PMID- 33486221
OWN - NLM
STAT- MEDLINE
DCOM- 20210216
LR  - 20210216
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1638
DP  - 2021 Feb 8
TI  - An electrodialytic device for automated inorganic anion preconcentration with 
      determination by ion chromatography-conductivity detection.
PG  - 461898
LID - S0021-9673(21)00022-4 [pii]
LID - 10.1016/j.chroma.2021.461898 [doi]
AB  - A 4-layer sandwiched device (4LSD) well suited for coupling to online ion 
      chromatography (IC) systems was described and simultaneously performed target 
      anion enrichment, matrix removal and sample injection within seconds. The basic 
      assembly consisted of an extraction solution channel, a sample solution channel 
      and two electrolyte channels. Cation-exchange resin (CER) was utilized to support 
      the solution chamber, increase electrical conductivity and improve pressure 
      resistance to achieve compatibility with a peristaltic pump. Filter placement 
      ensured loop circulation of the 4LSD and prevented resin leakage. The 4LSD showed 
      comparable performance to that of conventional solid-phase extraction (SPE) 
      pretreatment in terms of matrix interference removal while enabling automation. 
      The applied current, sample/extraction solution flow rate ratio, and initial 
      concentration were discussed and optimized. Controllable 1-40-fold enrichment can 
      be ensured. The migration phenomenon of different anions was discussed. F(-), 
      Cl(-), NO(2)(-), Br(-), NO(3)(-), SO(4)(2-) and ClO(4)(-) exhibited satisfactory 
      linear detection ranges within 2.5-1000 mug.L(-1), and the calculated limits of 
      detection (LODs) in milk formula were within the 0.097-0.79 mg.kg(-1) range. The 
      4LSD was successfully applied to the determination of anions in milk formula with 
      good spiked recoveries ranging between 92.54% and 107.2%, except for the NO(2)(-) 
      recovery. The relative standard deviations (RSDs) ranged from 0.69% to 8.29%.
CI  - Copyright (c) 2021. Published by Elsevier B.V.
FAU - Chen, Ning
AU  - Chen N
AD  - Department of Chemistry, Xixi Campus, Zhejiang University, Hangzhou 310027, 
      China.
FAU - Wu, Shuchao
AU  - Wu S
AD  - Zhejiang Inst Geol & Mineral Resources, Hangzhou 310007, China.
FAU - Zhu, Yan
AU  - Zhu Y
AD  - Department of Chemistry, Xixi Campus, Zhejiang University, Hangzhou 310027, 
      China; Key Laboratory of Health Risk Appraisal for Trace Toxic Chemicals of 
      Zhejiang Province, Zhejiang University, Hangzhou, Zhejiang, 310028, China. 
      Electronic address: zhuyan@zju.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20210113
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Anions)
RN  - 0 (Cation Exchange Resins)
SB  - IM
MH  - Animals
MH  - Anions/analysis
MH  - Automation
MH  - Cation Exchange Resins
MH  - Chromatography/*methods
MH  - *Electric Conductivity
MH  - Electrochemistry/*instrumentation/*methods
MH  - Limit of Detection
MH  - Milk/chemistry
MH  - Reproducibility of Results
MH  - Solid Phase Extraction
OTO - NOTNLM
OT  - 4-layer sandwiched device
OT  - Electrodialysis pre-enrichment
OT  - Ion chromatography
OT  - Resin filling
COIS- Declaration of Competing Interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2021/01/25 06:00
MHDA- 2021/02/17 06:00
CRDT- 2021/01/24 20:38
PHST- 2020/11/04 00:00 [received]
PHST- 2021/01/06 00:00 [revised]
PHST- 2021/01/07 00:00 [accepted]
PHST- 2021/01/25 06:00 [pubmed]
PHST- 2021/02/17 06:00 [medline]
PHST- 2021/01/24 20:38 [entrez]
AID - S0021-9673(21)00022-4 [pii]
AID - 10.1016/j.chroma.2021.461898 [doi]
PST - ppublish
SO  - J Chromatogr A. 2021 Feb 8;1638:461898. doi: 10.1016/j.chroma.2021.461898. Epub 
      2021 Jan 13.