PMID- 33463120
OWN - NLM
STAT- MEDLINE
DCOM- 20210930
LR  - 20210930
IS  - 1735-5249 (Electronic)
IS  - 1735-1502 (Linking)
VI  - 19
IP  - 5
DP  - 2020 Oct 18
TI  - The Relation of Allergy to Adenoid Hypertrophy and Otitis Media with Effusion: A 
      Cross-sectional Study.
PG  - 529-533
LID - 10.18502/ijaai.v19i5.4469 [doi]
AB  - The exact mechanisms of Adenoid hypertrophy (AHT) pathogenesis and otitis media 
      with effusion (OME) are unclear but there is increasing evidence that allergies 
      may play a role. We aimed to investigate the prevalence of atopy and the effect 
      of anti-allergic drugs in patients with AHT and OME. In a non-randomized, 
      prospective cross-sectional study, 122 patients younger than 18 years of age with 
      AHT or OME were included. Atopic patients based on clinical symptoms of allergic 
      disorders and/or elevated levels of total serum immunoglobulin E (IgE) were 
      referred to allergists and tested for allergen sensitization by skin prick test 
      (SPT). Atopic patients were treated with nasal corticosteroids and 
      antihistamines. Response to treatment was evaluated by comparing symptoms score 
      before and after the treatment. In this study 122 patients were evaluated, 116 of 
      them had AHT and 30 patients had OME. The mean age of participants was 6.7+/-2.4 
      years old and 68 of them (55.7%) were male. Allergic symptoms were observed in 38 
      patients with AHT (32.7%) and nine patients with OME (30%). Among the total 
      cases, 34 patients (28%) were considered atopic. SPT was performed on 25 (73%) 
      cases of atopic patients, with 11 (44 %) positive results. The mean symptom score 
      of AHT and OME decreased significantly after treatment respectively, (p=0.001, 
      p=0.007). According to this study, atopy was relatively common in patients with 
      AHT and OME. Treatment with nasal corticosteroid and antihistamines were 
      effective in these patients.
FAU - Bemanian, Mohammad Hassan
AU  - Bemanian MH
AD  - Department of Allergy and Clinical Immunology, Rasool e Akram Hospital, Iran 
      University of Medical Sciences, Tehran, Iran. mhbemanian@yahoo.com.
FAU - Rezaei, Kazem
AU  - Rezaei K
AD  - Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran. 
      dr_rezaee373@yahoo.com.
FAU - Atighechi, Saeid
AU  - Atighechi S
AD  - Otorhinolaryngology Research Center, Shahid Sadoughi University of Medical 
      Sciences, Yazd, Iran. ar.shafii@gmail.com.
FAU - Shafiei, Alireza
AU  - Shafiei A
AD  - Division of Allergy and Clinical Immunology, Department of Pediatrics, Bahrami 
      Hospital, Tehran University of Medical Sciences, Tehran, Iran. 
      ar.shafii@gmail.com.
LA  - eng
PT  - Journal Article
DEP - 20201018
PL  - Iran
TA  - Iran J Allergy Asthma Immunol
JT  - Iranian journal of allergy, asthma, and immunology
JID - 101146178
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adenoids/*immunology
MH  - Child
MH  - Cross-Sectional Studies
MH  - Female
MH  - Humans
MH  - Hypersensitivity/*immunology
MH  - Hypersensitivity, Immediate/immunology
MH  - Hypertrophy/*immunology
MH  - Immunoglobulin E/immunology
MH  - Male
MH  - Otitis Media/*immunology
MH  - Otitis Media with Effusion/*immunology
MH  - Prevalence
MH  - Prospective Studies
MH  - Skin Tests/methods
OTO - NOTNLM
OT  - Adenoids
OT  - Allergy
OT  - Child
OT  - Hypertrophy
OT  - Otitis media with effusion
EDAT- 2021/01/20 06:00
MHDA- 2021/10/01 06:00
CRDT- 2021/01/19 07:08
PHST- 2020/02/29 00:00 [received]
PHST- 2020/07/28 00:00 [accepted]
PHST- 2021/01/19 07:08 [entrez]
PHST- 2021/01/20 06:00 [pubmed]
PHST- 2021/10/01 06:00 [medline]
AID - 10.18502/ijaai.v19i5.4469 [doi]
PST - epublish
SO  - Iran J Allergy Asthma Immunol. 2020 Oct 18;19(5):529-533. doi: 
      10.18502/ijaai.v19i5.4469.