PMID- 33482838
OWN - NLM
STAT- MEDLINE
DCOM- 20211029
LR  - 20211029
IS  - 1477-7827 (Electronic)
IS  - 1477-7827 (Linking)
VI  - 19
IP  - 1
DP  - 2021 Jan 22
TI  - Predictive value of live birth rate based on different intrauterine adhesion 
      evaluation systems following TCRA.
PG  - 13
LID - 10.1186/s12958-021-00697-1 [doi]
LID - 13
AB  - OBJECTIVE: The aim of this study was to assess the predictive value of five 
      different intrauterine adhesion (IUA) evaluation systems for live birth rate 
      following transcervical resection of adhesion (TCRA). METHOD: This retrospective 
      study included 128 women with IUA who desired for spontaneous conception after 
      TCRA. All the patients were retrospectively scored by the American Fertility 
      Society (AFS) classification, European Society of Gynecological Endoscopy (ESGE) 
      classification, March's classification (March), Nasr classification (Nasr) and 
      Chinese IUA diagnosis classification criteria (Chinese). The predictive value of 
      these evaluation systems was determined by receiver operating characteristic 
      (ROC) curves and area under a ROC curve (AUC). RESULTS: The correlation 
      coefficients of AFS, ESGE, March, Nasr and Chinese classification and the live 
      birth rate were 0.313, 0.313, 0.288, 0.380, and 0.336, respectively. Among women 
      with hypomenorrhea and amenorrhea, as well as women with no infertility, the 
      severities determined by all five evaluation systems were correlated with live 
      birth rate (P <  0.001). All five scoring systems were efficient to predict live 
      birth rate. Among them, Nasr classification showed the highest AUC (0.748) with 
      the best predictive value. Multivariate logistic regression analyses showed that 
      Nasr classification had the highest OR (OR, 6.523; 95% CI, 2.612, 18.263). And, 
      Nasr's classification system also showed highest sensitivity (81.8%) and negative 
      predictive value (96.7%) when divide the system into mild IUA vs. moderate and 
      severe IUA. CONCLUSION: AFS, ESGE, March, Nasr and Chinese classification were 
      demonstrated to be capable of predicting live birth following TCRA although the 
      predictive capacities might be limited, and Nasr classification showed the 
      highest predictive value of live birth.
FAU - Cao, Mingzhu
AU  - Cao M
AD  - Department of Obstetrics and Gynecology, Center for Reproductive Medicine, Key 
      Laboratory for Major Obstetric Diseases of Guangdong Province, The Third 
      Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
FAU - Pan, Yingying
AU  - Pan Y
AD  - Department of Ultrasound, Nanfang Hospital, Southern Medical University, 
      Guangzhou, 510515, China.
AD  - The First School of Clinical Medicine, Southern Medical University, Guangzhou, 
      China.
FAU - Zhang, Qingyan
AU  - Zhang Q
AD  - Department of Ultrasound, Nanfang Hospital, Southern Medical University, 
      Guangzhou, 510515, China.
AD  - The First School of Clinical Medicine, Southern Medical University, Guangzhou, 
      China.
FAU - You, Danming
AU  - You D
AD  - Department of Ultrasound, Nanfang Hospital, Southern Medical University, 
      Guangzhou, 510515, China.
AD  - The First School of Clinical Medicine, Southern Medical University, Guangzhou, 
      China.
FAU - Feng, Shuying
AU  - Feng S
AD  - Department of Obstetrics and Gynecology, Sun Yat-sen Memorial Hospital, Sun 
      Yat-sen University, Guangzhou, 510120, China. fengshuying@263.net.
FAU - Liu, Zhi
AU  - Liu Z
AUID- ORCID: 0000-0002-8464-3235
AD  - Department of Ultrasound, Nanfang Hospital, Southern Medical University, 
      Guangzhou, 510515, China. lzyysmile@163.com.
LA  - eng
GR  - 81701400/National Natural Science Foundation of China/
GR  - 2017A030310447/Natural Science Foundation of Guangdong Province/
GR  - 16020340650/Special Funding Program for Clinical Research from Chinese Medical 
      Association/
PT  - Journal Article
DEP - 20210122
PL  - England
TA  - Reprod Biol Endocrinol
JT  - Reproductive biology and endocrinology : RB&E
JID - 101153627
SB  - IM
MH  - Adult
MH  - China/epidemiology
MH  - Cohort Studies
MH  - Female
MH  - Humans
MH  - Hysteroscopy/methods
MH  - Infant, Newborn
MH  - Infertility, Female/diagnosis/epidemiology/surgery
MH  - Live Birth/epidemiology
MH  - Predictive Value of Tests
MH  - Pregnancy
MH  - *Pregnancy Rate
MH  - Retrospective Studies
MH  - Tissue Adhesions/diagnosis/epidemiology/*surgery
MH  - Treatment Outcome
MH  - Uterine Diseases/diagnosis/epidemiology/*surgery
PMC - PMC7821669
OTO - NOTNLM
OT  - Intrauterine adhesion
OT  - Live birth
OT  - Nasr classification
OT  - Transcervical resection of adhesion
COIS- All authors have declared no conflict of interest.
EDAT- 2021/01/24 06:00
MHDA- 2021/10/30 06:00
PMCR- 2021/01/22
CRDT- 2021/01/23 05:26
PHST- 2020/09/07 00:00 [received]
PHST- 2021/01/08 00:00 [accepted]
PHST- 2021/01/23 05:26 [entrez]
PHST- 2021/01/24 06:00 [pubmed]
PHST- 2021/10/30 06:00 [medline]
PHST- 2021/01/22 00:00 [pmc-release]
AID - 10.1186/s12958-021-00697-1 [pii]
AID - 697 [pii]
AID - 10.1186/s12958-021-00697-1 [doi]
PST - epublish
SO  - Reprod Biol Endocrinol. 2021 Jan 22;19(1):13. doi: 10.1186/s12958-021-00697-1.