PMID- 33482523
OWN - NLM
STAT- MEDLINE
DCOM- 20211105
LR  - 20211105
IS  - 1878-0334 (Electronic)
IS  - 1871-4021 (Linking)
VI  - 15
IP  - 1
DP  - 2021 Jan-Feb
TI  - Exercise as a complementary medicine intervention in type 2 diabetes mellitus: A 
      systematic review with narrative and qualitative synthesis of evidence.
PG  - 273-286
LID - S1871-4021(21)00010-2 [pii]
LID - 10.1016/j.dsx.2021.01.008 [doi]
AB  - BACKGROUND AND AIMS: Type 2 diabetes mellitus (T2DM) is a rapidly growing public 
      health issue. This systematic review aimed to narrate and qualitatively 
      synthesize evidence and recommendations of physical activity/exercise for 
      patients with T2DM. METHODS: The databases Medline through Pubmed, Cochrane, and 
      Scopus were systematically searched from inception to February 08, 2020 using 
      MeSH terms related to "diabetes mellitus" and "physical activity/exercise". 
      Studies were included if they reported on the roles of physical activity/exercise 
      in managing patients with T2DM or effects of physical activity/exercise on 
      glycemic control. Documents identified through the search were analyzed and 
      evidence and recommendations were synthesized qualitatively. RESULTS: Data were 
      extracted from 16 original articles and 11 systematic reviews with meta-analyses. 
      A qualitative summary of evidence included general items (n = 6) and 
      recommendations for physical activity/exercise (n = 12). Physical 
      activity/exercise can reduce incidence of T2DM, hyperinsulinemia, fasting 
      plasma/blood glucose, HbA1c, body fats, cholesterol, blood pressure, heart rate, 
      cardiovascular risk, and dosage of antidiabetic medications. Physical 
      activity/exercise can improve sensitivity to insulin, muscle strength, oxygen 
      consumption, aerobic capacity, and mental health of patients with T2DM. 
      CONCLUSION: Despite the increasing interest in incorporating physical 
      activity/exercise in the management of T2DM and improving healthcare delivery, 
      there are still limited clear instructions and guidelines for both the patient 
      and the healthcare provider.
CI  - Copyright (c) 2021 Diabetes India. Published by Elsevier Ltd. All rights reserved.
FAU - Shawahna, Ramzi
AU  - Shawahna R
AD  - Department of Physiology, Pharmacology and Toxicology, Faculty of Medicine and 
      Health Sciences, An-Najah National University, Nablus, Palestine; An-Najah 
      BioSciences Unit, Centre for Poisons Control, Chemical and Biological Analyses, 
      An-Najah National University, Nablus, Palestine. Electronic address: 
      ramzi_shawahna@hotmail.com.
FAU - Batta, Ahmad
AU  - Batta A
AD  - Department of Medicine, Faculty of Medicine and Health Sciences, An-Najah 
      National University, Nablus, Palestine.
FAU - Asa'ad, Mahmoud
AU  - Asa'ad M
AD  - Department of Medicine, Faculty of Medicine and Health Sciences, An-Najah 
      National University, Nablus, Palestine.
FAU - Jomaah, Marwan
AU  - Jomaah M
AD  - Department of Medicine, Faculty of Medicine and Health Sciences, An-Najah 
      National University, Nablus, Palestine.
FAU - Abdelhaq, Imad
AU  - Abdelhaq I
AD  - Department of Physical Education, Faculty of Educational Sciences and Teachers' 
      Training, An-Najah National University, Nablus, Palestine.
LA  - eng
PT  - Journal Article
PT  - Systematic Review
DEP - 20210113
PL  - Netherlands
TA  - Diabetes Metab Syndr
JT  - Diabetes & metabolic syndrome
JID - 101462250
SB  - IM
MH  - Complementary Therapies
MH  - Diabetes Mellitus, Type 2/*therapy
MH  - Evaluation Studies as Topic
MH  - *Exercise
MH  - Humans
OTO - NOTNLM
OT  - Complementary therapy
OT  - Diabetes
OT  - Exercise
OT  - Physical activity
OT  - Type 2 diabetes
COIS- Declaration of competing interest The authors declare that they have no competing 
      interests.
EDAT- 2021/01/23 06:00
MHDA- 2021/11/06 06:00
CRDT- 2021/01/22 20:13
PHST- 2020/12/14 00:00 [received]
PHST- 2021/01/02 00:00 [revised]
PHST- 2021/01/07 00:00 [accepted]
PHST- 2021/01/23 06:00 [pubmed]
PHST- 2021/11/06 06:00 [medline]
PHST- 2021/01/22 20:13 [entrez]
AID - S1871-4021(21)00010-2 [pii]
AID - 10.1016/j.dsx.2021.01.008 [doi]
PST - ppublish
SO  - Diabetes Metab Syndr. 2021 Jan-Feb;15(1):273-286. doi: 10.1016/j.dsx.2021.01.008. 
      Epub 2021 Jan 13.