PMID- 33466588
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240330
IS  - 2077-0383 (Print)
IS  - 2077-0383 (Electronic)
IS  - 2077-0383 (Linking)
VI  - 10
IP  - 2
DP  - 2021 Jan 14
TI  - The Impact of COVID-19 on In-Hospital Outcomes of ST-Segment Elevation Myocardial 
      Infarction Patients.
LID - 10.3390/jcm10020278 [doi]
LID - 278
AB  - Primary percutaneous coronary intervention (PPCI) is one of the important 
      clinical procedures that have been affected by the COVID-19 pandemic. In this 
      study, we aimed to assess the incidence and impact of COVID-19 on in-hospital 
      clinical outcome of ST elevation myocardial infarction (STEMI) patients managed 
      with PPCI. This observational retrospective study was conducted on consecutive 
      STEMI patients who presented to the International Cardiac Center (ICC) hospital, 
      Alexandria, Egypt between 1 February and 31 October 2020. A group of STEMI 
      patients presented during the same period in 2019 was also assessed (control 
      group) and data was used for comparison. The inclusion criteria were established 
      diagnosis of STEMI requiring PPCI.A total of 634 patients were included in the 
      study. During the COVID-19 period, the number of PPCI procedures was reduced by 
      25.7% compared with previous year (mean 30.0 +/- 4.01 vs. 40.4 +/- 5.3 case/month) 
      and the time from first medical contact to Needle (FMC-to-N) was longer (125.0 +/- 
      53.6 vs. 52.6 +/- 22.8 min, p = 0.001). Also, during COVID-19, the in-hospital 
      mortality was higher (7.4 vs. 4.6%, p = 0.036) as was the incidence of 
      re-infarction (12.2 vs. 7.7%, p = 0.041) and the need for revascularization (15.9 
      vs. 10.7%, p = 0.046). The incidence of heart failure, stroke, and bleeding was 
      not different between groups, but hospital stay was longer during COVID-19 (6.85 
      +/- 4.22 vs. 3.5 +/- 2.3 day, p = 0.0025). Conclusion: At the ICC, COVID-19 pandemic 
      contributed significantly to the PPCI management of STEMI patients with decreased 
      number and delayed procedures. COVID-19 was also associated with higher 
      in-hospital mortality, rate of re-infarction, need for revascularization, and 
      longer hospital stay.
FAU - Ayad, Sherif
AU  - Ayad S
AUID- ORCID: 0000-0002-1737-0142
AD  - Faculty of Medicine, Alexandria University, Alexandria 21526, Egypt.
FAU - Shenouda, Rafik
AU  - Shenouda R
AUID- ORCID: 0000-0002-2243-2053
AD  - International Cardiac Center, Alexandria 21526, Egypt.
FAU - Henein, Michael
AU  - Henein M
AD  - Institute of Public Health and Clinical Medicine, Umea University, SE-90187 Umea, 
      Sweden.
LA  - eng
PT  - Journal Article
DEP - 20210114
PL  - Switzerland
TA  - J Clin Med
JT  - Journal of clinical medicine
JID - 101606588
PMC - PMC7828690
OTO - NOTNLM
OT  - COVID-19
OT  - ST segment elevation myocardial infarction
OT  - primary percutaneous intervention
COIS- The authors declare no conflict of interest.
EDAT- 2021/01/21 06:00
MHDA- 2021/01/21 06:01
PMCR- 2021/01/14
CRDT- 2021/01/20 01:07
PHST- 2020/12/01 00:00 [received]
PHST- 2021/01/05 00:00 [revised]
PHST- 2021/01/11 00:00 [accepted]
PHST- 2021/01/20 01:07 [entrez]
PHST- 2021/01/21 06:00 [pubmed]
PHST- 2021/01/21 06:01 [medline]
PHST- 2021/01/14 00:00 [pmc-release]
AID - jcm10020278 [pii]
AID - jcm-10-00278 [pii]
AID - 10.3390/jcm10020278 [doi]
PST - epublish
SO  - J Clin Med. 2021 Jan 14;10(2):278. doi: 10.3390/jcm10020278.