PMID- 33467225
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210122
IS  - 2411-5142 (Electronic)
IS  - 2411-5142 (Linking)
VI  - 5
IP  - 1
DP  - 2020 Jan 29
TI  - Massage Therapy Modulates Inflammatory Mediators Following Sprint Exercise in 
      Healthy Male Athletes.
LID - 10.3390/jfmk5010009 [doi]
LID - 9
AB  - Massage therapy is a common postexercise muscle recovery modality; however, its 
      mechanisms of efficacy are uncertain. We evaluated the effects of massage on 
      systemic inflammatory responses to exercise and postexercise muscle performance 
      and soreness. In this crossover study, nine healthy male athletes completed a 
      high-intensity intermittent sprint protocol, followed by massage therapy or 
      control condition. Inflammatory markers were assessed pre-exercise; postexercise; 
      and at 1, 2, and 24 h postexercise. Muscle performance was measured by squat and 
      drop jump, and muscle soreness on a Likert scale. Significant time effects were 
      observed for monocyte chemoattractant protein-1 (MCP-1), interleukin-8 (IL-8), 
      interleukin-6 (IL-6), interleukin-10 (IL-10), tumor necrosis factor alpha (TNFalpha), 
      drop jump performance, squat jump performance, and soreness. No significant 
      effects for condition were observed. However, compared with control, inflammatory 
      marker concentrations (IL-8, TNFalpha, and MCP-1) returned to baseline levels earlier 
      following the massage therapy condition (p < 0.05 for all). IL-6 returned to 
      baseline levels earlier following the control versus massage therapy condition (p 
      < 0.05). No differences were observed for performance or soreness variables. 
      MCP-1 area under the curve (AUC) was negatively associated with squat and drop 
      jump performance, while IL-10 AUC was positively associated with drop jump 
      performance (p < 0.05 for all). In conclusion, massage therapy promotes 
      resolution of systemic inflammatory signaling following exercise but does not 
      appear to improve performance or soreness measurements.
FAU - White, Gillian E
AU  - White GE
AD  - Graduate Department of Exercise Sciences, University of Toronto, Toronto, ON M5S 
      2W6, Canada.
AD  - Translational Medicine, The Hospital for Sick Children, Toronto, ON M5G 1X8, 
      Canada.
FAU - West, Sarah L
AU  - West SL
AD  - Translational Medicine, The Hospital for Sick Children, Toronto, ON M5G 1X8, 
      Canada.
AD  - Department of Biology & Trent/Fleming School of Nursing, Trent University, 
      Peterborough, ON K9L 0G2, Canada.
FAU - Caterini, Jessica E
AU  - Caterini JE
AUID- ORCID: 0000-0002-4065-0775
AD  - Graduate Department of Exercise Sciences, University of Toronto, Toronto, ON M5S 
      2W6, Canada.
AD  - Translational Medicine, The Hospital for Sick Children, Toronto, ON M5G 1X8, 
      Canada.
FAU - Di Battista, Alex P
AU  - Di Battista AP
AD  - Graduate Department of Exercise Sciences, University of Toronto, Toronto, ON M5S 
      2W6, Canada.
AD  - Defence Research and Development Canada, Toronto Research Centre, Toronto, ON M3K 
      2C9, Canada.
FAU - Rhind, Shawn G
AU  - Rhind SG
AUID- ORCID: 0000-0003-2300-0620
AD  - Graduate Department of Exercise Sciences, University of Toronto, Toronto, ON M5S 
      2W6, Canada.
AD  - Defence Research and Development Canada, Toronto Research Centre, Toronto, ON M3K 
      2C9, Canada.
FAU - Wells, Greg D
AU  - Wells GD
AD  - Translational Medicine, The Hospital for Sick Children, Toronto, ON M5G 1X8, 
      Canada.
LA  - eng
GR  - 497640/Massage Therapy Research Fund/
PT  - Journal Article
DEP - 20200129
PL  - Switzerland
TA  - J Funct Morphol Kinesiol
JT  - Journal of functional morphology and kinesiology
JID - 101712257
PMC - PMC7739334
OTO - NOTNLM
OT  - exercise
OT  - inflammation
OT  - massage therapy
OT  - recovery
COIS- All authors declare no conflicts of interest.
EDAT- 2021/01/21 06:00
MHDA- 2021/01/21 06:01
PMCR- 2020/01/29
CRDT- 2021/01/20 01:08
PHST- 2019/12/11 00:00 [received]
PHST- 2020/01/17 00:00 [revised]
PHST- 2020/01/22 00:00 [accepted]
PHST- 2021/01/20 01:08 [entrez]
PHST- 2021/01/21 06:00 [pubmed]
PHST- 2021/01/21 06:01 [medline]
PHST- 2020/01/29 00:00 [pmc-release]
AID - jfmk5010009 [pii]
AID - jfmk-05-00009 [pii]
AID - 10.3390/jfmk5010009 [doi]
PST - epublish
SO  - J Funct Morphol Kinesiol. 2020 Jan 29;5(1):9. doi: 10.3390/jfmk5010009.