PMID- 33489105 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220420 IS - 2049-0801 (Print) IS - 2049-0801 (Electronic) IS - 2049-0801 (Linking) VI - 61 DP - 2021 Jan TI - Comparative study between intersphinecteric ligation of perianal fistula versus conventional fistulotomy with or without seton in the treatment of perianal fistula: A prospective randomized controlled trial. PG - 180-184 LID - 10.1016/j.amsu.2020.12.014 [doi] AB - BACKGROUND: Fistula-in-ano is one of the most common benign anal conditions in daily surgical practice.The goals in the treatment of an anal fistula are to eradicate sepsis and to eliminate the primary fistula opening, any associated tracts, and any secondary openings without a change in continence. Conventional fistulotomy (lay open of the fistula tract) is a commonly used procedure and is still relied on by the majority of surgeons as the gold standard for the treatment of perianal fistula. Ligation of the Intersphincteric Fistula Tract (LIFT) is a new sphincter-preserving technique for the treatment of anal fistula. OBJECTIVE: To compare the efficacy of open fistulotomy and ligation of intersphincteric fistula tract (LIFT) procedure based on its post-operative outcomes. PATIENTS AND METHODS: The Present study is A prospective randomized controlled trial which included 30 patients presented with low transsphincteric perianal fistula 27 (90%) males and 3 (10%) females divided into two groups each group consisted of 15 patients. Group, I subjected to inter sphincteric ligation of perianal fistula (LIFT) procedure. Group II patients subjected to conventional fistulotomy. The study lasts 2 years from May 2017 to May 2019 with Follow up for 6 months duration. Operative time in our study was significantly higher in group (I) Managed by LIFT with a mean of 32.53 min than group (II) managed by fistulotomy with a mean of 20.87mins. Wound healing was faster in a group (I) managed by LIFT than group (II) managed by fistulotomy, as the mean time for complete wound healing was (4.53) weeks after LIFT and (5.67) weeks after fistulotomy. RESULTS: There was no case of incontinence after performing the LIFT technique in all our patients in group I. there were 2 cases of incontinence to gases only after fistulotomy in group II. The healing rate after LIFT was 80% (12/15 patients). The healing rate after fistulotomy was 93.3% (14/15 patients). CONCLUSION: LIFT procedure is an effective and preferred sphincter-saving technique for fistula-in-ano with shorter healing time and lower incidence of postoperative anal incontinence, as compared to open fistulotomy. CI - (c) 2020 The Authors. FAU - Al Sebai, Olfat I AU - Al Sebai OI AD - General and Colorectal Surgery, Faculty of Medicine, Menoufia University, Egypt. FAU - Ammar, Mohammed S AU - Ammar MS AD - General Surgery, Faculty of Medicine, Menoufia University, Egypt. FAU - Mohamed, Samy H AU - Mohamed SH AD - General Surgery Resident, Ministry of Health, Egypt. FAU - El Balshy, Mohammed A AU - El Balshy MA AD - General Surgery, Faculty of Medicine, Menoufia University, Egypt. LA - eng PT - Journal Article DEP - 20201218 PL - England TA - Ann Med Surg (Lond) JT - Annals of medicine and surgery (2012) JID - 101616869 PMC - PMC7804334 OTO - NOTNLM OT - Conventional fistulotomy OT - Fistula-in-ano as common benign anal conditions in daily surgical practice OT - Ligation of intersphincteric fistula tract OT - New trends in the treatment of perianal fistula OT - Sphincter saving techniques for fistula in ano EDAT- 2021/01/26 06:00 MHDA- 2021/01/26 06:01 PMCR- 2020/12/18 CRDT- 2021/01/25 05:41 PHST- 2020/11/15 00:00 [received] PHST- 2020/12/09 00:00 [revised] PHST- 2020/12/10 00:00 [accepted] PHST- 2021/01/25 05:41 [entrez] PHST- 2021/01/26 06:00 [pubmed] PHST- 2021/01/26 06:01 [medline] PHST- 2020/12/18 00:00 [pmc-release] AID - S2049-0801(20)30532-X [pii] AID - 10.1016/j.amsu.2020.12.014 [doi] PST - epublish SO - Ann Med Surg (Lond). 2020 Dec 18;61:180-184. doi: 10.1016/j.amsu.2020.12.014. eCollection 2021 Jan.