PMID- 33487076
OWN - NLM
STAT- MEDLINE
DCOM- 20221123
LR  - 20221123
IS  - 1476-4954 (Electronic)
IS  - 1476-4954 (Linking)
VI  - 35
IP  - 25
DP  - 2022 Dec
TI  - Developmental outcomes in children from cryopreserved embryos compared to their 
      siblings from fresh embryo transfers: a case series.
PG  - 4952-4955
LID - 10.1080/14767058.2021.1873938 [doi]
AB  - OBJECTIVE: This study aimed to evaluate the developmental outcomes in children 
      from cryopreserved embryos, with minimum influences of interparental variation 
      that would cause potential bias. Hence we examined siblings, in which the older 
      sibs were from fresh embryo transfers, while the younger sibs were from 
      cryopreserved embryos. METHODS: Three pairs of siblings were evaluated. All 
      routine prenatal and neonatal evaluation were performed, while personal-social, 
      language, fine and gross motor evaluation were all evaluated by the Denver 
      Developmental Screening Test (DDST)-II. Wechsler Preschool and Primary Scale of 
      Intelligence (WPPSI) test was used to measure the Intelligent Quotient (IQ) in 5 
      of 6 children. RESULTS: Standard prenatal measurements of all children suggested 
      uneventful pregnancies, followed by uneventful deliveries. DDST-II results showed 
      that the aspects of personal-social, language, fine and gross motor in every 
      child are as expected according to their ages. Results from WPPSI tests suggest 
      that 5 of 6 evaluated children acquired average to high-average intelligences. 
      CONCLUSIONS: The results suggest that the developmental outcomes in children from 
      cryopreserved embryos have no significant differences with the outcomes in 
      children from fresh embryo transfers.
FAU - Djuwantono, Tono
AU  - Djuwantono T
AUID- ORCID: 0000-0002-5165-6371
AD  - Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas 
      Padjadjaran-Dr. Hasan Sadikin Hospital, Bandung, Indonesia.
FAU - Permadi, Wiryawan
AU  - Permadi W
AD  - Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas 
      Padjadjaran-Dr. Hasan Sadikin Hospital, Bandung, Indonesia.
FAU - Ekapatria, Christofani
AU  - Ekapatria C
AD  - Department of Obstetrics and Gynecology, Universitas Pelita Harapan Medical 
      School-Siloam Hospital, Karawaci, Tangerang, Banten, Indonesia.
FAU - Halim, Danny
AU  - Halim D
AD  - Department of Neurosurgery, Faculty of Medicine, Universitas Padjadjaran-Dr. 
      Hasan Sadikin Hospital, Bandung, Indonesia.
FAU - Faried, Ahmad
AU  - Faried A
AD  - Department of Neurosurgery, Faculty of Medicine, Universitas Padjadjaran-Dr. 
      Hasan Sadikin Hospital, Bandung, Indonesia.
LA  - eng
PT  - Journal Article
DEP - 20210124
PL  - England
TA  - J Matern Fetal Neonatal Med
JT  - The journal of maternal-fetal & neonatal medicine : the official journal of the 
      European Association of Perinatal Medicine, the Federation of Asia and Oceania 
      Perinatal Societies, the International Society of Perinatal Obstetricians
JID - 101136916
SB  - IM
MH  - Child, Preschool
MH  - Child
MH  - Infant, Newborn
MH  - Pregnancy
MH  - Female
MH  - Humans
MH  - *Siblings
MH  - *Embryo Transfer
MH  - Wechsler Scales
MH  - Intelligence Tests
MH  - Cryopreservation
OTO - NOTNLM
OT  - Cryopreserved embryos
OT  - Denver Developmental Screening Test (DDST)
OT  - Intelligent Quotient (IQ)
OT  - fresh embryo transfers
EDAT- 2021/01/26 06:00
MHDA- 2022/11/24 06:00
CRDT- 2021/01/25 05:25
PHST- 2021/01/26 06:00 [pubmed]
PHST- 2022/11/24 06:00 [medline]
PHST- 2021/01/25 05:25 [entrez]
AID - 10.1080/14767058.2021.1873938 [doi]
PST - ppublish
SO  - J Matern Fetal Neonatal Med. 2022 Dec;35(25):4952-4955. doi: 
      10.1080/14767058.2021.1873938. Epub 2021 Jan 24.