PMID- 33472499
OWN - NLM
STAT- MEDLINE
DCOM- 20210624
LR  - 20230919
IS  - 2150-1327 (Electronic)
IS  - 2150-1319 (Print)
IS  - 2150-1319 (Linking)
VI  - 12
DP  - 2021 Jan-Dec
TI  - The Impact of the Indonesian Chronic Disease Management Program (PROLANIS) on 
      Metabolic Control and Renal Function of Type 2 Diabetes Mellitus Patients in 
      Primary Care Setting.
PG  - 2150132720984409
LID - 10.1177/2150132720984409 [doi]
LID - 2150132720984409
AB  - BACKGROUND: Indonesia through its government National Health Insurance System has 
      launched a non-communicable and chronic disease management program named 
      Indonesian Chronic Disease Management Program (PROLANIS), with Type 2 Diabetes 
      Mellitus (T2DM) and hypertension as the main focus. However, study that evaluates 
      the clinical impact of PROLANIS in patients with T2DM is still scarce to this 
      date. This study aims to evaluate the metabolic control and renal function of 
      PROLANIS participants with T2DM every six month within the first 18-months of 
      implementation. METHODS: This study was a retrospective cohort study conducted at 
      Wates sub-district, East Java using secondary data from PROLANIS group report 
      from April 2018 to October 2019. The study population was T2DM patients who 
      voluntarily joined the PROLANIS group in April 2018. The six-month-evaluation 
      included metabolic parameters [body mass index (BMI), blood pressure, hemoglobin 
      A1C, total cholesterol, high-density lipid, low-density lipid, and triglyceride 
      (TG)] and renal parameters [blood urea nitrogen (BUN), creatinine serum, and 
      urinary microalbumin]. Paired t-test and wilcoxon signed-rank test was used for 
      the analysis, and the P-value was adjusted using Bonferroni correction. A 
      P-value < .0015 was considered statistically significant, while a P-value between 
      .0015 and .003 was considered as marginally significant. RESULTS: A total of 30 
      participants were included in the analysis. Following the PROLANIS 
      implementation, the only parameter of metabolic control that showed significant 
      improvement was TG serum level (P < .001). Despite the worsening status of other 
      metabolic parameters, the changes were not statistically significant except for 
      BMI that was marginally significant (P = .002). From renal function, only BUN 
      serum level was significantly deteriorated (P < .001), while the others did not 
      significantly change. CONCLUSION: PROLANIS implementation in our study population 
      seems to be ineffective. Future study with more primary healthcare centers needs 
      to be done to scrutinize the clinical impact of this program nationwide.
FAU - Alkaff, Firas Farisi
AU  - Alkaff FF
AUID- ORCID: 0000-0002-5628-1345
AD  - Department of Pharmacology and Therapy, Faculty of Medicine Universitas 
      Airlangga, Surabaya, East Java, Indonesia.
FAU - Illavi, Fauzan
AU  - Illavi F
AD  - Department of Internal Medicine, Dr.Cipto Mangunkusumo General Hospital, Faculty 
      of Medicine Universitas Indonesia, Central Jakarta, Jakarta, Indonesia.
FAU - Salamah, Sovia
AU  - Salamah S
AD  - Department of Public Health and Preventive Medicine, Faculty of Medicine 
      Universitas Airlangga, Surabaya, East Java, Indonesia.
FAU - Setiyawati, Wiwit
AU  - Setiyawati W
AD  - Faculty of Medicine Universitas Airlangga, Surabaya, East Java, Indonesia.
FAU - Ramadhani, Ristra
AU  - Ramadhani R
AD  - Faculty of Medicine Universitas Airlangga, Surabaya, East Java, Indonesia.
FAU - Purwantini, Elly
AU  - Purwantini E
AD  - Politeknik Elektronika Negeri Surabaya, Surabaya, East Java, Indonesia.
FAU - Tahapary, Dicky L
AU  - Tahapary DL
AD  - Department of Internal Medicine, Dr.Cipto Mangunkusumo General Hospital, Faculty 
      of Medicine Universitas Indonesia, Central Jakarta, Jakarta, Indonesia.
AD  - Metabolic, Cardiovascular, and Aging Cluster, The Indonesian Medical Education 
      and Research Institute,Faculty of Medicine Universitas Indonesia, Central 
      Jakarta, Jakarta, Indonesia.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Prim Care Community Health
JT  - Journal of primary care & community health
JID - 101518419
RN  - 0 (Glycated Hemoglobin A)
SB  - IM
MH  - *Diabetes Mellitus, Type 2/therapy
MH  - Disease Management
MH  - Glycated Hemoglobin/analysis
MH  - Humans
MH  - Indonesia
MH  - Primary Health Care
MH  - Retrospective Studies
PMC - PMC7829517
OTO - NOTNLM
OT  - Indonesia
OT  - PROLANIS
OT  - government program
OT  - primary healthcare
OT  - type 2 diabetes mellitus
COIS- Declaration of Conflicting Interests: The author(s) declared no potential 
      conflicts of interest with respect to the research, authorship, and/or 
      publication of this article.
EDAT- 2021/01/22 06:00
MHDA- 2021/06/25 06:00
PMCR- 2021/01/20
CRDT- 2021/01/21 05:23
PHST- 2021/01/21 05:23 [entrez]
PHST- 2021/01/22 06:00 [pubmed]
PHST- 2021/06/25 06:00 [medline]
PHST- 2021/01/20 00:00 [pmc-release]
AID - 10.1177_2150132720984409 [pii]
AID - 10.1177/2150132720984409 [doi]
PST - ppublish
SO  - J Prim Care Community Health. 2021 Jan-Dec;12:2150132720984409. doi: 
      10.1177/2150132720984409.