PMID- 33488813
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231110
IS  - 1831-4732 (Electronic)
IS  - 1831-4732 (Linking)
VI  - 19
IP  - 1
DP  - 2021 Jan
TI  - Reasoned opinion on the toxicological properties and maximum residue levels for 
      propoxur.
PG  - e06374
LID - 10.2903/j.efsa.2021.6374 [doi]
LID - e06374
AB  - In accordance with Article 43 of Regulation (EC) No 396/2005, the European 
      Commission requested EFSA to prepare a reasoned opinion on the toxicological 
      properties and the existing maximum residue levels (MRLs) set for propoxur. EFSA 
      was requested to assess the toxicological properties of propoxur and derive 
      toxicological reference values, based on the toxicological assessment performed 
      by Health Canada. EFSA was also requested to review the information provided by 
      Member States and the UK on the metabolism of propoxur in plants and animals and 
      on the current MRLs, as well as the limit of quantification (LOQ) that can be 
      achieved with analytical methods used in MRL enforcement. Based on the 
      information available to EFSA, toxicological reference values could not be 
      derived for propoxur. No evidence was provided by Member States and UK that the 
      existing EU MRLs need to be maintained as import tolerances. Information to 
      support the current MRLs or alternative MRLs have not been provided by Member 
      States and the UK. Codex MRLs are not in place. EFSA therefore recommended 
      lowering of all existing EU MRLs for propoxur to the LOQ. According to the EU 
      Reference Laboratories, sufficiently validated analytical methods are available 
      to analyse for propoxur residues in all plant and animal commodities. Lacking 
      toxicological reference values derived at EU level, a conclusion cannot be 
      derived whether the setting of MRLs at the LOQs is sufficiently protective for 
      the European consumers.
CI  - (c) 2021 European Food Safety Authority. EFSA Journal published by John Wiley and 
      Sons Ltd on behalf of European Food Safety Authority.
CN  - European Food Safety Authority (EFSA)
FAU - Anastassiadou, Maria
AU  - Anastassiadou M
FAU - Bernasconi, Giovanni
AU  - Bernasconi G
FAU - Brancato, Alba
AU  - Brancato A
FAU - Carrasco Cabrera, Luis
AU  - Carrasco Cabrera L
FAU - Ferreira, Lucien
AU  - Ferreira L
FAU - Greco, Luna
AU  - Greco L
FAU - Jarrah, Samira
AU  - Jarrah S
FAU - Kazocina, Aija
AU  - Kazocina A
FAU - Leuschner, Renata
AU  - Leuschner R
FAU - Magrans, Jose Oriol
AU  - Magrans JO
FAU - Miron, Ileana
AU  - Miron I
FAU - Nave, Stefanie
AU  - Nave S
FAU - Pedersen, Ragnor
AU  - Pedersen R
FAU - Reich, Hermine
AU  - Reich H
FAU - Rojas, Alejandro
AU  - Rojas A
FAU - Sacchi, Angela
AU  - Sacchi A
FAU - Santos, Miguel
AU  - Santos M
FAU - Scarlato, Alessia Pia
AU  - Scarlato AP
FAU - Theobald, Anne
AU  - Theobald A
FAU - Vagenende, Benedicte
AU  - Vagenende B
FAU - Verani, Alessia
AU  - Verani A
LA  - eng
PT  - Journal Article
DEP - 20210118
PL  - United States
TA  - EFSA J
JT  - EFSA journal. European Food Safety Authority
JID - 101642076
PMC - PMC7812492
OTO - NOTNLM
OT  - MRL
OT  - Propoxur
OT  - Regulation (EC) No 396/2005
OT  - consumer risk assessment
OT  - pesticide
EDAT- 2021/01/26 06:00
MHDA- 2021/01/26 06:01
PMCR- 2021/01/18
CRDT- 2021/01/25 05:40
PHST- 2021/01/25 05:40 [entrez]
PHST- 2021/01/26 06:00 [pubmed]
PHST- 2021/01/26 06:01 [medline]
PHST- 2021/01/18 00:00 [pmc-release]
AID - EFS26374 [pii]
AID - 10.2903/j.efsa.2021.6374 [doi]
PST - epublish
SO  - EFSA J. 2021 Jan 18;19(1):e06374. doi: 10.2903/j.efsa.2021.6374. eCollection 2021 
      Jan.