP - 3 DP - 2021 Mar TI - Determination and risk assessment of perfluorinated alkylated substances (PFASs) in pork liver from mainland, China. PG - 427-438 LID - 10.1080/19440049.2020.1856941 [doi] AB - Animal-origin food has been suggested as the main dietary source of perfluorinated alkylated substances (PFASs) for humans, and pork liver is a major contributor. The nationwide survey data of PFASs from pork liver in China was limited. This study determined 17 PFASs in pork liver samples from 30 regions including different provinces, autonomous regions and municipalities, using traditional high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). The average detection rate of PFASs (>/=the limit of detection, LOD) in pork liver samples throughout China reached 97.4%, with SigmaPFASs of 1.80 mug/kg. Both in areas with well-developed manufacturing industries and in non-production areas of perfluorinated compounds, PFASs were widely detectable in pork liver samples, especially for perfluorooctanoic acid (PFOA) and perfluorooctane sulphonate (PFOS). The detection rates of PFOA and PFOS (>/=LOD) were 77.0% and 86.1%, with contents of 0.160 mug/kg and 0.397 mug/kg. The risk assessments of PFOA and PFOS from pork liver for different populations demonstrated the necessity for continuous exposure monitoring and risk investigation of PFASs. This work accomplished systematic and nationwide determination data of PFASs in pork liver, and provides a valuable reference for contamination monitoring and risk assessment of PFASs from animal origin food. FAU - Zhang, Juan AU - Zhang J AD - Institute of Quality Standards and Testing Technology for Agro-products, Chinese Academy of Agricultural Sciences, Haidian, Beijing, China. FAU - Qiao, Lu AU - Qiao L AD - Institute of Quality Standards and Testing Technology for Agro-products, Chinese Academy of Agricultural Sciences, Haidian, Beijing, China. FAU - Li, Hui AU - Li H AD - Institute of Quality Standards and Testing Technology for Agro-products, Chinese Academy of Agricultural Sciences, Haidian, Beijing, China. FAU - Yang, Shuming AU - Yang S AD - Institute of Quality Standards and Testing Technology for Agro-products, Chinese Academy of Agricultural Sciences, Haidian, Beijing, China. FAU - Chen, Ailiang AU - Chen A AD - Institute of Quality Standards and Testing Technology for Agro-products, Chinese Academy of Agricultural Sciences, Haidian, Beijing, China. LA - eng PT - Journal Article DEP - 20210116 PL - England TA - Food Addit Contam Part A Chem Anal Control Expo Risk Assess JT - Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment JID - 101485040 RN - 0 (Alkanesulfonic Acids) RN - 0 (Caprylates) RN - 0 (Fluorocarbons) RN - 947VD76D3L (perfluorooctanoic acid) RN - 9H2MAI21CL (perfluorooctane sulfonic acid) SB - IM MH - Alkanesulfonic Acids/analysis MH - Animals MH - Caprylates/analysis MH - China MH - Chromatography, High Pressure Liquid MH - Environmental Monitoring MH - Fluorocarbons/*analysis MH - Food Contamination/*analysis MH - Food Safety MH - Humans MH - Limit of Detection MH - Liver/*chemistry MH - Risk Assessment MH - Swine MH - Tandem Mass Spectrometry OTO - NOTNLM OT - Perfluorinated alkyl substances OT - perfluorooctane sulphonate OT - perfluorooctanoic acid OT - pork liver OT - risk assessment EDAT- 2021/01/19 06:00 MHDA- 2021/07/14 06:00 CRDT- 2021/01/18 05:22 PHST- 2021/01/19 06:00 [pubmed] PHST- 2021/07/14 06:00 [medline] PHST- 2021/01/18 05:22 [entrez] AID - 10.1080/19440049.2020.1856941 [doi] PST - ppublish SO - Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2021 Mar;38(3):427-438. doi: 10.1080/19440049.2020.1856941. Epub 2021 Jan 16.