PMID- 33509417 OWN - NLM STAT- MEDLINE DCOM- 20210728 LR - 20210728 IS - 1873-6483 (Electronic) IS - 0740-5472 (Linking) VI - 122 DP - 2021 Mar TI - Treatment admissions for opioids, cocaine, and methamphetamines among adolescents and emerging adults after legalization of recreational marijuana. PG - 108228 LID - S0740-5472(20)30485-2 [pii] LID - 10.1016/j.jsat.2020.108228 [doi] AB - BACKGROUND: A public health concern stemming from recreational marijuana legalization (RML) is the idea that marijuana may act as a "gateway" drug among youth and young adults, where growing marijuana use will lead to increasing substance use disorder (SUD) for "harder" illicit drugs. This study investigates whether SUD treatment admissions for cocaine, opioids, and methamphetamines increased following RML enactment in Colorado and Washington for adolescents and emerging adults. METHODS: We entered annual 2008-2017 treatment admissions data from the SAMHSA Treatment Episode Dataset - Admissions (TEDS-A) into difference-in-differences models to investigate whether the difference in treatment admissions for cocaine, opioids, and methamphetamines among adolescents (12-17), early emerging adults (18-20), and late emerging adults (21-24) before versus after RML enactment differed between Colorado and Washington and states without RML. RESULTS: There was no significant difference (p < 0.05) between Colorado and Washington and other states in the pre- versus postlegalization trajectories of SUD treatment admissions for cocaine, opioids, or methamphetamines for adolescents (beta = -0.152, 95% CI = -0.500, 0.196; beta = -0.374, 95% CI = -1.188, 0.439; beta = 0.787, 95% CI = -0.511, 2.084, respectively), early emerging adults (beta = -0.153, 95% CI = -0.762, 0.455; beta = 0.960, 95% CI = -4.771, 6.692; beta = 0.406, 95% CI = -2.232, 3.044, respectively) or late emerging adults (beta = -0.347, 95% CI = -1.506, 0.812; beta = -4.417, 95% CI = -16.264, 7.431; beta = 1.804, 95% CI = -2.315, 5.923, respectively). CONCLUSION: RML in Washington and Colorado was not associated with an increase in adolescent or emerging adult SUD treatment admissions for opioids, cocaine, or methamphetamines. Future studies should extend this research to other states, other substances, for older adults, and over longer time periods; and consider how the effects of drug policies may differ across different jurisdictions. CI - Copyright (c) 2020 Elsevier Inc. All rights reserved. FAU - Mennis, Jeremy AU - Mennis J AD - Department of Geography and Urban Studies, Temple University, 1115 Polett Walk, 308 Gladfelter Hall, Philadelphia, PA 19122, United States of America. Electronic address: jmennis@temple.edu. FAU - Stahler, Gerald J AU - Stahler GJ AD - Department of Geography and Urban Studies, Temple University, 1115 Polett Walk, 308 Gladfelter Hall, Philadelphia, PA 19122, United States of America. Electronic address: jstahler@temple.edu. FAU - Mason, Michael J AU - Mason MJ AD - Center for Behavioral Health Research, University of Tennessee, 1618 W. Cumberland Ave, 201 Henson Hall, Knoxville, TN 37996-3332, United States of America. Electronic address: mmason29@utk.edu. LA - eng PT - Journal Article DEP - 20201203 PL - United States TA - J Subst Abuse Treat JT - Journal of substance abuse treatment JID - 8500909 RN - 0 (Analgesics, Opioid) RN - 44RAL3456C (Methamphetamine) RN - I5Y540LHVR (Cocaine) SB - IM MH - Adolescent MH - Aged MH - Analgesics, Opioid MH - *Cannabis MH - *Cocaine/adverse effects MH - Colorado/epidemiology MH - Humans MH - *Marijuana Smoking MH - *Methamphetamine MH - Washington/epidemiology MH - Young Adult OTO - NOTNLM OT - Cannabis OT - Gateway drug OT - Legalization OT - Marijuana OT - Substance use disorder OT - Treatment EDAT- 2021/01/30 06:00 MHDA- 2021/07/29 06:00 CRDT- 2021/01/29 05:41 PHST- 2020/03/16 00:00 [received] PHST- 2020/10/21 00:00 [revised] PHST- 2020/11/26 00:00 [accepted] PHST- 2021/01/29 05:41 [entrez] PHST- 2021/01/30 06:00 [pubmed] PHST- 2021/07/29 06:00 [medline] AID - S0740-5472(20)30485-2 [pii] AID - 10.1016/j.jsat.2020.108228 [doi] PST - ppublish SO - J Subst Abuse Treat. 2021 Mar;122:108228. doi: 10.1016/j.jsat.2020.108228. Epub 2020 Dec 3.