PMID- 33478335
OWN - NLM
STAT- MEDLINE
DCOM- 20211123
LR  - 20211123
IS  - 1533-0338 (Electronic)
IS  - 1533-0346 (Print)
IS  - 1533-0338 (Linking)
VI  - 20
DP  - 2021 Jan-Dec
TI  - Diagnostic Value of Virtual Bronchoscopic Navigation Combined With Endobronchial 
      Ultrasound Guided Transbronchial Lung Biopsy for Peripheral Pulmonary Lesions.
PG  - 1533033821989992
LID - 10.1177/1533033821989992 [doi]
LID - 1533033821989992
AB  - OBJECTIVE: X-ray guided transbronchial ultrasound-guided transbronchial lung 
      biopsy (EBUS-TBLB) can improve the diagnostic yield of peripheral pulmonary 
      lesions (PPLs), but it needs special requirements. The purpose of this study was 
      to investigate the clinical value of virtual bronchoscopy navigation (VBN) 
      combined with EBUS-TBLB in the diagnosis of PPLs without X-ray guidance. METHODS: 
      The 105 patients with PPLs underwent EBUS-TBLB with or without VBN randomly. The 
      diagnostic yield, the operation time and complications were evaluated in the 2 
      groups. RESULTS: No significant difference was found between the VBN+EBUS group 
      and the EBUS group (76.0% vs. 65.5%, P = 0.287). The operation time of VBN+EBUS 
      group was significantly shorter than that of EBUS group (20.6 +/- 12.8 min vs. 28.6 
      +/- 14.3 min, P = 0.023). No severe procedure related complications occurred. 
      CONCLUSIONS: VBN can shorten the operation time. The combination of VBN and 
      EBUS-TBLB is a safe and effective diagnosis technique for PPLs.
FAU - Xu, Chunhua
AU  - Xu C
AUID- ORCID: 0000-0001-8728-2183
AD  - Department of Respiratory Medicine, The Affiliated Brain Hospital of Nanjing 
      Medical University, Nanjing, Jiangsu, China.
AD  - Clinical Center of Nanjing Respiratory Diseases and Imaging, Nanjing, Jiangsu, 
      China.
FAU - Wang, Yan
AU  - Wang Y
AD  - Department of Echocardiography, The Affiliated Brain Hospital of Nanjing Medical 
      University, Nanjing, Jiangsu, China.
FAU - Li, Li
AU  - Li L
AD  - Department of Respiratory Medicine, The Affiliated Brain Hospital of Nanjing 
      Medical University, Nanjing, Jiangsu, China.
AD  - Clinical Center of Nanjing Respiratory Diseases and Imaging, Nanjing, Jiangsu, 
      China.
FAU - Yuan, Qi
AU  - Yuan Q
AD  - Department of Respiratory Medicine, The Affiliated Brain Hospital of Nanjing 
      Medical University, Nanjing, Jiangsu, China.
AD  - Clinical Center of Nanjing Respiratory Diseases and Imaging, Nanjing, Jiangsu, 
      China.
FAU - Wang, Yuchao
AU  - Wang Y
AD  - Department of Respiratory Medicine, The Affiliated Brain Hospital of Nanjing 
      Medical University, Nanjing, Jiangsu, China.
AD  - Clinical Center of Nanjing Respiratory Diseases and Imaging, Nanjing, Jiangsu, 
      China.
FAU - Hu, Huidi
AU  - Hu H
AD  - Department of Pathology, The Affiliated Brain Hospital of Nanjing Medical 
      University, Nanjing, Jiangsu, China.
FAU - Zhang, Xiuwei
AU  - Zhang X
AD  - Department of Respiratory Medicine, The Affiliated Jiangning Hospital of Nanjing 
      Medical University, Jiangsu, China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Technol Cancer Res Treat
JT  - Technology in cancer research & treatment
JID - 101140941
RN  - 0 (Biomarkers)
SB  - IM
MH  - Aged
MH  - Biomarkers
MH  - Bronchoscopy/adverse effects/*methods
MH  - Diagnosis, Differential
MH  - Disease Management
MH  - Endosonography/drug effects/*methods
MH  - Female
MH  - Histocytochemistry
MH  - Humans
MH  - Image-Guided Biopsy/adverse effects/*methods
MH  - Lung Diseases/*diagnostic imaging/*pathology
MH  - Male
MH  - Middle Aged
MH  - Tomography, X-Ray Computed
PMC - PMC7841853
OTO - NOTNLM
OT  - diagnosis
OT  - endobronchial ultrasound
OT  - peripheral pulmonary lesions
OT  - transbronchial lung biopsy
OT  - virtual bronchoscopic navigation
COIS- Declaration of Conflicting Interests: The author(s) declared no potential 
      conflicts of interest with respect to the research, authorship, and/or 
      publication of this article.
EDAT- 2021/01/23 06:00
MHDA- 2021/11/24 06:00
PMCR- 2021/01/22
CRDT- 2021/01/22 05:43
PHST- 2021/01/22 05:43 [entrez]
PHST- 2021/01/23 06:00 [pubmed]
PHST- 2021/11/24 06:00 [medline]
PHST- 2021/01/22 00:00 [pmc-release]
AID - 10.1177_1533033821989992 [pii]
AID - 10.1177/1533033821989992 [doi]
PST - ppublish
SO  - Technol Cancer Res Treat. 2021 Jan-Dec;20:1533033821989992. doi: 
      10.1177/1533033821989992.