PMID- 33486878 OWN - NLM STAT- MEDLINE DCOM- 20211215 LR - 20211215 IS - 1753-0407 (Electronic) IS - 1753-0407 (Linking) VI - 13 IP - 8 DP - 2021 Aug TI - Measuring the global, regional, and national burden of type 2 diabetes and the attributable risk factors in all 194 countries. PG - 613-639 LID - 10.1111/1753-0407.13159 [doi] AB - BACKGROUND: No detailed quantitative global, regional, or national estimates of the disability-adjusted life years (DALYs) of type 2 diabetes mellitus (T2DM) are available. METHODS: We used data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 to estimate the global, regional, and national incidence rates and DALYs of T2DM, as well as the associated risk factors, in all 194 countries and territories by age, sex, and sociodemographic status during the period from 2007 to 2017. RESULTS: Globally, the age-standardized incidence and DALY rates increased by 3.23% and 5.07% during 2007 to 2017, respectively. The age-standardized incidence and DALY rates in 2017 and the corresponding percentage changes during 2007 to 2017 were highest in the low-middle sociodemographic index (SDI) quintile. Regionally, the highest 2017 age-standardized incidence and DALY rates were observed in Oceania, whereas the largest percentage increases in both rates during 2007 to 2017 were observed in Southeast Asia. Nationally, Iran, the United Kingdom, and Indonesia reported the largest percentage increases in the age-standardized incidence rates, whereas Georgia, Czech Republic, and Iran showed the largest percentage increases in the age-standardized DALY rates. Globally, the largest percentage increases in risk-attributable DALYs were associated with a high body mass index, low physical activity level, high fasting plasma glucose level, and high sugar-sweetened beverage and red meat consumption. CONCLUSIONS: The global T2DM age-standardized incidence and DALY rates increased globally between 2007 and 2017, especially in the low-middle SDI quintile, Southeast Asia. CI - (c) 2021 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and John Wiley & Sons Australia, Ltd. FAU - Yu, Mei AU - Yu M AD - Department of Endocrinology, People's Hospital of Yuyao, Ningbo, China. FAU - Zhan, Xiaoqing AU - Zhan X AUID- ORCID: 0000-0002-7476-8931 AD - Department of Geriatrics and Traditional Chinese Medicine, People's Hospital of Yuyao, Ningbo, China. FAU - Yang, Zhenxing AU - Yang Z AD - Department of Endocrinology, People's Hospital of Yuyao, Ningbo, China. FAU - Huang, Yongmin AU - Huang Y AD - Department of Endocrinology, People's Hospital of Yuyao, Ningbo, China. LA - eng GR - 2017YFC1310902/National Key R&D Program of China/ GR - 2018YFC1315305/National Key R&D Program of China/ GR - PPXK2018-02/Ningbo Health Branding Subject Fund/ GR - SZSM201803080/Sanming Project of Medicine in Shen-zhen/ PT - Journal Article DEP - 20210212 PL - Australia TA - J Diabetes JT - Journal of diabetes JID - 101504326 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Cost of Illness MH - Diabetes Mellitus, Type 2/*epidemiology/etiology MH - Disability-Adjusted Life Years MH - Female MH - Global Health MH - Humans MH - Incidence MH - Male MH - Middle Aged MH - Risk Factors MH - Young Adult OTO - NOTNLM OT - 2型糖尿病 OT - disability-adjusted life years OT - global burden of disease OT - incidence OT - type 2 diabetes mellitus OT - 全球疾病负担 OT - 发病率 OT - 残疾调整生命年 EDAT- 2021/01/25 06:00 MHDA- 2021/12/16 06:00 CRDT- 2021/01/24 20:55 PHST- 2021/01/11 00:00 [revised] PHST- 2020/11/16 00:00 [received] PHST- 2021/01/20 00:00 [accepted] PHST- 2021/01/25 06:00 [pubmed] PHST- 2021/12/16 06:00 [medline] PHST- 2021/01/24 20:55 [entrez] AID - 10.1111/1753-0407.13159 [doi] PST - ppublish SO - J Diabetes. 2021 Aug;13(8):613-639. doi: 10.1111/1753-0407.13159. Epub 2021 Feb 12.