PMID- 33463576
OWN - NLM
STAT- MEDLINE
DCOM- 20210527
LR  - 20210527
IS  - 1998-3689 (Electronic)
IS  - 0301-4738 (Print)
IS  - 0301-4738 (Linking)
VI  - 69
IP  - 2
DP  - 2021 Feb
TI  - Ocular biometric measurements and optical coherence tomography parameters in 
      children with refractive errors and emmetropia.
PG  - 290-295
LID - 10.4103/ijo.IJO_385_20 [doi]
AB  - PURPOSE: The aim of this study was to estimate and compare the differences in 
      ocular biometric measurements (OBMs), central macular thickness (CMT), and 
      retinal nerve fiber layer thickness (RNFLT) between children with refractive 
      errors and those with emmetropia. METHODS: A cross-sectional observational study 
      of 205 children (334 eyes) aged between six and 18 years consisting of four 
      groups (emmetropia, hypermetropia, myopia, and astigmatism) was carried out. 
      Best-corrected visual acuity (BCVA), a detailed ocular examination, OBMs, 
      spectral-domain optical coherence tomography (SD OCT) for RNFLT and CMT in both 
      eyes were evaluated for each child. RESULTS: Mean age of 205 children was 12.4 +/- 
      3.2 years. 55.6% (n = 114) were girls and 44.4% (n = 91) were boys. There was a 
      significant difference between the four groups for the parameters spherical 
      equivalent (SE), keratometer readings K1and K2, axial length (AL), anterior 
      chamber depth (ACD), vitreous chamber depth (VCD) and lens thickness (LT) (P < 
      0.0001). The mean central corneal thickness (CCT) was not significantly different 
      between the four groups (P = 0.076). The mean RNFLT was thinner in the myopic 
      group compared with the emmetropic group (P = 0.0048) There was no significant 
      difference in the mean CMT across the four groups (P = 0.458). CONCLUSION: The 
      data obtained are helpful in providing the normative as well as a comparative 
      database on OBMs, RNFLT and CMT of the pediatric population. This also 
      facilitates evaluation of RNFLT and CMT measurements in children with amblyopia, 
      optic neuropathies, glaucoma, macular and retinal diseases.
FAU - Kavitha, V
AU  - Kavitha V
AD  - Department of Pediatric Ophthalmology, Services, Sankara Eye Hospital, Harakere, 
      Shimoga, Karnataka, India.
FAU - Mahesha, S
AU  - Mahesha S
AD  - Department of Trauma and Cataract, Sankara Eye Hospital, Harakere, Shimoga, 
      Karnataka, India.
FAU - Narendran, B S
AU  - Narendran BS
AD  - Sankara Eye Hospital, Krishnan Kovil, Virudhnagar, Tamil Nadu, India.
FAU - Heralgi, Mallikarjun M
AU  - Heralgi MM
AD  - Department of Cornea and Refractive Services, Sankara Eye Hospital, Harakere, 
      Shimoga, Karnataka, India.
LA  - eng
PT  - Journal Article
PT  - Observational Study
PL  - India
TA  - Indian J Ophthalmol
JT  - Indian journal of ophthalmology
JID - 0405376
SB  - IM
MH  - Adolescent
MH  - Biometry
MH  - Child
MH  - Cross-Sectional Studies
MH  - Emmetropia
MH  - Female
MH  - Humans
MH  - Male
MH  - *Refractive Errors/diagnosis
MH  - *Tomography, Optical Coherence
PMC - PMC7933838
OTO - NOTNLM
OT  - CMT
OT  - Database
OT  - RNFLT
OT  - SD OCT
OT  - ocular biometric measurements
COIS- None
EDAT- 2021/01/20 06:00
MHDA- 2021/05/28 06:00
PMCR- 2021/02/01
CRDT- 2021/01/19 08:41
PHST- 2021/01/19 08:41 [entrez]
PHST- 2021/01/20 06:00 [pubmed]
PHST- 2021/05/28 06:00 [medline]
PHST- 2021/02/01 00:00 [pmc-release]
AID - IndianJOphthalmol_2021_69_2_290_307004 [pii]
AID - IJO-69-290 [pii]
AID - 10.4103/ijo.IJO_385_20 [doi]
PST - ppublish
SO  - Indian J Ophthalmol. 2021 Feb;69(2):290-295. doi: 10.4103/ijo.IJO_385_20.