PMID- 33489491
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210126
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 12
IP  - 12
DP  - 2020 Dec 14
TI  - Multiple Endocrine Neoplasia Type 1 Syndrome: A Case Report and Review of 
      Literature.
PG  - e12073
LID - 10.7759/cureus.12073 [doi]
LID - e12073
AB  - Multiple endocrine neoplasia type 1 (MEN1) or Wermer's syndrome is a genetic 
      disease characterized by involvement of multiple endocrine glands, primarily 
      involving parathyroid, pancreas, and pituitary. Other additional features include 
      foregut carcinoids; non-functioning adrenal tumors; and skin lesions such as 
      lipomas, collagenomas, and angiofibromas. Here, we describe our experience in 
      managing a patient who presented to us with spontaneous episodes of hypoglycemia 
      and was diagnosed with insulinoma. Detailed clinical and biochemical evaluation 
      unraveled the diagnosis of MEN1 in the patient and her family members who 
      constituted a large kindred. This case highlights the importance for evaluation 
      of MEN1 in a patient or his/her family members in the setting of clinical and 
      biochemical suspicion. In addition, we have also discussed the utility of the 
      latest diagnostic and therapeutic modalities for management of MEN1.
CI  - Copyright (c) 2020, Boro et al.
FAU - Boro, Hiya
AU  - Boro H
AD  - Endocrinology, Diabetes, and Metabolism, All India Institute of Medical Sciences, 
      New Delhi, IND.
FAU - Kubihal, Suraj
AU  - Kubihal S
AD  - Endocrinology, Diabetes, and Metabolism, All India Institute of Medical Sciences, 
      New Delhi, IND.
FAU - Arora, Saurabh
AU  - Arora S
AD  - Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, IND.
FAU - Kubihal, Vijay
AU  - Kubihal V
AD  - Radiology, All India Institute of Medical Sciences, New Delhi, IND.
FAU - Tandon, Nikhil
AU  - Tandon N
AD  - Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, 
      IND.
LA  - eng
PT  - Case Reports
DEP - 20201214
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC7805507
OTO - NOTNLM
OT  - insulinoma
OT  - pancreatic net
OT  - parathyroid adenoma
OT  - pituitary adenoma
COIS- The authors have declared that no competing interests exist.
EDAT- 2021/01/26 06:00
MHDA- 2021/01/26 06:01
PMCR- 2020/12/14
CRDT- 2021/01/25 05:42
PHST- 2021/01/25 05:42 [entrez]
PHST- 2021/01/26 06:00 [pubmed]
PHST- 2021/01/26 06:01 [medline]
PHST- 2020/12/14 00:00 [pmc-release]
AID - 10.7759/cureus.12073 [doi]
PST - epublish
SO  - Cureus. 2020 Dec 14;12(12):e12073. doi: 10.7759/cureus.12073.