PMID- 33461649
OWN - NLM
STAT- MEDLINE
DCOM- 20210120
LR  - 20210120
IS  - 1550-7033 (Print)
IS  - 1550-7033 (Linking)
VI  - 16
IP  - 11
DP  - 2020 Nov 1
TI  - Techniques and Applications of Animal- and Plant-Derived Exosome-Based Drug 
      Delivery System.
PG  - 1543-1569
LID - 10.1166/jbn.2020.2993 [doi]
AB  - Exosomes are a kind of extracellular vesicle, has a particle size of 50-150 nm. 
      Exosomes derived from different cell types are thought to participate in the 
      regulation of cellular communication. On account of the ability of exosomes to 
      deliver various cargos to a corresponding target site, they are often used to 
      deliver therapeutic cargos for treatment. This review summarizes the origins and 
      composition of exosomes, and provides a detailed overview of the current methods 
      for exosome isolation and drug loading as well as the application of exosomes to 
      drug delivery systems (DDSs) to provide practical suggestions for exosome 
      studies. Moreover, this review also highlights the research progresses on 
      plant-derived exosomes in determining their commonalities with and distinctions 
      from animal-derived exosomes, and the advantages and challenges faced by 
      plant-derived exosomes as drug delivery carriers are also discussed to contribute 
      to the further application of plant-derived exosomes.
FAU - Man, Fulong
AU  - Man F
FAU - Wang, Junfeng
AU  - Wang J
FAU - Lu, Rong
AU  - Lu R
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - J Biomed Nanotechnol
JT  - Journal of biomedical nanotechnology
JID - 101230869
RN  - 0 (Drug Carriers)
SB  - IM
MH  - Animals
MH  - Cell Communication
MH  - Drug Carriers
MH  - Drug Delivery Systems
MH  - *Exosomes
MH  - Particle Size
EDAT- 2021/01/20 06:00
MHDA- 2021/01/21 06:00
CRDT- 2021/01/19 05:39
PHST- 2021/01/19 05:39 [entrez]
PHST- 2021/01/20 06:00 [pubmed]
PHST- 2021/01/21 06:00 [medline]
AID - 10.1166/jbn.2020.2993 [doi]
PST - ppublish
SO  - J Biomed Nanotechnol. 2020 Nov 1;16(11):1543-1569. doi: 10.1166/jbn.2020.2993.