PMID- 33480194
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240330
IS  - 1738-6586 (Print)
IS  - 2005-5013 (Electronic)
IS  - 1738-6586 (Linking)
VI  - 17
IP  - 1
DP  - 2021 Jan
TI  - Treatments for Convulsive and Nonconvulsive Status Epilepticus in Adults: An 
      Expert Opinion Survey in South Korea.
PG  - 20-25
LID - 10.3988/jcn.2021.17.1.20 [doi]
AB  - BACKGROUND AND PURPOSE: The aim of this study was to survey the expert opinions 
      on treatments for convulsive status epilepticus (CSE) and nonconvulsive status 
      epilepticus (NCSE) in adults. METHODS: Forty-two South Korean epileptologists 
      participated in this survey. They completed an online questionnaire regarding 
      various patient scenarios and evaluated the appropriateness of medications used 
      to treat CSE and NCSE. RESULTS: Initial treatment with a benzodiazepine (BZD) 
      followed by either a second BZD or an antiepileptic drug (AED) monotherapy was 
      the preferred treatment strategy. More than two-thirds of the experts used a 
      second BZD when the first one failed, and consensus was reached for 84.8% of the 
      survey items. The preferred BZD was intravenous (IV) lorazepam for the initial 
      treatment of status epilepticus. IV fosphenytoin and IV levetiracetam were chosen 
      for AED monotherapy after the failure of BZD. The treatments for NCSE were 
      similar to those for CSE. Continuous IV midazolam infusion was the treatment of 
      choice for iatrogenic coma in refractory CSE, but other AEDs were preferred over 
      iatrogenic coma in refractory NCSE. CONCLUSIONS: The results of this survey are 
      consistent with previous guidelines, and can be cautiously applied in clinical 
      practice when treating patients with CSE or NCSE.
CI  - Copyright (c) 2021 Korean Neurological Association.
FAU - Byun, Jung Ick
AU  - Byun JI
AUID- ORCID: 0000-0002-6224-4575
AD  - Department of Neurology, Kyung Hee University Hospital at Gangdong, Kyung Hee 
      University, School of Medicine, Seoul, Korea.
FAU - Kim, Dong Wook
AU  - Kim DW
AUID- ORCID: 0000-0003-4484-0602
AD  - Department of Neuroloy, Konkuk University School of Medicine, Seoul, Korea.
FAU - Kim, Keun Tae
AU  - Kim KT
AUID- ORCID: 0000-0002-7124-0736
AD  - Department of Neurology, Keimyung University School of Medicine, Daegu, Korea.
FAU - Yang, Kwang Ik
AU  - Yang KI
AUID- ORCID: 0000-0001-6343-6520
AD  - Department of Neurology, Soonchunhyang University College of Medicine, Cheonan 
      Hospital, Cheonan, Korea.
FAU - Lee, Soon Tae
AU  - Lee ST
AUID- ORCID: 0000-0003-4767-7564
AD  - Department of Neurology, Seoul National University Hospital, Seoul National 
      University College of Medicine, Seoul, Korea.
FAU - Seo, Jong Geun
AU  - Seo JG
AUID- ORCID: 0000-0002-3944-5731
AD  - Department of Neurology, School of Medicine, Kyungpook National University, 
      Daegu, Korea.
FAU - No, Young Joo
AU  - No YJ
AUID- ORCID: 0000-0002-0145-5707
AD  - Department of Neurology, Samsung Noble County, Yongin, Korea.
FAU - Kang, Kyung Wook
AU  - Kang KW
AUID- ORCID: 0000-0001-9362-8670
AD  - Department of Neurology, Chonnam National University Hospital, Chonnam National 
      University School of Medicine, Gwangju, Korea.
FAU - Kim, Daeyoung
AU  - Kim D
AUID- ORCID: 0000-0001-9056-0017
AD  - Department of Neurology, Chungnam National University Hospital, Daejeon, Korea.
FAU - Cho, Yong Won
AU  - Cho YW
AUID- ORCID: 0000-0002-6127-1045
AD  - Department of Neurology, Keimyung University School of Medicine, Daegu, Korea. 
      neurocho@gmail.com.
FAU - Kim, Jae Moon
AU  - Kim JM
AUID- ORCID: 0000-0002-5035-9877
AD  - Department of Neurology, Chungnam National University Hospital, Daejeon, Korea. 
      jmoonkim@cnu.ac.kr.
CN  - Drug Committee of Korean Epilepsy Society
LA  - eng
PT  - Journal Article
PL  - Korea (South)
TA  - J Clin Neurol
JT  - Journal of clinical neurology (Seoul, Korea)
JID - 101252374
PMC - PMC7840316
OTO - NOTNLM
OT  - consensus
OT  - nonconvulsive status epilepticus
OT  - status epilepticus
OT  - treatment
COIS- The authors have no potential conflicts of interest to disclose.
EDAT- 2021/01/23 06:00
MHDA- 2021/01/23 06:01
PMCR- 2021/01/01
CRDT- 2021/01/22 06:32
PHST- 2020/04/13 00:00 [received]
PHST- 2020/07/27 00:00 [revised]
PHST- 2020/07/29 00:00 [accepted]
PHST- 2021/01/22 06:32 [entrez]
PHST- 2021/01/23 06:00 [pubmed]
PHST- 2021/01/23 06:01 [medline]
PHST- 2021/01/01 00:00 [pmc-release]
AID - 17.20 [pii]
AID - 10.3988/jcn.2021.17.1.20 [doi]
PST - ppublish
SO  - J Clin Neurol. 2021 Jan;17(1):20-25. doi: 10.3988/jcn.2021.17.1.20.