PMID- 3349995
OWN - NLM
STAT- MEDLINE
DCOM- 19880502
LR  - 20190828
IS  - 0301-5548 (Print)
IS  - 0301-5548 (Linking)
VI  - 57
IP  - 2
DP  - 1988
TI  - The effects of a glycogen loading regimen on acid-base status and blood lactate 
      concentration before and after a fixed period of high intensity exercise in man.
PG  - 254-9
AB  - Six healthy male subjects exercised after an overnight fast for a fixed 3 min 
      period at a workload equivalent to 100% of their maximal oxygen uptake (VO2max) 
      on 3 separate occasions. The first test took place after subjects had consumed a 
      mixed diet (43 +/- 3% carbohydrate (CHO), 41 +/- 5% fat and 16 +/- 3% protein) 
      for 3 days, and was followed 2 h later by prolonged cycling to exhaustion at 77 
      +/- 3% VO2max to deplete muscle glycogen stores. Following this, subjects 
      consumed a low CHO diet (4 +/- 1% CHO, 63 +/- 5% fat and 33 +/- 6% protein) for 
      the remainder of the day and for the subsequent 2 days; on the morning of the 
      next day a second high intensity test took place. Finally subjects followed a 3 
      day high CHO diet (73 +/- 7% CHO, 17 +/- 6% fat and 10 +/- 1% protein) before 
      their last test. Acid-base status and selected metabolites were measured on 
      arterialized-venous blood at rest prior to exercise and at intervals for 15 min 
      following exercise. Prior to exercise, plasma pH and blood lactate concentration 
      were higher (p less than 0.05) after the high CHO diet when compared with the low 
      CHO diet. Pre-exercise plasma bicarbonate, blood PCO2 and blood base excess were 
      all higher after the high (p less than 0.001, p less than 0.01, p less than 0.01 
      respectively) and normal (p less than 0.05, p less than 0.05, p less than 0.05 
      respectively) CHO diets when compared with the low CHO diet.(ABSTRACT TRUNCATED 
      AT 250 WORDS)
FAU - Greenhaff, P L
AU  - Greenhaff PL
AD  - Department of Environmental and Occupational Medicine, University Medical School, 
      Aberdeen, Scotland, UK.
FAU - Gleeson, M
AU  - Gleeson M
FAU - Maughan, R J
AU  - Maughan RJ
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Germany
TA  - Eur J Appl Physiol Occup Physiol
JT  - European journal of applied physiology and occupational physiology
JID - 0410266
RN  - 0 (Bicarbonates)
RN  - 0 (Blood Glucose)
RN  - 0 (Lactates)
RN  - 9005-79-2 (Glycogen)
SB  - IM
MH  - *Acid-Base Equilibrium
MH  - Adult
MH  - Bicarbonates/blood
MH  - Blood Glucose/analysis
MH  - Diet
MH  - Glycogen/*administration & dosage
MH  - Humans
MH  - Lactates/*blood
MH  - Male
MH  - *Physical Exertion
MH  - Time Factors
EDAT- 1988/01/01 00:00
MHDA- 1988/01/01 00:01
CRDT- 1988/01/01 00:00
PHST- 1988/01/01 00:00 [pubmed]
PHST- 1988/01/01 00:01 [medline]
PHST- 1988/01/01 00:00 [entrez]
AID - 10.1007/BF00640672 [doi]
PST - ppublish
SO  - Eur J Appl Physiol Occup Physiol. 1988;57(2):254-9. doi: 10.1007/BF00640672.