PMID- 33468769 OWN - NLM STAT- MEDLINE DCOM- 20210121 LR - 20210121 IS - 0385-0684 (Print) IS - 0385-0684 (Linking) VI - 47 IP - 13 DP - 2020 Dec TI - [Long-Term Recurrence-Free Survival in a Patient Who Received Chemotherapy for Multiple Metastases of Rectal Cancer Including the Lesser-Curvature Lymph Node Metastasis-A Case Report]. PG - 1969-1971 AB - A 49-year-old man was preoperatively diagnosed with rectosigmoid carcinoma, c-T4a, N3, M1b, Stage Ⅳb. On CT, lymph node swelling outside that area, including lesser-curvature lymph nodes(LNS), and liver metastases were seen. Laparoscopic high anterior resection was performed with the aim of local control. Additionally, D3 dissection and LNS sampling were performed. The tumor had invaded the bladder wall, and removed LNS were positive for metastasis. The final diagnosis was f-T4b, N3, M1b, Stage Ⅳb. One month after surgery, a CV port was implanted, and chemotherapy was initiated for unresectable cancer. The regimen was capecitabine and oxaliplatin(CAPOX)plus bevacizumab(BEV). After 5 courses, the patient was hospitalized for a CV thrombus that had occurred, and his chemotherapy was withdrawn for approximately 1 month while he was receiving antithrombotic therapy. After discharge, BEV was discontinued, and he received CAPOX alone. Bleeding from a pituitary adenoma was seen after a total of 19 courses. He was hospitalized for 2 months for the treatment, including surgery. A clinical complete response was determined based on CT and PET-CT performed after chemotherapy had been withdrawn for approximately 3 months. For approximately 1 year since the chemotherapy was discontinued, progression-free survival has been maintained. FAU - Yamada, Erika AU - Yamada E AD - Dept. of Gastrointestinal and Pediatric Surgery, Tokyo Medical University. FAU - Enomoto, Masanobu AU - Enomoto M FAU - Ishizaki, Tetsuo AU - Ishizaki T FAU - Mazaki, Junichi AU - Mazaki J FAU - Wada, Takahiro AU - Wada T FAU - Watanabe, Mitsuru AU - Watanabe M FAU - Kasahara, Kenta AU - Kasahara K FAU - Ohno, Yuki AU - Ohno Y FAU - Takano, Yuki AU - Takano Y FAU - Nagakawa, Yuichi AU - Nagakawa Y FAU - Katsumata, Kenji AU - Katsumata K FAU - Tsuchida, Akihiko AU - Tsuchida A LA - jpn PT - Case Reports PT - Journal Article PL - Japan TA - Gan To Kagaku Ryoho JT - Gan to kagaku ryoho. Cancer & chemotherapy JID - 7810034 RN - 6804DJ8Z9U (Capecitabine) SB - IM MH - Antineoplastic Combined Chemotherapy Protocols/therapeutic use MH - Capecitabine/therapeutic use MH - Humans MH - Lymph Nodes MH - Lymphatic Metastasis MH - Male MH - Middle Aged MH - *Positron Emission Tomography Computed Tomography MH - *Rectal Neoplasms/drug therapy/surgery EDAT- 2021/01/21 06:00 MHDA- 2021/01/22 06:00 CRDT- 2021/01/20 05:44 PHST- 2021/01/20 05:44 [entrez] PHST- 2021/01/21 06:00 [pubmed] PHST- 2021/01/22 06:00 [medline] PST - ppublish SO - Gan To Kagaku Ryoho. 2020 Dec;47(13):1969-1971.