PMID- 33493851
OWN - NLM
STAT- MEDLINE
DCOM- 20211102
LR  - 20211102
IS  - 1878-0334 (Electronic)
IS  - 1871-4021 (Linking)
VI  - 15
IP  - 1
DP  - 2021 Jan-Feb
TI  - Decreased handgrip strength in patients with type 2 diabetes: A cross-sectional 
      study in a tertiary care hospital in north India.
PG  - 325-329
LID - S1871-4021(21)00009-6 [pii]
LID - 10.1016/j.dsx.2021.01.007 [doi]
AB  - BACKGROUND AND AIMS: Type 2 diabetes mellitus (T2DM) has been associated with low 
      muscle mass and strength. India has second highest number of diabetes cases 
      worldwide. Till date, muscle mass and strength of Asian Indians with T2DM are not 
      well studied. Aim of the study was to compare the skeletal muscle mass and muscle 
      strength between individuals with and without T2DM. METHODS: This cross-sectional 
      study, included subjects with T2DM, age 18-70 years and age and sex-matched 
      individuals without diabetes (controls). Body composition was assessed using 
      Inbody 570 body composition analyser. Hand grip strength (HGS) was measured using 
      JAMAR's Hydraulic Hand Dynamometer. RESULTS: Total of 194 subjects (95 T2DM and 
      99 controls) were studied. Mean HGS (kg) was significantly lower both in men and 
      women with diabetes compared with controls (32.4 +/- 7.9 vs 37.9 +/- 8.1, p = 0.001 
      in men and 20.6 +/- 6.4 vs 23.1 +/- 4.06, p = 0.02 in women). Significantly higher 
      percentage of men and women with diabetes had sarcopenia compared with controls 
      (44.4% vs 15.1% in men and 51% vs 20% in women). In multivariate logistic 
      regression analysis, diabetes was an independent risk factor for low HGS in both 
      men (OR = 6.6) and women (OR = 3.4) after adjusting for age, smoking, alcohol 
      consumption, obesity, physical activity and dietary protein intake. CONCLUSION: 
      HGS was significantly lower in subjects with T2DM compared with subjects without 
      diabetes. Diabetes was an independent risk factor for low HGS.
CI  - Copyright (c) 2021 Diabetes India. Published by Elsevier Ltd. All rights reserved.
FAU - Kaur, Parjeet
AU  - Kaur P
AD  - Department of Endocrinology and Diabetes, Medanta the Medicity, Gurugram, 
      Haryana, 122001, India. Electronic address: parjeets@yahoo.com.
FAU - Bansal, Ritesh
AU  - Bansal R
AD  - Department of Endocrinology and Diabetes, Medanta the Medicity, Gurugram, 
      Haryana, 122001, India.
FAU - Bhargava, Bharti
AU  - Bhargava B
AD  - Department of Endocrinology and Diabetes, Medanta the Medicity, Gurugram, 
      Haryana, 122001, India.
FAU - Mishra, Sunil
AU  - Mishra S
AD  - Department of Endocrinology and Diabetes, Medanta the Medicity, Gurugram, 
      Haryana, 122001, India.
FAU - Gill, Harmandeep
AU  - Gill H
AD  - Department of Endocrinology and Diabetes, Medanta the Medicity, Gurugram, 
      Haryana, 122001, India.
FAU - Mithal, Ambrish
AU  - Mithal A
AD  - Department of Endocrinology and Diabetes, Medanta the Medicity, Gurugram, 
      Haryana, 122001, India.
LA  - eng
PT  - Journal Article
DEP - 20210114
PL  - Netherlands
TA  - Diabetes Metab Syndr
JT  - Diabetes & metabolic syndrome
JID - 101462250
SB  - IM
MH  - Adult
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus, Type 2/diagnosis/*epidemiology/*physiopathology
MH  - Female
MH  - Hand Strength/*physiology
MH  - Humans
MH  - India/epidemiology
MH  - Male
MH  - Middle Aged
MH  - Muscle Strength/physiology
MH  - *Tertiary Care Centers
OTO - NOTNLM
OT  - Hand grip strength
OT  - Sarcopenia
OT  - Skeletal muscle mass
OT  - Type 2 diabetes
COIS- Declaration of competing interest No financial interests and relationships and 
      affiliations relevant to the subject of the manuscript.
EDAT- 2021/01/26 06:00
MHDA- 2021/11/03 06:00
CRDT- 2021/01/25 20:14
PHST- 2020/10/10 00:00 [received]
PHST- 2020/12/25 00:00 [revised]
PHST- 2021/01/07 00:00 [accepted]
PHST- 2021/01/26 06:00 [pubmed]
PHST- 2021/11/03 06:00 [medline]
PHST- 2021/01/25 20:14 [entrez]
AID - S1871-4021(21)00009-6 [pii]
AID - 10.1016/j.dsx.2021.01.007 [doi]
PST - ppublish
SO  - Diabetes Metab Syndr. 2021 Jan-Feb;15(1):325-329. doi: 10.1016/j.dsx.2021.01.007. 
      Epub 2021 Jan 14.