PMID- 33468265
OWN - NLM
STAT- MEDLINE
DCOM- 20220128
LR  - 20220128
IS  - 1475-2662 (Electronic)
IS  - 0007-1145 (Print)
IS  - 0007-1145 (Linking)
VI  - 126
IP  - 9
DP  - 2021 Nov 14
TI  - Feeding intolerance and risk of poor outcome in patients undergoing 
      cardiopulmonary bypass surgery.
PG  - 1340-1346
LID - 10.1017/S0007114521000167 [doi]
AB  - We conducted a prospective, observational study to determine the incidence of 
      feeding intolerance (FI) within 7 d of initiating enteral nutrition (EN) in 
      patients undergoing cardiopulmonary bypass (CPB) and to evaluate the association 
      between FI and a poor prognosis. Patients who underwent CPB surgery at Fujian 
      Medical University Union Hospital between March 2020 and June 2020 were enrolled. 
      According to the presence or absence of FI within 7 d after EN, patients were 
      divided into FI and non-FI groups. According to the occurrence of a poor 
      prognosis (death, gastrointestinal haemorrhage, acute kidney injury, liver 
      insufficiency, neurological events (cerebral infarction, cerebral haemorrhage and 
      epilepsy) and prolonged mechanical ventilation (> 48 h)), patients were divided 
      into poor prognosis and good prognosis groups. The mean age of the 237 CPB 
      patients, including 139 men and ninety-eight women, was 53.80 (sd 12.25) years. 
      The incidence of FI was 64.14 %. Multivariate logistic regression analysis showed 
      factors independently associated with poor prognosis after CPB included FI (OR 
      2.138; 95 % CI 1.058, 4.320), age (OR 1.033; 95 % CI 1.004, 1.063), New York 
      Heart Association (NYHA) class III/IV cardiac function (OR 2.410; 95 % CI 1.079, 
      5.383), macrovascular surgery (OR 5.434; 95 % CI 1.704, 17.333) and initial 
      sequential organ failure assessment score (OR 1.243; 95 % CI 1.010, 1.530). Thus, 
      the incidence of FI within 7 d of EN after CPB was high, which was associated 
      with a poor prognosis.
FAU - Lin, Yanjuan
AU  - Lin Y
AD  - Department of Nursing, Fujian Medical University Union Hospital, 29 Xinquan Road, 
      Fuzhou City, Fujian Province, People's Republic of China.
FAU - Chen, Meihua
AU  - Chen M
AD  - Department of Cardiac Surgery, Fujian Medical University Union Hospital, 29 
      Xinquan Road, Fuzhou City, Fujian Province, People's Republic of China.
FAU - Peng, Yanchun
AU  - Peng Y
AD  - Department of Cardiac Surgery, Fujian Medical University Union Hospital, 29 
      Xinquan Road, Fuzhou City, Fujian Province, People's Republic of China.
FAU - Chen, Qiong
AU  - Chen Q
AD  - Fujian Medical University, 88 Jiaotong Road, Fuzhou City, Fujian Province, 
      People's Republic of China.
FAU - Li, Sailan
AU  - Li S
AD  - Department of Cardiac Surgery, Fujian Medical University Union Hospital, 29 
      Xinquan Road, Fuzhou City, Fujian Province, People's Republic of China.
FAU - Chen, Liangwan
AU  - Chen L
AD  - Department of Cardiac Surgery, Fujian Medical University Union Hospital, 29 
      Xinquan Road, Fuzhou City, Fujian Province, People's Republic of China.
LA  - eng
PT  - Journal Article
PT  - Observational Study
PT  - Research Support, Non-U.S. Gov't
DEP - 20210120
PL  - England
TA  - Br J Nutr
JT  - The British journal of nutrition
JID - 0372547
SB  - IM
MH  - Adult
MH  - Aged
MH  - *Cardiopulmonary Bypass/adverse effects
MH  - Enteral Nutrition
MH  - Female
MH  - *Food Intolerance
MH  - Humans
MH  - Incidence
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
PMC - PMC8505710
OTO - NOTNLM
OT  - Cardiopulmonary bypass surgery
OT  - Enteral nutrition
OT  - Feeding intolerance
OT  - Poor prognosis
EDAT- 2021/01/21 06:00
MHDA- 2022/01/29 06:00
PMCR- 2021/10/12
CRDT- 2021/01/20 05:38
PHST- 2021/01/21 06:00 [pubmed]
PHST- 2022/01/29 06:00 [medline]
PHST- 2021/01/20 05:38 [entrez]
PHST- 2021/10/12 00:00 [pmc-release]
AID - S0007114521000167 [pii]
AID - 10.1017/S0007114521000167 [doi]
PST - ppublish
SO  - Br J Nutr. 2021 Nov 14;126(9):1340-1346. doi: 10.1017/S0007114521000167. Epub 
      2021 Jan 20.