PMID- 33496931
OWN - NLM
STAT- MEDLINE
DCOM- 20210419
LR  - 20210419
IS  - 1708-0428 (Electronic)
IS  - 0960-8923 (Linking)
VI  - 31
IP  - 5
DP  - 2021 May
TI  - Applying an Anti-reflux Suture in the One Anastomosis Gastric Bypass to Prevent 
      Biliary Reflux: a Long-Term Observational Study.
PG  - 2144-2152
LID - 10.1007/s11695-021-05238-8 [doi]
AB  - INTRODUCTION: The one anastomosis gastric bypass (OAGB) is an effective treatment 
      to induce sustained weight loss in morbidly obese patients. Concerns remain 
      regarding the development of reflux. The aim of this study was to investigate the 
      effect of an "anti-reflux suture" as anti-reflux modification to prevent reflux. 
      METHOD: This is a single-center retrospective cohort study of patients who 
      underwent a primary OAGB at the Center Obesity North-Netherlands (CON) between 
      January 2015 and December 2016. Reflux was defined as symptoms of acid/bilious 
      regurgitation or pyrosis. This was consequently asked and reported at each 
      follow-up visit. Outcomes of patients with an anti-reflux suture were compared to 
      those without. RESULTS: In 414 (59%) of the 703 included patients, an anti-reflux 
      suture was applied. Follow-up at 3 years was 74%. The incidence of reflux did not 
      differ between patients with or without an anti-reflux suture (57 versus 56%, 
      respectively; P = 0.9). The presence of an anti-reflux suture was significantly 
      associated with a lower incidence of conversion to Roux-en-Y gastric bypass 
      (RYGB) for reflux (OR 0.56, 95%CI 0.34-0.91). Patients preoperatively diagnosed 
      with gastroesophageal reflux disease (GERD) were 5.2 times more likely to need a 
      conversion to RYGB for reflux (95%CI 2.7-10.1). CONCLUSION: The presence of 
      preoperative GERD should be weighted heavily in the decision to perform an OAGB 
      as this is a major risk factor for conversion surgery due to reflux. The 
      anti-reflux suture might be a valuable addition to the procedure of the OAGB 
      because it results in fewer conversion surgeries for reflux.
FAU - Slagter, Nienke
AU  - Slagter N
AUID- ORCID: 0000-0001-6729-7791
AD  - Center for Obesity Northern-Netherlands (CON), Medical Center Leeuwarden, 
      Leeuwarden, the Netherlands. Nienke.Slagter@mcl.nl.
FAU - Hopman, Jonne
AU  - Hopman J
AD  - Center for Obesity Northern-Netherlands (CON), Medical Center Leeuwarden, 
      Leeuwarden, the Netherlands.
FAU - Altenburg, Anna G
AU  - Altenburg AG
AD  - Center for Obesity Northern-Netherlands (CON), Medical Center Leeuwarden, 
      Leeuwarden, the Netherlands.
FAU - de Heide, Loek J M
AU  - de Heide LJM
AD  - Center for Obesity Northern-Netherlands (CON), Medical Center Leeuwarden, 
      Leeuwarden, the Netherlands.
FAU - Jutte, Ewoud H
AU  - Jutte EH
AD  - Center for Obesity Northern-Netherlands (CON), Medical Center Leeuwarden, 
      Leeuwarden, the Netherlands.
FAU - Kaijser, Mirjam A
AU  - Kaijser MA
AD  - Center for Obesity Northern-Netherlands (CON), Medical Center Leeuwarden, 
      Leeuwarden, the Netherlands.
FAU - Damen, Stefan L
AU  - Damen SL
AD  - Center for Obesity Northern-Netherlands (CON), Medical Center Leeuwarden, 
      Leeuwarden, the Netherlands.
FAU - van Beek, Andre P
AU  - van Beek AP
AD  - Department of Endocrinology, University of Groningen, University Medical Center 
      Groningen, Groningen, the Netherlands.
FAU - Emous, Marloes
AU  - Emous M
AD  - Center for Obesity Northern-Netherlands (CON), Medical Center Leeuwarden, 
      Leeuwarden, the Netherlands.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20210126
PL  - United States
TA  - Obes Surg
JT  - Obesity surgery
JID - 9106714
SB  - IM
MH  - *Gastric Bypass
MH  - *Gastroesophageal Reflux/epidemiology/etiology/prevention & control
MH  - Humans
MH  - Netherlands
MH  - *Obesity, Morbid/surgery
MH  - Retrospective Studies
MH  - Sutures
OTO - NOTNLM
OT  - Bariatric surgery
OT  - Biliary reflux
OT  - Gastroesophageal reflux disease
OT  - Mini gastric bypass
OT  - One anastomosis gastric bypass
EDAT- 2021/01/27 06:00
MHDA- 2021/04/20 06:00
CRDT- 2021/01/26 12:12
PHST- 2020/11/12 00:00 [received]
PHST- 2021/01/14 00:00 [accepted]
PHST- 2021/01/14 00:00 [revised]
PHST- 2021/01/27 06:00 [pubmed]
PHST- 2021/04/20 06:00 [medline]
PHST- 2021/01/26 12:12 [entrez]
AID - 10.1007/s11695-021-05238-8 [pii]
AID - 10.1007/s11695-021-05238-8 [doi]
PST - ppublish
SO  - Obes Surg. 2021 May;31(5):2144-2152. doi: 10.1007/s11695-021-05238-8. Epub 2021 
      Jan 26.