PMID- 33462660 OWN - NLM STAT- MEDLINE DCOM- 20210701 LR - 20210701 IS - 1618-2650 (Electronic) IS - 1618-2642 (Linking) VI - 413 IP - 5 DP - 2021 Feb TI - Development of a highly sensitive fluorescence method for tartrazine determination in food matrices based on carbon dots. PG - 1485-1492 LID - 10.1007/s00216-020-03118-1 [doi] AB - In this work, an ultrasensitive sensing system based on fluorescent carbon dots (CDs) was developed for the tartrazine (Tar) determination. The CDs were prepared via a simple one-pot hydrothermal method with m-phenylenediamine as the only precursor. The physical and chemical properties were in detail characterized by transmission electron microscopy (TEM), MALDI-TOF MS, UV-vis absorption and photoluminescence (PL) spectroscopy, elemental analysis, and Fourier transform infrared spectroscopy (FTIR). Upon exposure to Tar, the fluorescence of CDs was efficiently quenched via the dynamic interaction between CDs and Tar as well as the inner filter effect (IFE). With this information, the CDs were proposed as a fluorescence probe for Tar detection. It was found that CDs had high sensitivity and selectivity for Tar sensing, and the linear relationship was observed in the range of 0.01-25.0 muM with the corresponding detection limit (3sigma/k) of 12.4 nM, which is much more sensitive than any of the existed CD-based sensing platform. The investigated sensing system was finally utilized for Tar sensing in various food matrices with a high degree of accuracy. The spiked recoveries were in a range of 96.4-105.2%, and the relative standard deviations (RSDs) were lower than 4.13%. This work highlights the great application prospects of CDs for Tar sensing in a rapid, simple, and sensitive way. FAU - Liu, Lingfei AU - Liu L AD - College of Food Science and Engineering, Yangzhou University, Yangzhou, 225001, Jiangsu, China. FAU - Sun, Huijuan AU - Sun H AD - College of Food Science and Engineering, Yangzhou University, Yangzhou, 225001, Jiangsu, China. FAU - Xiao, Lixia AU - Xiao L AD - College of Food Science and Engineering, Yangzhou University, Yangzhou, 225001, Jiangsu, China. lxxiao@yzu.edu.cn. FAU - Yang, Zhen-Quan AU - Yang ZQ AD - College of Food Science and Engineering, Yangzhou University, Yangzhou, 225001, Jiangsu, China. FAU - Han, Jie AU - Han J AD - School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, 225001, Jiangsu, China. FAU - Gong, Xiaojuan AU - Gong X AD - Institute of Environmental Science, and School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan, 030006, China. FAU - Hu, Qin AU - Hu Q AD - College of Food Science and Engineering, Yangzhou University, Yangzhou, 225001, Jiangsu, China. qinhu@yzu.edu.cn. AD - School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, 225001, Jiangsu, China. qinhu@yzu.edu.cn. LA - eng GR - SJCX20_1383/2020 Postgraduate Research and Practice Innovation Program of Jiangsu Province, China/ GR - 2019/LvYang Golden Phoenix Plan, Yangzhou City/ GR - 2019CXJ188/Yangzhou University Science and Technology Innovation Cultivation Fund/ GR - 2016YFC1300201/Foundation of China National Key Research & Development Program/ GR - BE2019436-5/Jiangsu Key Research & Development Program, China/ GR - KYRY2019002/Opening Foundation of Jiangsu Dairy Bioengineering Technology Research Centre/ GR - 2020M671625/China Postdoctoral Science Foundation/ GR - 20KJA550002/Natural Science Fund for Colleges and Universities in Jiangsu Province, China/ GR - 21922202/National Natural Science Foundation of China/ GR - YZ2020063/Yangzhou Key R&D Project (Social Development), China (2020)/ GR - BK20200949/Natural Science Foundation of Jiangsu Province, China/ PT - Journal Article DEP - 20210119 PL - Germany TA - Anal Bioanal Chem JT - Analytical and bioanalytical chemistry JID - 101134327 RN - 0 (Fluorescent Dyes) RN - 0 (Food Coloring Agents) RN - 7440-44-0 (Carbon) RN - I753WB2F1M (Tartrazine) SB - IM EIN - Anal Bioanal Chem. 2021 Feb 12;:. PMID: 33576856 MH - Carbon/*chemistry MH - Fluorescent Dyes/chemistry MH - Food Analysis/*methods MH - Food Coloring Agents/*analysis MH - Limit of Detection MH - Nanoparticles/*chemistry/ultrastructure MH - Spectrometry, Fluorescence/methods MH - Tartrazine/*analysis OTO - NOTNLM OT - CDs OT - Fluorescence quenching OT - Food matrices OT - Tartrazine EDAT- 2021/01/20 06:00 MHDA- 2021/07/02 06:00 CRDT- 2021/01/19 05:59 PHST- 2020/10/15 00:00 [received] PHST- 2020/12/08 00:00 [accepted] PHST- 2020/11/26 00:00 [revised] PHST- 2021/01/20 06:00 [pubmed] PHST- 2021/07/02 06:00 [medline] PHST- 2021/01/19 05:59 [entrez] AID - 10.1007/s00216-020-03118-1 [pii] AID - 10.1007/s00216-020-03118-1 [doi] PST - ppublish SO - Anal Bioanal Chem. 2021 Feb;413(5):1485-1492. doi: 10.1007/s00216-020-03118-1. Epub 2021 Jan 19.